Abstract: A medication injection method where a medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.

Abstract: Methods for filling a prescription are provided. In some instances, a method for filling a prescription includes providing a housing and a locking cap. The locking cap is configured to be fixedly secured to the housing, a first member of the locking cap is configured to threadedly engage the housing, the locking cap is configured to be fixedly secured to the housing via a plurality of latching members of the first member of the locking cap, and the plurality of latching members are configured to encase a lip of the housing. The method for filling the prescription further includes filling, by an authorized user, the housing with a substance; receiving a unique identifier associated with an intended user; and coupling, by the authorized user, the housing and the locking cap.

Abstract: A substance dispensing apparatus comprises a housing for handheld use and a mouthpiece coupled to the housing. The housing comprises a biometric sensor and a cavity sized to receive a reservoir. The mouthpiece comprises a recess and a capacitive sensor array. The apparatus further comprises a pump coupled to the mouthpiece and couplable to the reservoir and comprises a processor in communication with the biometric sensor, capacitive sensor array, and pump. The processor is configured to cause the pump to automatically dispense a substance from the reservoir to a mouth of an intended user via the mouthpiece in response to determining that: a unique biometric attribute of the intended user is detected by the biometric sensor based on biometric data from the biometric sensor; and a unique dentition of the intended user is positioned within the recess of the mouthpiece based on dentition data from the capacitive sensor array.

Abstract: A removal device (121, 221) for removing and disposing of a pen needle (113, 213) connectable to a drug delivery device (111, 211) includes a body (123, 223) having a cavity (141, 241) for receiving the pen needle of the drug delivery device such that a patient end (116, 216) of a needle (115, 215) of the pen needle is covered by the body. An ejector (151, 251) is movably connected to the body (123, 223) for engaging the received pen needle (113, 213) and selectively ejecting the engaged pen needle from the body. The pen needle (113, 213) is securely retained within the removal device (121, 221) without exposing the needle (115, 215) of the pen needle until the pen needle (113, 213) can be properly disposed of, such as in a sharps container, thereby substantially preventing an accidental needle stick.

Abstract: Methods of securely dispensing a substance to an intended user are provided. In some instances, a method of securely dispensing a substance to an intended user includes moving a valve of a locking cap fixedly secured to a housing containing the substance to an open state that allows the substance to be dispensed from the housing to the intended user; determining that a unique biometric attribute of the intended user is detected; and dispensing the substance from the housing to the intended user in response to determining that the unique biometric attribute of the intended user is detected.

Abstract: An injection pen, comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during dose setting and dose correcting and engaged with the second mating feature during an injection.

Abstract: An injection method is provided for using an injection pen, the injection pen comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during the dose setting and the dose correcting and engaged with the second mating feature during the injection.

Abstract: A system including an adapter for sequential engagement with a cartridge containing a first substance and a vial containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member engageable with a portion of the cartridge. A plunger rod includes a protrusion and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.

Abstract: A medication injection method where a dose set knob of a medication injection pen is rotated with respect to the housing of the medication injection pen during dose setting and dose correcting, a driver is selectively engages with the dose set knob, the driver being rotatably fixed with respect to the housing during dose setting and dose correcting, the driver is moved axially with the dose set knob during the dose setting and the dose correcting, and the driver is rotated with the dose set knob during an injection.

Abstract: A removal device (121, 221) for removing and disposing of a pen needle (113, 213) connectable to a drug delivery device (111, 211) includes a body (123, 223) having a cavity (141, 241) for receiving the pen needle of the drug delivery device such that a patient end (116, 216) of a needle (115, 215) of the pen needle is covered by the body. An ejector (151, 251) is movably connected to the body (123, 223) for engaging the received pen needle (113, 213) and selectively ejecting the engaged pen needle from the body. The pen needle (113, 213) is securely retained within the removal device (121, 221) without exposing the needle (115, 215) of the pen needle until the pen needle (113, 213) can be properly disposed of, such as in a sharps container, thereby substantially preventing an accidental needle stick.

Abstract: A medication injection method where a dose set knob of a medication injection pen is rotated with respect to the housing of the medication injection pen during dose setting and dose correcting, a driver is selectively engages with the dose set knob, the driver being rotatably fixed with respect to the housing during dose setting and dose correcting, the driver is moved axially with the dose set knob during the dose setting and the dose correcting, and the driver is rotated with the dose set knob during an injection.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: An injection pen, comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during dose setting and dose correcting and engaged with the second mating feature during an injection.

Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separating a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space and a cooling tube. In some examples, the UV light source is configured to emit light with wavelengths with a desired intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: An injection pen, comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during the dose setting and the dose correcting and engaged with the second mating feature during the injection.

Abstract: A substance dispensing apparatus comprises a housing for handheld use and a mouthpiece coupled to the housing. The housing comprises a biometric sensor and a cavity sized to receive a reservoir. The mouthpiece comprises a recess and a capacitive sensor array. The apparatus further comprises a pump coupled to the mouthpiece and couplable to the reservoir and comprises a processor in communication with the biometric sensor, capacitive sensor array, and pump. The processor is configured to cause the pump to automatically dispense a substance from the reservoir to a mouth of an intended user via the mouthpiece in response to determining that: a unique biometric attribute of the intended user is detected by the biometric sensor based on biometric data from the biometric sensor; and a unique dentition of the intended user is positioned within the recess of the mouthpiece based on dentition data from the capacitive sensor array.

Abstract: Computerized oral prescription administration with refillable medication dispensing devices and associated systems and methods are provided. In one embodiment, a method of dispensing a substance to an intended user is provided. The method comprises receiving an input from a biometric sensor; determining, based on the received input, whether an intended user's unique biometric attribute is detected by the biometric sensor; receiving an input from an environmental sensor; determining, based on the received input, whether a mouthpiece is positioned within a user's mouth; receiving an input from a capacitive sensor array of the mouthpiece; determining, based on the received input, whether an intended user's unique dentition is positioned within a recess of the mouthpiece; and dispensing a substance from a reservoir to a mouth of the intended user in response to determining that the intended user's unique biometric attribute is detected by the biometric sensor.

Abstract: A device for delivering a fluid includes a housing defining an interior space and having a bottom surface configured for contacting a patient. The bottom surface defines a needle opening. The device also includes a reservoir disposed within the interior space of the housing for containing a fluid therein, a needle carrier disposed within the housing, and an injection needle supported by the needle carrier and defining a lumen. The lumen of the injection needle is configured to be placed in fluid communication with the reservoir. The injection needle is transitionable from an initial position in which the injection needle is disposed within the housing, to a use position in which the injection needle extends through the needle opening, and a substantially shielded position in which the injection needle is disposed within the housing and the lumen of the needle is blocked by a portion of the housing.

Abstract: A device for delivering a fluid includes a housing defining an interior space and having a bottom surface configured for contacting a patient. The bottom surface defines a needle opening. The device also includes a reservoir disposed within the interior space of the housing for containing a fluid therein, a needle carrier disposed within the housing, and an injection needle supported by the needle carrier and defining a lumen. The lumen of the injection needle is configured to be placed in fluid communication with the reservoir. The injection needle is transitionable from an initial position in which the injection needle is disposed within the housing, to a use position in which the injection needle extends through the needle opening, and a substantially shielded position in which the injection needle is disposed within the housing and the lumen of the needle is blocked by a portion of the housing.