Patents by Inventor Richard Bott
Richard Bott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12180522Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.Type: GrantFiled: May 24, 2021Date of Patent: December 31, 2024Assignee: Danisco US Inc.Inventors: Richard Bott, David A. Estell, Neeraj Pandey, Sina Pricelius, Jian Yao
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Patent number: 11946078Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.Type: GrantFiled: April 22, 2021Date of Patent: April 2, 2024Assignee: Danisco US Inc.Inventors: Neeraj Pandey, Sina Pricelius, Annapurna Sachan, Stepan Shipovskov, Richard Bott, Ajit Kumar Satapathy
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Publication number: 20210388334Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof, vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.Type: ApplicationFiled: May 24, 2021Publication date: December 16, 2021Inventors: RICHARD BOTT, DAVID A. ESTELL, NEERAJ PANDEY, SINA PRICELIUS, JIAN YAO
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Publication number: 20210309983Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.Type: ApplicationFiled: April 22, 2021Publication date: October 7, 2021Inventors: NEERAJ PANDEY, SINA PRICELIUS, ANNAPURNA SACHAN, STEPAN SHIPOVSKOV, RICHARD BOTT, AJIT KUMAR SATAPATHY
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Patent number: 11053488Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.Type: GrantFiled: December 14, 2017Date of Patent: July 6, 2021Assignee: DANISCO US INCInventors: Richard Bott, David A. Estell, Neeraj Pandey, Sina Pricelius, Jian Yao
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Publication number: 20200362324Abstract: Disclosed herein are mannanases from Paenibacillus sp., polynucleotides encoding the mannanases, compositions containing the mannanases, and methods of use thereof. Compositions containing mannanases are suitable for use as detergents and for cleaning fabrics and hard surfaces, as well as in a variety of other industrial applications.Type: ApplicationFiled: January 29, 2020Publication date: November 19, 2020Inventors: Christian D. Adams, Viktor Yuryevich Alekseyev, Richard Bott, David Marquez, Miles Christopher Scotcher, Jian Yao
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Patent number: 10774315Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes synthesize alpha-glucan products having increased molecular weight. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: GrantFiled: September 11, 2018Date of Patent: September 15, 2020Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLCInventors: Yougen Li, Ellen D. Semke, Mark S. Payne, Jared B. Parker, Susan Marie Hennessey, Slavko Kralj, Veli Alkan, Richard Bott
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Patent number: 10563187Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.Type: GrantFiled: March 28, 2018Date of Patent: February 18, 2020Assignee: Danisco US Inc.Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
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Publication number: 20190153417Abstract: Disclosed herein are mannanases from Paenibacillus sp., polynucleotides encoding the mannanases, compositions containing the mannanases, and methods of use thereof. Compositions containing mannanases are suitable for use as detergents and for cleaning fabrics and hard surfaces, as well as in a variety of other industrial applications.Type: ApplicationFiled: November 7, 2016Publication date: May 23, 2019Inventors: Christian D. Adams, Viktor Yuryevich Aleksetev, David Marquez, Miles Christopher Scotcher, Richard Bott, Jian Yao
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Publication number: 20190078062Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes synthesize alpha-glucan products having increased molecular weight. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: ApplicationFiled: September 11, 2018Publication date: March 14, 2019Inventors: YOUGEN LI, ELLEN D. SEMKE, MARK S. PAYNE, JARED B. PARKER, SUSAN MARIE HENNESSEY, SLAVKO KRALJ, VELI ALKAN, RICHARD BOTT
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Publication number: 20190002853Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.Type: ApplicationFiled: March 28, 2018Publication date: January 3, 2019Applicant: Danisco US Inc.Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
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Patent number: 9944913Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.Type: GrantFiled: August 5, 2016Date of Patent: April 17, 2018Assignee: Danisco US Inc.Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
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Publication number: 20170114336Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.Type: ApplicationFiled: August 5, 2016Publication date: April 27, 2017Applicant: Danisco US Inc.Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
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Patent number: 8809023Abstract: The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.Type: GrantFiled: August 18, 2010Date of Patent: August 19, 2014Assignee: Danisco US Inc.Inventors: Peter Edvard Degn, Richard Bott, Casper Willem Vroemen, Martijn Silvan Scheffers, Wolfgang Aehle
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Publication number: 20120149070Abstract: The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.Type: ApplicationFiled: August 18, 2010Publication date: June 14, 2012Applicants: DANISCO US INC., DANISCO A/SInventors: Peter Edvard Degn, Richard Bott, Casper Willem Vroemen, Martijn Silvan Scheffers, Wolfgang Aehle
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Publication number: 20070218115Abstract: A multi-layer dressing and controlled-release composition for topical application to a substrate include an emulsion and an active agent incorporated into the emulsion. The active agent includes a protein. A method of delivering the active agent to the substrate provides the emulsion and incorporates the active agent into the emulsion for delivery of the active agent to the substrate.Type: ApplicationFiled: October 27, 2004Publication date: September 20, 2007Inventors: Richard Bott, Kurt Brandstadt, Csilla Kollar, Thomas Lane, Donald Liles, Mae Saldjeno, Xavier Thomas
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Publication number: 20070190152Abstract: A method of providing an active agent topically to the skin is provided and includes providing a topical preparation having an internal phase and an external phase, wherein the internal phase is dispersed within the external phase. The internal phase includes at least one hydrophilic carrier, at least one hydrophilic component, and at least one active agent, and the external phase comprises a silicone matrix. The topical preparation is placed in contact with the skin of a patient such that the active agent is released from the silicone matrix topically onto the skin of the patient.Type: ApplicationFiled: February 20, 2007Publication date: August 16, 2007Inventors: Richard Bott, Mark Gebert, Paal Klykken, Isabelle Mazeaud, Xavier Thomas
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Publication number: 20070167344Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some embodiments, the present invention provides methods and compositions for generation of long chain peracids. Certain embodiments of the present invention find particular use in applications involving cleaning, bleaching and disinfecting.Type: ApplicationFiled: November 9, 2006Publication date: July 19, 2007Inventors: Neelam Amin, Richard Bott, Marguerite Cervin, Ayrookaran Poulose, Walter Weyler
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Publication number: 20070148199Abstract: Topical preparations for release of an active agent to the skin are provided. The preparations have an internal phase dispersed within an external phase. The internal phase includes a hydrophilic carrier and an enzyme active agent. The external phase comprises a silicone matrix.Type: ApplicationFiled: February 20, 2007Publication date: June 28, 2007Inventors: Richard Bott, Mark Gebert, Paal Klykken, Isabelle Mazeaud, Xavier Thomas
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Publication number: 20060084160Abstract: An enzyme multimer is provided which comprises a plurality of monomer units including a first monomer unit having enzymatic activity and a second monomer unit having enzymatic activity, wherein each of the first monomer unit and the second monomer unit comprise a cysteine residue and the cysteine residues of each monomer unit are covalently bound to each other through a disulfide bond to covalently attach the first monomer unit to the second monomer unit.Type: ApplicationFiled: December 22, 2004Publication date: April 20, 2006Inventors: Richard Bott, Christian Paech, Shan Wu