Patents by Inventor Richard Bringham
Richard Bringham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190021308Abstract: The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.Type: ApplicationFiled: September 13, 2018Publication date: January 24, 2019Applicant: TransMedics, Inc.Inventors: Waleed H. HASSANEIN, Tamer I. KHAYAL, Ahmed ELBETANONY, Jeff BARNES, Greg RITCHIE, Richard BRINGHAM, Mark ANDERSON, John SULLIVAN
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Patent number: 10076112Abstract: The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.Type: GrantFiled: June 2, 2015Date of Patent: September 18, 2018Assignee: TRANSMEDIC, INC.Inventors: Waleed H. Hassanein, Tamer I. Khayal, Ahmed Elbetanony, Jeff Barnes, Greg Ritchie, Richard Bringham, Mark Anderson, John Sullivan
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Patent number: 9814230Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: GrantFiled: April 8, 2008Date of Patent: November 14, 2017Assignee: TRANSMEDICS, INC.Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
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Publication number: 20170064943Abstract: The invention provides, in various embodiments, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to aortic cannulas for use in perfusion systems to return perfusate to the heart or delivering perfusate from the heart while the organ is sustained ex vivo at physiologic or near-physiologic conditions.Type: ApplicationFiled: September 7, 2016Publication date: March 9, 2017Inventors: Greg RITCHIE, Vincent LAMBERT, II, Richard BRINGHAM, John SULLIVAN, Waleed H. HASSANEIN
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Publication number: 20160374332Abstract: Electrode systems have been developed for use in perfusion systems to measure the electrical activity of an explanted heart and to provide defibrillation energy as necessary. The perfusion systems maintain the heart in a heating state at, or near, normal physiological conditions; circulating oxygenated, nutrient enriched perfusion fluid to the heart at or near physiological temperature, pressure and flow rate. These systems include a pair of electrodes that are placed epicardially on the right atrium and left ventricle of the explanted heart, as well as an electrode placed in the aortic blood path.Type: ApplicationFiled: July 11, 2016Publication date: December 29, 2016Applicant: TransMedics, IncInventors: Waleed H. HASSANEIN, Ahmed ELBETANONY, Richard BRINGHAM, Robert HAVENER, Vincent LAMBERT, II, Burt OCHS
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Patent number: 9516875Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: GrantFiled: February 12, 2013Date of Patent: December 13, 2016Assignee: TRANSMEDICS, INC.Inventors: Robert Fishman, Robert Havener, Ihab A. Fattah, Anas Abdelazim, Scott Newell, Thomas H. Bishop, Tamer I. Khayal, Stanley Kyi, Ron Taylor, Jr., Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed H. Hassanein
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Patent number: 9462802Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: GrantFiled: April 8, 2008Date of Patent: October 11, 2016Assignee: TRANSMEDICS, INC.Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
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Patent number: 9457179Abstract: Electrode systems have been developed for use in perfusion systems to measure the electrical activity of an explanted heart and to provide defibrillation energy as necessary. The perfusion systems maintain the heart in a beating state at, or near, normal physiological conditions; circulating oxygenated, nutrient enriched perfusion fluid to the heart at or near physiological temperature, pressure and flow rate. These systems include a pair of electrodes that are placed epicardially on the right atrium and left ventricle of the explanted heart, as well as an electrode placed in the aortic blood path.Type: GrantFiled: July 6, 2007Date of Patent: October 4, 2016Assignee: TRANSMEDICS, INC.Inventors: Waleed Hassanein, Ahmed Elbetanony, Richard Bringham, Robert Havener, Vincent Lambert, II, Burt Ochs
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Publication number: 20160095308Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.Type: ApplicationFiled: November 12, 2015Publication date: April 7, 2016Inventors: Waleed H. HASSANEIN, Richard BRINGHAM, Giovanni CECERE, Tamer I. KHAYAL, Ronald TAYLOR, Hossam ALGAMIL
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Patent number: 9301519Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.Type: GrantFiled: October 7, 2005Date of Patent: April 5, 2016Assignee: TRANSMEDICS, INC.Inventors: Waleed Hassanein, Richard Bringham, Giovanni Cecere, Ahmed Elbetanony, Robert Fishman, Larry Goff, Tamer Khayal, Stanley Kyi, Scott Newell, Burt Ochs, Dennis Sousa, Ronald Taylor, Jonathan Rourke, Hossam Algamil, David Carpenter, Robert Havner
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Patent number: 9247728Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: GrantFiled: April 8, 2008Date of Patent: February 2, 2016Assignee: TRANSMEDICS, INC.Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
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Patent number: 9215867Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.Type: GrantFiled: October 7, 2005Date of Patent: December 22, 2015Assignee: TRANSMEDICS, INC.Inventors: Waleed Hassanein, Richard Bringham, Giovanni Cecere, Tamer Khayal, Ronald Taylor, Hossam Algamil
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Publication number: 20150342177Abstract: The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.Type: ApplicationFiled: June 2, 2015Publication date: December 3, 2015Inventors: Waleed H. HASSANEIN, Tamer I. KHAYAL, Ahmed ELBETANONY, Jeff BARNES, Greg RITCHIE, Richard BRINGHAM, Mark ANDERSON, John SULLIVAN
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Patent number: 8585380Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.Type: GrantFiled: October 7, 2005Date of Patent: November 19, 2013Assignee: Transmedics, Inc.Inventors: Waleed Hassanein, Richard Bringham, Robert Fishman, Larry Goff, Stanley Kyi, Jonathan Rourke, Dmitri Menn, David Carpenter, Robert Havner
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Patent number: 8465970Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.Type: GrantFiled: October 7, 2005Date of Patent: June 18, 2013Assignee: TransMedics, Inc.Inventors: Waleed Hassanein, Richard Bringham, Giovanni Cecere, Ahmed Elbetanony, Robert Fishman, Larry Goff, Tamer Khayal, Stanley Kyi, Scott Newell, Burt Ochs, Dennis Sousa, Ronald Taylor, Jonathan Rourke, Hossam Algamil, David Carpenter, Robert Havner, Dmitri Menn
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Patent number: 8420380Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: GrantFiled: April 8, 2008Date of Patent: April 16, 2013Assignee: TransMedics, Inc.Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
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Patent number: 7651835Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.Type: GrantFiled: October 7, 2005Date of Patent: January 26, 2010Assignee: TransMedics, Inc.Inventors: Waleed Hassanein, Richard Bringham, Giovanni Cecere, Robert Fishman, Larry Goff, Tamer Khayal, Stanley Kyi, Burt Ochs, Scott Newell, Ronald Taylor, Hossam Algamil, Thomas Bishop, Robert Havner, Dmitri Menn
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Publication number: 20090197324Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: ApplicationFiled: April 8, 2008Publication date: August 6, 2009Inventors: Robert FISHMAN, Robert HAVENER, Ihab Abdel FATTAH, Anas ABDELAZIM, Scott NEWELL, Tom BISHOP, Tamer KHAYAL, Stanley KYI, Ron TAYLOR, Doug HARRIOTT, Matthew DE REMER, Paul MURRAY, John SULLIVAN, Mark ANDERSON, Richard BRINGHAM, Michael VAN DRIEL, Waleed Hassanein
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Publication number: 20090197292Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: ApplicationFiled: April 8, 2008Publication date: August 6, 2009Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
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Publication number: 20090197241Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.Type: ApplicationFiled: April 8, 2008Publication date: August 6, 2009Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein