Patents by Inventor Richard Burack

Richard Burack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Predicting Clinical Outcome of Chronic Lymphocytic Leukemia
    Publication number: 20150056171
    Abstract: Provided are methods of predicting the outcome of a chronic lymphocytic leukemia (CLL) in a subject. The methods comprise performing a polymerase chain reaction assay for an IGH locus on a nucleic acid from a biological sample from a subject with CLL, wherein the PCR assay amplifies a non-coding region of the IGH locus, sequencing a product from the PCR assay, and determining a level of mutation in the non-coding region of the IGH locus. An increased level of mutation in the non-coding region as compared to a control indicates a positive outcome for the subject with CLL. A decreased level or no mutation in the non-coding region as compared to a control indicates a poor outcome for the subject with CLL.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 26, 2015
    Applicant: University of Rochester
    Inventors: Richard Burack, Jan Spence