Patents by Inventor Richard Chen

Richard Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230005111
    Abstract: A hybrid-distance adversarial patch generator can be trained to generate a hybrid adversarial patch effective at multiple distances. The hybrid patch can be inserted into multiple sample images, each depicting an object, to simulate inclusion of the hybrid patch at multiple distances. The multiple sample images can then be used to train an object detection model to detect the objects.
    Type: Application
    Filed: June 30, 2021
    Publication date: January 5, 2023
    Inventors: Quanfu Fan, Sijia Liu, Richard Chen, Rameswar Panda
  • Patent number: 11544611
    Abstract: Techniques regarding quantum computation of molecular excited states are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise an initialization component that can categorize a plurality of excited operators from a mapped qubit Hamiltonian into sectors based on a commutation property of the plurality of excited operators with a symmetry from the mapped qubit Hamiltonian. The computer executable components can also comprise a matrix component that can generate an equation of motion matrix from an excited operator from the plurality of excited operators based on the sectors categorized by the initialization component.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: January 3, 2023
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Richard Chen, Antonio Mezzacapo, Marco Pistoia, Pauline Ollitrault, Ivano Tavernelli, Jay M. Gambetta
  • Publication number: 20220414511
    Abstract: A hybrid classical-quantum computing device to execute a quantum circuit corresponding to a variational problem, is configured. The configuring further comprises causing the hybrid classical-quantum computing device to execute the quantum circuit by performing an adiabatic progression operation, wherein the adiabatic progression operation comprises increasing the difficulty of the variational problem from a simplified version of the problem to the variational problem.
    Type: Application
    Filed: April 26, 2022
    Publication date: December 29, 2022
    Applicant: International Business Machines Corporation
    Inventors: Don Greenberg, Marco Pistoia, Richard Chen, Giacomo Nannicini
  • Publication number: 20220414510
    Abstract: A hybrid classical-quantum computing device to execute a quantum circuit corresponding to a variational problem, is configured. The configuring further comprises causing the hybrid classical-quantum computing device to execute the quantum circuit by performing an adiabatic progression operation, wherein the adiabatic progression operation comprises increasing the difficulty of the variational problem from a simplified version of the problem to the variational problem.
    Type: Application
    Filed: April 26, 2022
    Publication date: December 29, 2022
    Applicant: International Business Machines Corporation
    Inventors: Don Greenberg, Marco Pistoia, Richard Chen, Giacomo Nannicini
  • Publication number: 20220392577
    Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
    Type: Application
    Filed: August 4, 2022
    Publication date: December 8, 2022
    Inventors: Jason Harris, Mark R. Pratt, John West, Richard Chen, Ming Li
  • Patent number: 11514079
    Abstract: A distributed database management system comprises a plurality of peers and maintains data on behalf of a plurality of clients. Upon receiving a request to access data, the distributed database management system identifies, from among the plurality of peers, a set of peers associated with the client issuing the request. The distributed database management system provides, to the client, a list of the set of identified peers. Access to data maintained by the distributed database system is based, at least in part, on connections between the client and the set of identified peers.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: November 29, 2022
    Assignee: Amazon Technologies, Inc.
    Inventors: Almero Gouws, Derek William Richard Chen-Becker, Haifeng He, Varsha Ganesh, Akshat Vig, Benny Tran
  • Publication number: 20220367053
    Abstract: Systems and methods can quantify the tumor microenvironment for diagnosis, prognosis and therapeutic response prediction by fusing different data types (e.g., morphological information from histology and molecular information from omics) using an algorithm that harnesses deep learning. The algorithm employs tensor fusion to provide end-to-end multimodal fusion to model the pairwise interactions of features across multiple modalities (e.g., histology and molecular features) and deep learning. The systems and methods improve upon traditional methods for quantifying the tumor microenvironment that rely on concatenation of extracted features.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 17, 2022
    Inventors: Faisal Mahmood, Richard Chen
  • Patent number: 11481391
    Abstract: A distributed database system maintains data for a logical table by storing, on a plurality of storage nodes, a collection of key-item pairs. The distributed database system receives a query of the logical table, and identifies one or more portions of a key specified by the query. Based on the one or more portions of the key, the distributed database causes at least one of a get, range query, or scan operation to be performed by one or more of the storage nodes. Results for the query are generated based on one or more items obtained by performance of the operation.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: October 25, 2022
    Assignee: Amazon Technologies, Inc.
    Inventors: Almero Gouws, Derek William Richard Chen-Becker, Akshat Vig, Haifeng He
  • Patent number: 11456058
    Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: September 27, 2022
    Assignee: Personalis, Inc.
