Abstract: The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.

Abstract: A swiveling strap extension device and method of use is operable with an instrument strap. The extension device comprises a flat, elongated longitudinal member having an instrument end that attaches to an instrument. The instrument end has size-adjustable eyelets that fasten to the instrument at mount buttons. The swivel end has a terminus section and a body section. The terminus section attaches to a free end of the instrument strap. A swivel-coupling connects the terminus and body sections. The swivel coupling swivels up to 360°, allowing the terminus section to rotate correspondingly. The swivel-coupling is disposed at a fixed length from the instrument. The fixed length is defined as the distance from the eyelets to the terminus section of the swivel end. The fixed length enables the swivel-coupling to be disposed approximately in an open space that forms between the instrument and the back of an instrument operator.

Abstract: A transposable capo system for a stringed musical instrument includes at least one magnetic capo stud having a string slot adapted to receive a string on the instrument.

Abstract: A mobile station (101) for use in a wireless communication system includes a steerable antenna, means for obtaining location information relating to a current location of the mobile station and a steering controller for controlling a pointing direction of the steerable antenna using the location information and characterized in that the mobile station includes a memory holding a database of optimal pointing directions of the steerable antenna for given locations and the steering controller is operable to steer the antenna to the optimal pointing direction indicated in the database for the current location. Also described is a system and a method in which the mobile station operates.

Abstract: A transposable capo system for a stringed musical instrument includes at least one magnetic capo stud having a string slot adapted to receive a string on the instrument.

Abstract: An apparatus and method for synchronization between uncoordinated Time Division Duplex (TDD) communication networks includes a first step (300) of measuring an interference level on channels available to a base station. A next step (302) includes choosing the channel having the lowest interference level. A next step (304) includes determining that the interference is from a base station. A next step (306) includes calculating an interference profile over the frame cycle. A next step (308) includes establishing a peak interference level. A next step (310) includes aligning the base station frame timing in response to the peak interference level.

Abstract: A mobile communication system is described. The system has an infrastructure that includes base stations and has mobile stations, a mobile terminal and a mobile controller. Each mobile station is operable to communicate with one of the base stations. The mobile terminal is coupled to first and second mobile stations to provide a communication link to at least one of the base stations. The mobile controller sends instruction messages to the mobile stations regarding connectivity with the base stations. The mobile terminal, the mobile controller and the first and second mobile stations are carried on a moving object. The mobile controller makes decisions and issues instructions to the mobile stations relating to the base station by which they should each be served with to maintain a communication link between the mobile terminal and a serving base station via at least one of the mobile stations.

Abstract: There is disclosed, a mobile station, and a method for candidate cell evaluation in a fast moving environment. The method includes receiving a plurality of transmissions from a plurality of candidate cells, where each of the plurality of transmissions corresponds to one of the plurality candidate cells. The method further includes measuring signal strengths of the plurality of transmissions and determining change in the signal strengths of the plurality of transmissions. The method further includes calculating a weighting factor corresponding to the plurality of candidate cells based on the measured signal strengths, the change in the signal strength, and a Doppler and assigning priority levels to the plurality of candidate cells based on the calculated weighting factor.

Abstract: An apparatus and method for synchronization between uncoordinated Time Division Duplex (TDD) communication networks includes a first step (300) of measuring an interference level on channels available to a base station. A next step (302) includes choosing the channel having the lowest interference level. A next step (304) includes determining that the interference is from a base station. A next step (306) includes calculating an interference profile over the frame cycle. A next step (308) includes establishing a peak interference level. A next step (310) includes aligning the base station frame timing in response to the peak interference level.

Abstract: A mobile station (101) for use in a wireless communication system includes a steerable antenna, means for obtaining location information relating to a current location of the mobile station and a steering controller for controlling a pointing direction of the steerable antenna using the location information and characterised in that the mobile station includes a memory holding a database of optimal pointing directions of the steerable antenna for given locations and the steering controller is operable to steer the antenna to the optimal pointing direction indicated in the database for the current location. Also described is a system and a method in which the mobile station operates.

Abstract: A mobile communication system includes an infrastructure which includes a plurality of base stations, a plurality of mobile stations each of which is operable to communicate with a selected one of the base stations, a mobile terminal operably coupled to at least a first one of the mobile stations and a second one of the mobile stations to provide a communication link to at least one of the base stations, and a mobile controller which is operable to send instruction messages to the mobile stations regarding connectivity with the base stations. The mobile terminal, the mobile controller and the first and second mobile stations may be carried on a moving object such as a person or a vehicle, e.g. a train or aeroplane.

Abstract: A charge-splitting device and method include a plurality of charge cells coupled to receive a charge in response to being simultaneously clocked into a charge receiving state by an applied clock signal. The received charge is split into predetermined charge portions among the plurality of charge cells in proportions dependent upon the total number of cells, their relative capacitance and the magnitude and timing of the applied clock signal. The charge portions are again split and selectively summed to obtain highly accurate charge splitting ratios.