Patents by Inventor Richard Bott

Richard Bott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11946078
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: April 2, 2024
    Assignee: Danisco US Inc.
    Inventors: Neeraj Pandey, Sina Pricelius, Annapurna Sachan, Stepan Shipovskov, Richard Bott, Ajit Kumar Satapathy
  • Publication number: 20210388334
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof, vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: May 24, 2021
    Publication date: December 16, 2021
    Inventors: RICHARD BOTT, DAVID A. ESTELL, NEERAJ PANDEY, SINA PRICELIUS, JIAN YAO
  • Publication number: 20210309983
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: April 22, 2021
    Publication date: October 7, 2021
    Inventors: NEERAJ PANDEY, SINA PRICELIUS, ANNAPURNA SACHAN, STEPAN SHIPOVSKOV, RICHARD BOTT, AJIT KUMAR SATAPATHY
  • Patent number: 11053488
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: July 6, 2021
    Assignee: DANISCO US INC
    Inventors: Richard Bott, David A. Estell, Neeraj Pandey, Sina Pricelius, Jian Yao
  • Publication number: 20200362324
    Abstract: Disclosed herein are mannanases from Paenibacillus sp., polynucleotides encoding the mannanases, compositions containing the mannanases, and methods of use thereof. Compositions containing mannanases are suitable for use as detergents and for cleaning fabrics and hard surfaces, as well as in a variety of other industrial applications.
    Type: Application
    Filed: January 29, 2020
    Publication date: November 19, 2020
    Inventors: Christian D. Adams, Viktor Yuryevich Alekseyev, Richard Bott, David Marquez, Miles Christopher Scotcher, Jian Yao
  • Patent number: 10774315
    Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes synthesize alpha-glucan products having increased molecular weight. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: September 15, 2020
    Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
    Inventors: Yougen Li, Ellen D. Semke, Mark S. Payne, Jared B. Parker, Susan Marie Hennessey, Slavko Kralj, Veli Alkan, Richard Bott
  • Patent number: 10563187
    Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: February 18, 2020
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
  • Publication number: 20190153417
    Abstract: Disclosed herein are mannanases from Paenibacillus sp., polynucleotides encoding the mannanases, compositions containing the mannanases, and methods of use thereof. Compositions containing mannanases are suitable for use as detergents and for cleaning fabrics and hard surfaces, as well as in a variety of other industrial applications.
    Type: Application
    Filed: November 7, 2016
    Publication date: May 23, 2019
    Inventors: Christian D. Adams, Viktor Yuryevich Aleksetev, David Marquez, Miles Christopher Scotcher, Richard Bott, Jian Yao
  • Publication number: 20190078062
    Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes synthesize alpha-glucan products having increased molecular weight. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.
    Type: Application
    Filed: September 11, 2018
    Publication date: March 14, 2019
    Inventors: YOUGEN LI, ELLEN D. SEMKE, MARK S. PAYNE, JARED B. PARKER, SUSAN MARIE HENNESSEY, SLAVKO KRALJ, VELI ALKAN, RICHARD BOTT
  • Publication number: 20190002853
    Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
    Type: Application
    Filed: March 28, 2018
    Publication date: January 3, 2019
    Applicant: Danisco US Inc.
    Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
  • Patent number: 9944913
    Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: April 17, 2018
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
  • Publication number: 20170114336
    Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
    Type: Application
    Filed: August 5, 2016
    Publication date: April 27, 2017
    Applicant: Danisco US Inc.
    Inventors: Wolfgang Aehle, Piet Van Solingen, Martijn Scheffers, Richard Bott
  • Patent number: 8809023
    Abstract: The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: August 19, 2014
    Assignee: Danisco US Inc.
    Inventors: Peter Edvard Degn, Richard Bott, Casper Willem Vroemen, Martijn Silvan Scheffers, Wolfgang Aehle
  • Publication number: 20120149070
    Abstract: The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
    Type: Application
    Filed: August 18, 2010
    Publication date: June 14, 2012
    Applicants: DANISCO US INC., DANISCO A/S
    Inventors: Peter Edvard Degn, Richard Bott, Casper Willem Vroemen, Martijn Silvan Scheffers, Wolfgang Aehle
  • Publication number: 20070218115
    Abstract: A multi-layer dressing and controlled-release composition for topical application to a substrate include an emulsion and an active agent incorporated into the emulsion. The active agent includes a protein. A method of delivering the active agent to the substrate provides the emulsion and incorporates the active agent into the emulsion for delivery of the active agent to the substrate.
    Type: Application
    Filed: October 27, 2004
    Publication date: September 20, 2007
    Inventors: Richard Bott, Kurt Brandstadt, Csilla Kollar, Thomas Lane, Donald Liles, Mae Saldjeno, Xavier Thomas
  • Publication number: 20070190152
    Abstract: A method of providing an active agent topically to the skin is provided and includes providing a topical preparation having an internal phase and an external phase, wherein the internal phase is dispersed within the external phase. The internal phase includes at least one hydrophilic carrier, at least one hydrophilic component, and at least one active agent, and the external phase comprises a silicone matrix. The topical preparation is placed in contact with the skin of a patient such that the active agent is released from the silicone matrix topically onto the skin of the patient.
    Type: Application
    Filed: February 20, 2007
    Publication date: August 16, 2007
    Inventors: Richard Bott, Mark Gebert, Paal Klykken, Isabelle Mazeaud, Xavier Thomas
  • Publication number: 20070167344
    Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some embodiments, the present invention provides methods and compositions for generation of long chain peracids. Certain embodiments of the present invention find particular use in applications involving cleaning, bleaching and disinfecting.
    Type: Application
    Filed: November 9, 2006
    Publication date: July 19, 2007
    Inventors: Neelam Amin, Richard Bott, Marguerite Cervin, Ayrookaran Poulose, Walter Weyler
  • Publication number: 20070148199
    Abstract: Topical preparations for release of an active agent to the skin are provided. The preparations have an internal phase dispersed within an external phase. The internal phase includes a hydrophilic carrier and an enzyme active agent. The external phase comprises a silicone matrix.
    Type: Application
    Filed: February 20, 2007
    Publication date: June 28, 2007
    Inventors: Richard Bott, Mark Gebert, Paal Klykken, Isabelle Mazeaud, Xavier Thomas
  • Publication number: 20060084160
    Abstract: An enzyme multimer is provided which comprises a plurality of monomer units including a first monomer unit having enzymatic activity and a second monomer unit having enzymatic activity, wherein each of the first monomer unit and the second monomer unit comprise a cysteine residue and the cysteine residues of each monomer unit are covalently bound to each other through a disulfide bond to covalently attach the first monomer unit to the second monomer unit.
    Type: Application
    Filed: December 22, 2004
    Publication date: April 20, 2006
    Inventors: Richard Bott, Christian Paech, Shan Wu
  • Publication number: 20060083776
    Abstract: A multi-layer dressing and controlled-release composition for topical application to a substrate include an emulsion and an active agent incorporated into the emulsion. The active agent includes a protein. A method of delivering the active agent to the substrate provides the emulsion and incorporates the active agent into the emulsion for delivery of the active agent to the substrate. Multi-layer dressings and methods particularly suited for management of wound exudate and effective debridement of wound eschar.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 20, 2006
    Inventors: Richard Bott, Kurt Brandstadt, Csilla Kollar, Thomas Lane, Donald Liles, Mae Saldjeno, Xavier Thomas, Kevin Murphy, Gerald Schalau