Abstract: The present invention provides a method for monitoring adherence by a patient to a medication. The method comprises the steps of obtaining timing data in respect of each dose of a medication taken by a patient over a time interval, estimating the concentration of the medication in the patient's body over the time interval based on the dose timing data; determining the proportion of time over the time interval the concentration of the medication in the patient's body exceeds a target concentration; and calculating an adherence score for the patient based on the determined proportion of time the concentration of the medication in the patient's body exceeds the target concentration.

Abstract: A rotorcraft including a rotor hub, a pitch housing moveable relative to the rotor hub about at least a feather axis and a flap axis, the pitch housing defining an internal volume, a bearing pin, the inboard end portion of the bearing pin being fixedly connected to the rotor hub, wherein the bearing pin defines the feather axis, a spherical bearing connected to the inboard end portion of the pitch housing and defining the flap axis, wherein the bearing pin extends through the spherical bearing, a rotor blade connected to the outboard end portion of the pitch housing, and a sensor assembly positioned in the internal volume and operatively connected to both the pitch housing and the outboard end portion of the bearing pin.

Abstract: A system and method suitable for monitoring user technique of an inhaler device configured for delivery of a medicament is provided. The system may include a microphone adapted for sensing sound made during operation of the inhaler device and processing circuitry operable to process a data signal obtained from the microphone, wherein the data signal includes acoustic information sensed. The processing circuitry is adapted to determine inhalation and exhalation breath characteristics that occur during use, by analyzing the temporal and spectral components of the acoustic information sensed and processed to differentiate between an inhalation and an exhalation, based on both the temporal and spectral components. This information can be processed to determine user technique adherence to inhaler or respiratory device protocol. The analysis of temporal and spectral components can determine the impact of user technique errors on the quantity and the deposition of medicament delivered into the user's airways.

Abstract: A rotorcraft including a rotor hub, a pitch housing moveable relative to the rotor hub about at least a feather axis and a flap axis, the pitch housing defining an internal volume, a bearing pin, the inboard end portion of the bearing pin being fixedly connected to the rotor hub, wherein the bearing pin defines the feather axis, a spherical bearing connected to the inboard end portion of the pitch housing and defining the flap axis, wherein the bearing pin extends through the spherical bearing, a rotor blade connected to the outboard end portion of the pitch housing, and a sensor assembly positioned in the internal volume and operatively connected to both the pitch housing and the outboard end portion of the bearing pin.

Abstract: A vehicle tie-down cleat assembly can include (i) a tie-down cleat defining an upper portion and a lower portion, wherein the upper portion defines at least one aperture or member configured to receive a tying member, and wherein the tie-down cleat comprises a plastic housing and a metal insert disposed within the plastic housing, and (ii) a base assembly coupled to the lower portion of the tie-down cleat and configured to be removably coupled to a surface of a storage compartment of the vehicle, the base assembly comprising a base member, a hinge coupled to the lower portion of the tie-down cleat and the base member, the hinge being configured to allow the tie-down cleat to rotate with respect to the base assembly, and a locking system configured to lock/unlock the tie-down cleat assembly to a mounting plate mounted to a surface of a vehicle storage compartment.

Abstract: A system and method suitable for monitoring user technique of an inhaler device configured for delivery of a medicament is provided. The system may include a microphone adapted for sensing sound made during operation of the inhaler device and processing circuitry operable to process a data signal obtained from the microphone, wherein the data signal includes acoustic information sensed. The processing circuitry is adapted to determine inhalation and exhalation breath characteristics that occur during use, by analysing the temporal and spectral components of the acoustic information sensed and processed to differentiate between an inhalation and an exhalation, based on both the temporal and spectral components. This information can be processed to determine user technique adherence to inhaler or respiratory device protocol. The analysis of temporal and spectral components can determine the impact of user technique errors on the quantity and the deposition of medicament delivered into the user's airways.

Abstract: A thirteen sided collapsible container in which wet and dry food can be distributed from fabricated with one die cut and scored piece of a non permeable coated paperboard which contains fluids without warping or leaking. This invention is intended to be packaged with foods such as microwave popcorn to serve as a disposable container to consume edible product from. The invention may also be utilized as a container for food to be consumed from in instances where packing space is limited, such as a backpack for camping or hiking.