Abstract: A method for the measurement and analysis of skin fluorescence across multiple subjects. The method includes illuminating each subject with an excitation wavelength, detecting a peak fluorescence level within a corresponding emission wavelength range, determining relative levels of skin glycation for each subject, and evaluating the efficacy of a skin treatment based on the relative levels of skin glycation. The method can include ranking and normalizing the peak fluorescence levels for each subject, and the method is suitable for use in placebo-controlled studies of anti-glycation skin therapies.

Abstract: Devices and methods for reproducibly positioning a subject are described. A device may include a first parallax bar assembly having a first wire and a second wire spaced a first distance and parallel to the first wire, and a second parallax bar assembly having a third wire and a fourth wire spaced a second distance and parallel to the third wire. The first and second wires are substantially perpendicular to the third and fourth wires, and an imaginary straight line intersects the first, second, third, and fourth wires. Some devices may include a chair and a headrest for positioning a subject.

Abstract: A method for the measurement and analysis of skin fluorescence across multiple subjects. The method includes illuminating each subject with an excitation wavelength, detecting a peak fluorescence level within a corresponding emission wavelength range, determining relative levels of skin glycation for each subject, and evaluating the efficacy of a skin treatment based on the relative levels of skin glycation. The method can include ranking and normalizing the peak fluorescence levels for each subject, and the method is suitable for use in placebo-controlled studies of anti-glycation skin therapies.

Abstract: A method of coupling rules to a data domain of an object-oriented computer program. During run time, the coupling permits the computer to use rules to directly access user-defined objects for both the matching and the action phases of the inferencing process, Inferencing is implemented with an inference class object and user-defined class object are derived from a working memory element class.

Abstract: A method of coupling rules to a data domain of an object-oriented computer program. During run time, the coupling permits the computer to use rules to directly access user-defined objects for both the matching and the action phases of the inferencing process. Inferencing is implemented with an inference class object and user-defined class object are derived from a working memory element class.

Abstract: A disposable medicinal application apparatus for use in the administration of a medicinal fluid comprises sealed flexible bag means at least partially filled with a quantity of the fluid to be applied. The apparatus has a neck piece freely enclosed within the sealed bag means, the neck piece being manipulable against the interior surface of a portion of the bag means and the bag wall being stretched over the neck piece. A separate applicator member has a passage in communication with discharge means. Cooperative locking and lockable means are formed on the applicator member and the neck piece, respectively, to allow the applicator member to be snap-fitted and locked to the neck piece, with the bore of the neck piece and the passage of the applicator member in alignment. A portion of the bag wall is compressed between the exterior surface of the neck piece and the interior surface of the applicator member to form a fluid-tight seal therebetween.