Abstract: Training a neural network processor is described for providing diagnostic information of a controlled liquid chromatography pump unit. The training includes executing a sequence of operations wherein the neural network processor is trained with input signals obtained from a simulated version of the controlled liquid chromatography pump unit and associated sensors, while modifying the simulated version of the liquid chromatography pump unit to a pump fault simulation signal. Dependent on a value of the pump fault simulation signal, the simulated version of the liquid chromatography pump unit simulates operation of the liquid chromatography pump unit free from faults or the operation thereof with one or more pump faults.

Abstract: A high or ultra high performance liquid chromatography pump has a plunger rod extending in an axial direction into a pump chamber through a plunger passage. The plunger rod is reciprocally movable in the axial direction into the pump chamber and back. An outlet channel extends through the pump head between an outlet port and the pump chamber and an inlet channel extends through the pump head between an inlet port and the pump chamber. The pump head has a pump head block and a pressure sensor body. A tubular portion of the pump head block projects into the pressure sensor body. The outlet channel has at least one diversion conduit portion at least partially bounded by the tubular portion of the pump head block, the diversion conduit portion of the outlet channel extending from said pump chamber in said axial direction.

Abstract: A high or ultra high performance liquid chromatography pump has a plunger rod extending in an axial direction into a pump chamber through a plunger passage. The plunger rod is reciprocally movable in the axial direction into the pump chamber and back. An outlet channel extends through the pump head between an outlet port and the pump chamber and an inlet channel extends through the pump head between an inlet port and the pump chamber. The pump head has a pump head block and a pressure sensor body. A tubular portion of the pump head block projects into the pressure sensor body. The outlet channel has at least one diversion conduit portion at least partially bounded by the tubular portion of the pump head block, the diversion conduit portion of the outlet channel extending from said pump chamber in said axial direction.