Patents by Inventor Richard C. Gregory

Richard C. Gregory has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-TGF-BETA ANTIBODIES AND THEIR USE
    Publication number: 20220195026
    Abstract: The invention provides an improved pan-TGF-? antibody for treatment of conditions that are mediated by TGF-?, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 23, 2022
    Applicant: SANOFI
    Inventors: Gary Shapiro, Kevin Brower, Patrick Finn, Richard C. Gregory, Rao Koduri, Feng Liu, Natalia Malkova, Parminder Mankoo, Jack R. Pollard, Huawei Qiu, Joachim Theilhaber, Christopher Winter, Marcella Yu
  • Anti-TGF-beta antibodies and their use
    Patent number: 11242384
    Abstract: The invention provides an improved pan-TGF-? antibody for treatment of conditions that are mediated by TGF-?, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: February 8, 2022
    Assignee: SANOFI
    Inventors: Gary Shapiro, Kevin Brower, Patrick Finn, Richard C. Gregory, Rao Koduri, Feng Liu, Natalia Malkova, Parminder Mankoo, Jack R. Pollard, Huawei Qiu, Joachim Theilhaber, Christopher Winter, Marcella Yu
  • COMBINATION THERAPIES AGAINST CANCER TARGETING CD38 AND TGF-BETA
    Publication number: 20210155708
    Abstract: The present disclosure relates to combination cancer therapies targeting CD38 and TGF-? using antibodies specific for these targets. Also provided are compositions useful in the therapies.
    Type: Application
    Filed: July 10, 2019
    Publication date: May 27, 2021
    Inventors: Francisco ADRIAN, Richard C. GREGORY, Gary SHAPIRO, Helgi VAN DE VELDE
  • ANTI-TGF-BETA ANTIBODIES AND THEIR USE
    Publication number: 20200399358
    Abstract: The invention provides an improved pan-TGF-? antibody for treatment of conditions that are mediated by TGF-?, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
    Type: Application
    Filed: July 16, 2020
    Publication date: December 24, 2020
    Inventors: Gary Shapiro, Kevin Brower, Patrick Finn, Richard C. Gregory, Rao Koduri, Feng Liu, Natalia Malkova, Parminder Mankoo, Jack R. Pollard, Huawei Qiu, Joachim Theilhaber, Christopher Winter, Marcella Yu
  • Anti-TGF-? antibodies and their use
    Patent number: 10766955
    Abstract: The invention provides an improved pan-TGF-? antibody for treatment of conditions that are mediated by TGF-?, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: September 8, 2020
    Assignee: SANOFI
    Inventors: Gary Shapiro, Kevin Brower, Patrick Finn, Richard C. Gregory, Rao Koduri, Feng Liu, Natalia Malkova, Parminder Mankoo, Jack R. Pollard, Huawei Qiu, Joachim Theilhaber, Christopher Winter, Marcella Yu
  • Treatment of myocardial infarction using TGF-? antagonists
    Patent number: 10633437
    Abstract: Disclosed herein is a method of treating a patient suffering a myocardial infarction, particularly an acute myocardial infarction, or of reducing an adverse consequence of a myocardial infarction in a patient comprising administering an antagonist of TGF-? to the patient during the acute stage of the myocardial infarction.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: April 28, 2020
    Assignee: GENZYME CORPORATION
    Inventors: Geoffrey Y. Akita, Scott Lonning, Richard C Gregory, Jr., Amelia B Kudej
  • ANTI-TGF-BETA ANTIBODIES AND THEIR USE
    Publication number: 20180244763
    Abstract: The invention provides an improved pan-TGF-? antibody for treatment of conditions that are mediated by TGF-?, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
    Type: Application
    Filed: January 19, 2018
    Publication date: August 30, 2018
    Applicant: SANOFI
    Inventors: Gary Shapiro, Kevin Brower, Patrick Finn, Richard C. Gregory, Rao Koduri, Feng Liu, Natalia Malkova, Parminder Mankoo, Jack R. Pollard, Huawei Qiu, Joachim Theilhaber, Christopher Winter, Marcella Yu
  • TREATMENT OF MYOCARDIAL INFARCTION USING TGF BETA ANTAGONISTS
    Publication number: 20170233465
    Abstract: Disclosed herein is a method of treating a patient suffering a myocardial infarction, particularly an acute myocardial infarction, or of reducing an adverse consequence of a myocardial infarction in a patient comprising administering an antagonist of TGF-? to the patient during the acute stage of the myocardial infarction.
    Type: Application
    Filed: December 12, 2016
    Publication date: August 17, 2017
    Applicant: Genzyme Corporation
    Inventors: Geoffrey Y. AKITA, Scott Lonning, Richard C. Gregory, JR., Amelia B. Kudej