Abstract: The inventive subject matter is directed to an artificial intelligence intra-operative surgical guidance system and method of use. The artificial intelligence intra-operative surgical guidance system is made of a computer executing one or more automated artificial intelligence models trained on data layer datasets collections to calculate surgical decision risks, and provide intra-operative surgical guidance; and a display configured to provide visual guidance to a user.

Abstract: An apparatus including a superstructure comprising: a vacuum collection pod comprising a vessel with a first opening near the base, a second opening near the top of the vessel for a vacuum system, and a third opening near the top of the cylindrical vessel for a hose delivering solid and liquid materials; a rotary airlock valve coupled to the first opening; a vacuum system attached to the superstructure, wherein the inlet of the vacuum system is in fluid communication with the second opening near the top of the vessel using a vacuum line; and a solids separator below the rotary airlock valve, the solids separator comprising a drill cuttings dryer, an effluent tank configured to collect effluent from the solids separator, and a centrifugal pump configured to remove the effluent from the effluent tank. Methods of treating drill cuttings include the use of the apparatus.

Abstract: An apparatus including a superstructure comprising: a vacuum collection pod comprising a vessel with a first opening near the base, a second opening near the top of the vessel for a vacuum system, and a third opening near the top of the cylindrical vessel for a hose delivering solid and liquid materials; a rotary airlock valve coupled to the first opening; a vacuum system attached to the superstructure, wherein the inlet of the vacuum system is in fluid communication with the second opening near the top of the vessel using a vacuum line; and a solids separator below the rotary airlock valve, the solids separator comprising a drill cuttings dryer, an effluent tank configured to collect effluent from the solids separator, and a centrifugal pump configured to remove the effluent from the effluent tank. Methods of treating drill cuttings include the use of the apparatus.

Abstract: The present invention relates to Anti-Mullerian Hormone (AMH) neutralizing antibodies and their use in the field of reproduction.

Abstract: The present invention relates to Anti-Mullerian Hormone (AMH) neutralizing antibodies and their use in the field of reproduction.

Abstract: The present invention relates to soluble monomeric Anti-Mullerian Hormone Receptor type II (AMHRII) fusion proteins and uses thereof, in particular for detection or quantification of the bioactive cleaved form of Anti-Müillerian Hormone in a sample. In particular, the present invention relates to a soluble monomeric AMHRII fusion protein wherein one AMHRII extracellular domain is fused to a heterologous polypeptide. A further aspect of the present invention relates to a method for detecting or quantifying the presence of bioactive cleaved AMH in a sample, said method comprising contacting the sample with a soluble monomeric AMHRII fusion protein of the invention.

Abstract: The present invention relates to soluble monomeric Anti-Mullerian Hormone Receptor type II (AMHRII) fusion proteins and uses thereof, in particular for detection or quantification of the bioactive cleaved form of Anti-Müillerian Hormone in a sample. In particular, the present invention relates to a soluble monomeric AMHRII fusion protein wherein one AMHRII extracellular domain is fused to a heterologous polypeptide. A further aspect of the present invention relates to a method for detecting or quantifying the presence of bioactive cleaved AMH in a sample, said method comprising contacting the sample with a soluble monomeric AMHRII fusion protein of the invention.

Abstract: A cleaning and separating system is provided for cleaning tanks (such as crude oil storage tanks), and other containers or enclosures. The cleaning and separating system invention fits within a limited space having a relatively small foot-print; preferably an 8 foot tall by 8 foot wide by 10 foot deep shipping container. Generally, wash fluid is sprayed into a vessel to be cleaned in order to form a slurry comprising liquid and solids. The slurry is then transferred to a cleaning and separating apparatus, where it is separated into liquid and solid components. The solids can be disposed of, while the liquids can be reclaimed.

Abstract: A cleaning and separating system is provided for cleaning tanks (such as crude oil storage tanks), and other containers or enclosures. The cleaning and separating system invention fits within a limited space having a relatively small foot-print; preferably an 8 foot tall by 8 foot wide by 10 foot deep shipping container. Although components can be interchanged or modified to fit particular applications, the cleaning and separating system can include a heated working tank having an agitator and a heating element, a centrifuge feed pump, a separation device (such as, for example, de-sander, de-silter, centrifuge, shale shaker, hydrocyclone or other similar apparatus), a liquid effluent tank, an oil and water discharge pump, an auger, a clean water tank, a high-pressure sprayer and/or a rotating nozzle.

Abstract: Proteins which are upregulated in injured or regenerating tissues, as well as the DNA encoding these proteins, are disclosed, as well as therapeutic compositions and methods of treatment encompassing these compounds.

Abstract: The invention relates generally to genes that encode proteins that inhibit axonal growth. The invention relates specifically to genes encoding NgR protein homologs in humans and mice. The invention also includes compositions and methods for modulating the expression and activity of Nogo and the NgR proteins. Specifically, the invention includes peptides, proteins and antibodies that block Nogo-mediated inhibition of axonal extension. The compositions and methods of the invention are useful in the treatment of cranial or cerebral trauma, spinal cord injury, stroke or a demyelinating disease.

Abstract: Proteins which are upregulated in injured or regenerating tissues, as well as the DNA encoding these proteins, are disclosed, as well as therapeutic compositions and methods of treatment encompassing these compounds.

Abstract: The disclosure provides methods and compositions for the evaluation of neuropathic pain and neurotrophic or other activity of a drug or drug candidate. In the disclosed methods, expression of certain gene(s) in tissue extracts from skin biopsies serves as a proxy of a relevant endpoint.

Abstract: Fusion proteins comprising the TGF-beta Type II receptor linked to a portion of an immunoglobulin constant chain are described. Also described are methods of using the fusion proteins of the invention to treat a variety of fibroproliferative disorders.

Abstract: Proteins which are upregulated in injured or regenerating tissues, as well as the DNA encoding these proteins, are disclosed, as well as therapeutic compositions and methods of treatment encompassing these compounds.

Abstract: Nucleotide and amino acid sequences are provided for compounds which promote tissue growth, as well as methods for modulating tissue growth, for imaging tissues and organs, and for treating patients.

Abstract: The invention relates generally to genes that encode proteins that inhibit axonal growth. The invention relates specifically to genes encoding NgR protein homologs in humans and mice. The invention also includes compositions and methods for modulating the expression and activity of Nogo and the NgR proteins. Specifically, the invention includes peptides, proteins and antibodies that block Nogo-mediated inhibition of axonal extension. The compositions and methods of the invention are useful in the treatment of cranial or cerebral trauma, spinal cord injury, stroke or a demyelinating disease.

Abstract: Fusion proteins comprising a variant form of TGF-beta Type II receptor linked to a portion of an immunoglobulin constant chain are described. Also described are methods of using the fusion proteins of the invention to treat a variety of fibroproliferative disorders.