Patents by Inventor Richard Cortese

Richard Cortese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-unit pulsatile delivery system
    Patent number: 5017381
    Abstract: The present invention is directed to an active agent dispenser for use in a fluid-containing environment, which dispenser comprises a rigid housing, a plurality of movable active agent units filling a portion of the housing, a fluid-activated driving member for dispensing the active agent units filling the remainder of the housing, and an active agent unit outlet means. In the present invention, each active agent unit is comprised of an active agent dosage or filling contained within a fluid-impermeable cup-shaped member, the cup-shaped members being oriented within the housing with the base of the cup-shaped members facing the outlet means.
    Type: Grant
    Filed: May 2, 1990
    Date of Patent: May 21, 1991
    Assignee: Alza Corporation
    Inventors: Frederick Maruyama, Richard Cortese
  • Dispenser comprising hydrophilic osmopolymer
    Patent number: 5000957
    Abstract: A dispensing system is disclosed comprising a wall surrounding a lumen. The lumen comprises (1) a thermo responsive composition comprising a beneficial agent, (2) means for occupying space in the lumen for pushing the thermo responsive composition from the dispensing system, and (3) means for enhancing the amount of the beneficial agent dispensed from the system positioned between the thermo responsive composition and the means for occupying space.
    Type: Grant
    Filed: March 28, 1989
    Date of Patent: March 19, 1991
    Assignee: Alza Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Device comprising liner for protecting fluid sensitive medicament
    Patent number: 4996060
    Abstract: A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
    Type: Grant
    Filed: April 6, 1989
    Date of Patent: February 26, 1991
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Judy A. Magruder, Richard Cortese, John R. Peery, Jeremy C. Wright
  • Method for delivering dosage form for diltiazem
    Patent number: 4966769
    Abstract: A device is disclosed for delivering diltiazem at a controlled and substantially zero order rate over a prolonged period of time.
    Type: Grant
    Filed: May 11, 1989
    Date of Patent: October 30, 1990
    Assignee: ALZA Corporation
    Inventors: George V. Guittard, Patrick S. L. Wong, Felix Theeuwes, Richard Cortese
  • Method for delivering somatotropin to an animal
    Patent number: 4959218
    Abstract: A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
    Type: Grant
    Filed: December 28, 1988
    Date of Patent: September 25, 1990
    Assignee: Alza Corporation
    Inventors: James B. Eckenhoff, Judy A. Magruder, Richard Cortese, John R. Peery, Jeremy C. Wright
  • Dispenser comprising displaceable matrix with solid state properties
    Patent number: 4940465
    Abstract: A dispenser is enclosed for delivering a beneficial agent to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first means in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, a beneficial agent in the first means, and a second means in the dispenser for aiding in displacing the first means from the dispenser.
    Type: Grant
    Filed: November 7, 1988
    Date of Patent: July 10, 1990
    Inventors: Felix Theeuwes, Patrick S.-L. Wong, Richard Cortese, James B. Eckenhoff
  • Dispenser for delivering drug to livestock
    Patent number: 4927633
    Abstract: A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) heat responsive means containing a beneficial agent in the spece, (3) means for increasing the amount of beneficial agent delivered from the device in the space, (4) expandable means in the space, (5) an optional dense means in the space, and (6) means in the housing for delivering the beneficial agent from the dispensing device.
    Type: Grant
    Filed: June 24, 1987
    Date of Patent: May 22, 1990
    Assignee: Alza Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Dispenser with movable matrix comprising a plurality of tiny pills
    Patent number: 4915949
    Abstract: A dispenser is disclosed for delivering tiny pills to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, tiny pills in the first means, and a second means in the dispenser for aiding in displacing the first means for the dispenser.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: April 10, 1990
    Assignee: Alza Corporation
    Inventors: Patrick S.-L. Wong, Felix Theeuwes, Richard Cortese, James B. Eckenhoff
  • Juxtaposed laminated arrangement
    Patent number: 4892778
    Abstract: A dispenser is enclosed for delivering a beneficial agent to an enviroment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, a beneficial agent in the first means, and a second means in the dispenser for aiding in displacing the first means from the dispenser.
    Type: Grant
    Filed: May 27, 1987
    Date of Patent: January 9, 1990
    Assignee: ALZA Corporation
    Inventors: Felix Theeuwes, Patrick S. L. Wong, Richard Cortese, James B. Eckenhoff
  • Dosage form for delivering diltiazem
    Patent number: 4859470
    Abstract: A device is disclosed for delivering diltiazem at a controlled and substantially zero order rate over a prolonged period of time.
