Patents by Inventor Richard C. Deth

Richard C. Deth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying and determining the effectiveness of therapeutic processes or agents for the treatment of schizophrenia and related disorders
    Patent number: 6773892
    Abstract: Methods for detecting schizophrenia or related neuropsychiatric disorders based on modifications of the contribution of the D4 receptor to phospholipid methylation levels are described herein. Individuals with schizophrenia or related neuropsychiatric disorders have a deficiency in phospholipid methylation activity compared with normal individuals. Methods for screening therapeutic processes or agents for use in treatment of schizophrenia or related neuropsychiatric disorders are also described.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: August 10, 2004
    Assignee: Northeastern University
    Inventor: Richard C. Deth
  • Methods and materials for the diagnosis and treatment of schizophrenia and related disorders
    Patent number: 6080549
    Abstract: Methods for detecting schizophrenia or depression based on modifications of the contribution of the D.sub.4 receptor to phospholipid methylation levels are described herein. Individuals with schizophrenia or depression have a deficiency in phospholipid methylation activity compared with normal individuals. Methods for screening therapeutic processes or agents for use in treatment of schizophrenia or related neuropsychiatric disorders are also described.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: June 27, 2000
    Assignee: Northeastern University
    Inventor: Richard C. Deth
  • Compositions and methods for diagnosing schizophrenia
    Patent number: 5738998
    Abstract: Methods and compositions for detecting schizophrenia based on modification of the dopamine D.sub.4 receptor by addition of an adenosyl group to methionine #313 via methionine adenosyltransferase are described herein. Individuals with schizophrenia have a deficiency in methionine adenosyltransferase activity and a lower amount of modified dopamine D.sub.4 receptor than normal individuals. Methods for screening therapeutic processes, agents and drugs for use in treatment of schizophrenia are also described.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: April 14, 1998
    Inventor: Richard C. Deth
  • Compositions and methods for diagnosing schizophrenia
    Patent number: 5686255
    Abstract: Methods and compositions for detecting schizophrenia based on modification of the dopamine D.sub.4 receptor by addition of an adenosyl group to methionine #313 via methionine adenosyltransferase are described herein. Individuals with schizophrenia have a deficiency in methionine adenosyltransferase activity and a lower amount of modified dopamine D.sub.4 receptor than normal individuals. Methods for screening therapeutic processes, agents and drugs for use in treatment of schizophrenia are also described.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: November 11, 1997
    Inventor: Richard C. Deth