    Inventors: Jason Harris, Mark R. Pratt, John West, Richard Chen, Ming Li
  • Publication number: 20220292285
    Abstract: One embodiment of the invention provides a method for video recognition. The method comprises receiving an input video comprising a sequence of video segments over a plurality of data modalities. The method further comprises, for a video segment of the sequence, selecting one or more data modalities based on data representing the video segment. Each data modality selected is optimal for video recognition of the video segment. The method further comprises, for each data modality selected, providing at least one data input representing the video segment over the data modality selected to a machine learning model corresponding to the data modality selected, and generating a first type of prediction representative of the video segment via the machine learning model. The method further comprises determining a second type of prediction representative of the entire input video by aggregating all first type of predictions generated.
    Type: Application
    Filed: March 11, 2021
    Publication date: September 15, 2022
    Inventors: Rameswar Panda, Richard Chen, Quanfu Fan, Rogerio Schmidt Feris
  • Publication number: 20220277810
    Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
    Type: Application
    Filed: May 17, 2022
    Publication date: September 1, 2022
    Inventors: Jason Harris, Mark R. Pratt, John West, Richard Chen, Ming Li
  • Publication number: 20220275446
    Abstract: This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions.
    Type: Application
    Filed: May 18, 2022
    Publication date: September 1, 2022
    Inventors: John West, Christian Haudenschild, Richard Chen
  • Publication number: 20220275445
    Abstract: This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions.
    Type: Application
    Filed: May 13, 2022
    Publication date: September 1, 2022
    Inventors: Gabor T. Bartha, Gemma Chandratillake, Richard Chen, Sarah Garcia, Hugo Yu Kor Lam, Shujun Luo, Mark R. Pratt, John West
  • Patent number: 11408033
    Abstract: This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: August 9, 2022
    Assignee: Personalis, Inc.
    Inventors: Gabor T. Bartha, Gemma Chandratillake, Richard Chen, Sarah Garcia, Hugo Yu Kor Lam, Shujun Luo, Mark R. Pratt, John West
  • Patent number: 11385948
    Abstract: A distributed database system maintains data for a database client by storing data on a plurality of storage nodes. Upon receiving a request from the database client in a first format, the database system translates the request to a second format and sends the translated request to a storage subsystem. The storage subsystem generates an exception if the translated request cannot be successfully completed. The distributed database system resends the translated request on behalf of the database client if the exception corresponds to a request that can be retried, and continues to resend the translated request until a first of an expiration of a predetermined time period or until the request completes successfully. The distributed database system sends a response to the database client based on the resent database request.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: July 12, 2022
    Assignee: Amazon Technologies, Inc.
    Inventors: Danielle Livneh, Almero Gouws, Derek William Richard Chen-Becker, Stefano Stefani, Akshat Vig, Zoe Wheeler, Lakshmi Narasimha Guptha Munuhur Rajagopal
  • Patent number: 11384394
    Abstract: This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: July 12, 2022
    Assignee: Personalis, Inc.
    Inventors: Gabor T. Bartha, Gemma Chandratillake, Richard Chen, Sarah Garcia, Hugo Yu Kor Lam, Shujun Luo, Mark R. Pratt, John West
  • Patent number: 11372651
    Abstract: A method for bootstrapping a variational algorithm for quantum computing includes performing, using a quantum processor, a first iteration of a variational algorithm on a first wavefunction to compute a first expectation value of a first quantum system corresponding to a solution of the first iteration, the first wavefunction corresponding to a first quantum state of the first quantum system, the first expectation value comprising an energy of the first quantum state. The embodiment includes generating, based on the solution of the first iteration a second wavefunction as output of the first iteration of the variational algorithm, the second wavefunction corresponding to a second quantum state of the first quantum system.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: June 28, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen Wood, Richard Chen, Marco Pistoia, Antonio Mezzacapo, Jay M. Gambetta
  • Publication number: 20220195520
    Abstract: This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions.
    Type: Application
    Filed: March 7, 2022
    Publication date: June 23, 2022
    Inventors: John West, Christian Haudenschild, Richard Chen
  • Patent number: 11365446
    Abstract: This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: June 21, 2022
    Assignee: Personalis, Inc.
    Inventors: Gabor T. Bartha, Gemma Chandratillake, Richard Chen, Sarah Garcia, Hugo Yu Kor Lam, Shujun Luo, Mark R. Pratt, John West
  • Publication number: 20220188381
    Abstract: Techniques regarding an iterative energy-scaled variational quantum eigensolver process are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a read-out component that determines a ground state energy value of a quantum Hamiltonian by employing a variational quantum eigensolver (VQE) algorithm, wherein VQE algorithm utilizes a symmetry that emerges at an energy scale of the quantum Hamiltonian.
    Type: Application
    Filed: March 3, 2022
    Publication date: June 16, 2022
    Inventors: Antonio Mezzacapo, Richard Chen, Marco Pistoia