Patents by Inventor Richard Bicker

Richard Bicker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6989462
    Abstract: A process is described for preparing compounds of formula (I) where R is H, optionally halogen-substituted alkyl, cycloalkyl, aryl, alkyl-aryl or heteroaryl, and, in alkyl and cycloalkyl, one or more CH2 groups may be replaced by —O—. The compounds of the formula (I) are valuable intermediates in the synthesis of PPAR agonists.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: January 24, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Claus-Jürgen Maier, Tobias Metzenthin, Joachim Graeser, Richard Bicker, Javier Manero
  • Publication number: 20040192956
    Abstract: A process is described for preparing compounds of formula (I) 1
    Type: Application
    Filed: March 18, 2004
    Publication date: September 30, 2004
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Claus-Jurgen Maier, Tobias Metzenthin, Joachim Graeser, Richard Bicker, Javier Manero
  • Patent number: 6710167
    Abstract: The present invention relates to an improved procedure for the chromatographic purification of insulins wherein a pressure-stable organic polymeric chromatography material is used as a stationary phase, and the mobile phase contains at least one water-miscible organic solvent and at least one buffer substance and the pH is from about 7 to about 11.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: March 23, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Werner Sievers, Richard Bicker, Dieter Desch, Jörg Von Eysmondt, Reinhold Keller, Frank Richard
  • Patent number: 5149716
    Abstract: The invention relates to insulin derivatives of the formula III ##STR1## in which R.sup.30 and R.sup.31 together are OH, or R.sup.30 is a radical of a neutral, genetically encodable L-amino acid and R.sup.31 is OH or a physiologically acceptable organic group of basic character having up to 50 carbon atoms, whose synthesis involves 0 to 3 .alpha.-amino acids and whose optional terminal carboxyl function can be present free, as an ester function, as an amide function, as a lactone or reduced to CH.sub.2 OH, and R.sup.A-1 is a radical of a genetically encodable L-amino acid, and physiologically acceptable salts of said insulin derivative of the formula III.
    Type: Grant
    Filed: October 26, 1990
    Date of Patent: September 22, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Karl Geisen, Richard Bicker
  • Patent number: 4900523
    Abstract: Cyanogen halides and/or phosgene are removed from waste gases by bringing the waste gases into intimate contact with an aqueous solution of at least one amine of the formula NR.sub.3 ; in the formula, 1 or 2 of the radicals R represent an alkanol or alkylamine group having 2 or 3 carbon atoms in each case, where H and/or C.sub.1 -C.sub.2 -alkyl is bound to the nitrogen of the amine group, and the remaining groups R are H or C.sub.1 -C.sub.4 -alkyl.
    Type: Grant
    Filed: February 17, 1989
    Date of Patent: February 13, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Richard Bicker, Manfred Schrod, Hans Militzer
  • Patent number: 4644057
    Abstract: The invention relates to a process for the cleavage of peptides and proteins at the methionyl bond using cyanogen chloride.
    Type: Grant
    Filed: November 7, 1985
    Date of Patent: February 17, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Richard Bicker, Gerhard Seipke
  • Patent number: 4332943
    Abstract: Pyridine is prepared by ammoxidation (=reaction with oxygen or an oxygen-containing gas and ammonia, if appropriate in the presence of steam) of cyclopentadiene in the presence of a tellurium-free silica gel catalyst, .gamma.-Al.sub.2 O.sub.3 catalyst and/or aluminum silicate catalyst, which is preferably also doped with transition metal oxides and/or the oxides of gallium and/or indium and, if appropriate, also contains trivial quantities of further customary additives. The surface area of the catalyst should be between about 75 and 800 m.sup.2 /g and the pore volume between about 0.2 and 2 cm.sup.3 /g, and the reaction temperature should be between about 200.degree. and 400.degree. C.The pyridine formed in the process is free from picolines and higher homologs.
    Type: Grant
    Filed: August 14, 1981
    Date of Patent: June 1, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Richard Bicker, Rudiger Erckel