    Type: Grant
    Filed: June 2, 1988
    Date of Patent: August 22, 1989
    Assignee: Alza Corporation
    Inventors: George V. Guittard, Patrick S. L. Wong, Felix Theeuwes, Richard Cortese
  • Device comprising means for protecting and dispensing fluid sensitive medicament
    Patent number: 4855141
    Abstract: A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: August 8, 1989
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Judy A. Magruder, Richard Cortese, John R. Peery, Jeremy C. Wright
  • Dispensing system with means for increasing delivery of beneficial agent from the system
    Patent number: 4844984
    Abstract: A dispensing system is disclosed comprising a wall surrounding a lumen. The lumen comprises (1) a thermo responsive composition comprising a beneficial agent, (2) means for occupying space in the lumen for pushing the thermo responsive composition from the dispensing system, and (3) means for enhancing the amount of the beneficial agent dispensed from the system positioned between the thermo responsive composition and the means for occupying space.
    Type: Grant
    Filed: March 24, 1988
    Date of Patent: July 4, 1989
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Dispenser with movable matrix comprising a plurality of tiny pills
    Patent number: 4824675
    Abstract: A dispenser is disclosed for delivering tiny pills to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, tiny pills in the first means, and a second means in the dispenser for aiding in displacing the first means for the dispenser.
    Type: Grant
    Filed: July 13, 1987
    Date of Patent: April 25, 1989
    Assignee: ALZA Corporation
    Inventors: Patrick S. L. Wong, Felix Theeuwes, Richard Cortese, James B. Eckenhoff
  • Dispenser with internal arrangement of lamina means for dispensing beneficial agent
    Patent number: 4772474
    Abstract: A dispensing system is disclosed comprising a wall surrounding a lumen. The lumen comprises (1) a thermo responsive composition comprising a beneficial agent, (2) means for occupying space in the lumen for pushing the thermo responsive composition from the dispensing system, and (3) means for enhancing the amount of the beneficial agent dispensed from the system positioned between the thermo responsive composition and the means for occupying space.
    Type: Grant
    Filed: August 11, 1986
    Date of Patent: September 20, 1988
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Process for manufacturing a thermoplastic molding composition
    Patent number: 4731122
    Abstract: The invention concerns a process for producing a thermoplastic composition comprising a cellulose ester.
    Type: Grant
    Filed: March 30, 1987
    Date of Patent: March 15, 1988
    Assignee: ALZA Corporation
    Inventors: Richard Cortese, Jeremy C. Wright, James B. Eckenhoff, David L. Rivera
  • Composition for manufacturing wall of dispensing device
    Patent number: 4729793
    Abstract: A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) heat responsive means containing a beneficial agent in the space, (3) means for increasing the amount of beneficial agent delivered from the device in the space, (4) expandable means in the space, (5) an optional dense means in the space, and (6) means in the housing for delivering the beneficial agent from the dispensing device.
    Type: Grant
    Filed: September 2, 1986
    Date of Patent: March 8, 1988
    Assignee: Alza Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Dosage system and method of using same
    Patent number: 4717566
    Abstract: A dosage form is disclosed for delivering a beneficial agent. The dosage form comprises a wall that surrounds and defines an internal space, a composition comprising a beneficial agent, means in the space for aiding in delivering the compositions from the dosage form and, at least one passageway in the wall for delivering the composition from the dosage form.
    Type: Grant
    Filed: June 23, 1986
    Date of Patent: January 5, 1988
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Device for the controlled delivery of a beneficial agent
    Patent number: 4717718
    Abstract: A device for the controlled delivery of a beneficial agent is disclosed. The device comprises (a) a formulation layer and (b) a layer comprising means for pushing the formualtion layer from said device. The formulation layer comprises the beneficial agent avermectin or ivermectin.
    Type: Grant
    Filed: August 11, 1986
    Date of Patent: January 5, 1988
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Laminar arrangement for increasing delivery of beneficial agent from dispenser
    Patent number: 4717568
    Abstract: A laminated arrangement useful for manufacturing a deliver device for delivering a beneficial agent formulation is disclosed. The laminated arrangement comprise first lamina means comprising a beneficial agent formulation in laminar arrangement with a second lamina means exhibiting a lower passage to the beneficial agent then the first lamina means.
    Type: Grant
    Filed: August 11, 1986
    Date of Patent: January 5, 1988
    Assignee: Alza Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau
  • Self controlled release device for administering beneficial agent to recipient
    Patent number: 4692336
    Abstract: A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) a heat responsive composition containing a beneficial agent in the space, (3) an expandable member in the space, and (4) at least one passageway in the housing for delivering the beneficial agent from the dispensing device.
    Type: Grant
    Filed: August 7, 1985
    Date of Patent: September 8, 1987
    Assignee: ALZA Corporation
    Inventors: James B. Eckenhoff, Richard Cortese, Felix A. Landrau