Patents by Inventor Richard C. Hutchinson

Richard C. Hutchinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthases and accessory proteins, and uses thereof
    Patent number: 7671190
    Abstract: The invention relates to recombinant polyketide synthase enzymes, polyketide modifying proteins, and other proteins involved in polyketide biosynthesis or function. The invention provides domains of geldanamycin and herbimycin polyketide synthases, polynucleotides that encode such enzymes, and to host cells in which such encoding polynucleotides can be advantageously expressed.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: March 2, 2010
    Assignee: Kosan Biosciences Incorporation
    Inventors: Richard C. Hutchinson, Ralph C. Reid, Zhihao Hu, Andreas Rascher, Andreas Schirmer, Robert McDaniel
  • Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthase and accessory proteins, and uses thereof
    Patent number: 7189549
    Abstract: The invention relates to recombinant polyketide synthase enzymes, polyketide modifying proteins, and other proteins involved in polyketide biosynthesis or function. The invention provides domains of geldanamycin and herbimycin polyketide synthases, polynucleotides that encode such enzymes, and to host cells in which such encoding polynucleotides can be advantageously expressed.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: March 13, 2007
    Assignee: Kosan Biosciences, Inc.
    Inventors: Richard C. Hutchinson, Ralph C. Reid, Zhihao Hu, Andreas Rascher, Andreas Schirmer, Robert McDaniel
  • Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthase and accessory proteins, and uses thereof
    Publication number: 20040077058
    Abstract: The invention relates to recombinant polyketide synthase enzymes, polyketide modifying proteins, and other proteins involved in polyketide biosynthesis or function. The invention provides domains of geldanamycin and herbimycin polyketide synthases, polynucleotides that encode such enzymes, and to host cells in which such encoding polynucleotides can be advantageously expressed.
    Type: Application
    Filed: June 13, 2003
    Publication date: April 22, 2004
    Inventors: Richard C. Hutchinson, Ralph C. Reid, Zhihao Hu, Andreas Rascher, Andreas Schirmer, Robert McDaniel
  • Plasmids for polyketide production
    Publication number: 20030077759
    Abstract: Streptomyces plasmids comprising two SCP2-derived replicons, at least one of which is derived from SCP2@, have a higher copy number and exhibit greater stability than SCP2- or SCP2*-derived plasmids having only a single SCP2-derived replicon and can be used to increase gene expression, relative to the latter plasmids, in host cells.
    Type: Application
    Filed: April 19, 2002
    Publication date: April 24, 2003
    Inventors: Zhihao Hu, Richard C. Hutchinson