Abstract: The poly(pro-drug) material includes one or more alternating therapeutic compounds and biodegradable hydrocarbyl groups. The therapeutic compounds and biodegradable hydrocarbyl groups are separated by cleavable linker compounds. The therapeutic compounds, such as estrogen, curcumin, and fingolimod, include a plurality of substitutable functional groups that provide reaction sites for complexing with the cleavable linkers and in turn one or more polymers, such that the poly(pro-drug) material ends up composed of the therapeutic compound itself. In aqueous media and at physiological temperature and pH, the poly(pro-drug) materials degrade to release the therapeutic compounds from the material with a zero-order release profile, Advantageously, the poly(pro-drug) materials release the therapeutic compounds on time scales of years. The poly(pro-drug) materials also exhibit reduced to allow for prolonged implantation within a patient.

Abstract: The poly(pro-drug) material includes one or more alternating therapeutic compounds and biodegradable hydrocarbyl groups. The therapeutic compounds and biodegradable hydrocarbyl groups are separated by cleavable linker compounds. The therapeutic compounds, such as estrogen, curcumin, and fingolimod, include a plurality of substitutable functional groups that provide reaction sites for complexing with the cleavable linkers and in turn one or more polymers, such that the poly(pro-drug) material ends up composed of the therapeutic compound itself. In aqueous media and at physiological temperature and pH, the poly(pro-drug) materials degrade to release the therapeutic compounds from the material with a zero-order release profile. Advantageously, the poly(pro-drug) materials release the therapeutic compounds on time scales of years. The poly(pro-drug) materials also exhibit reduced to allow for prolonged implantation within a patient.

Abstract: The poly(pro-drug) material includes one or more alternating therapeutic compounds and biodegradable hydrocarbyl groups. The therapeutic compounds and biodegradable hydrocarbyl groups are separated by cleavable linker compounds. The therapeutic compounds, such as estrogen, curcumin, and fingolimod, include a plurality of substitutable functional groups that provide reaction sites for complexing with the cleavable linkers and in turn one or more polymers, such that the poly(pro-drug) material ends up composed of the therapeutic compound itself In aqueous media and at physiological temperature and pH, the poly(pro-drug) materials degrade to release the therapeutic compounds from the material with a zero-order release profile. Advantageously, the poly(pro-drug) materials release the therapeutic compounds on time scales of years. The poly(pro-drug) materials also exhibit reduced to allow for prolonged implantation within a patient.

Abstract: Provided are infrared reflective films comprising a substrate and at least one infrared reflective layer comprising an aminium radical cation compound in a crystalline state and an organic polymer, wherein the infrared reflective layer has a reflectance peak in the infrared region from 1250 nm to 1700 nm. Such infrared films are stable in their optical properties against degradation by light and moisture. Also provided are solar control window films, security markings, and other optical articles comprising such infrared reflective films. Further provided are methods for making such infrared reflective films.

Abstract: Provided are infrared reflective films comprising a substrate and at least one infrared reflective layer comprising an aminium radical cation compound in a crystalline state and an organic polymer, wherein the infrared reflective layer has a reflectance peak in the infrared region from 1250 nm to 1700 nm. Such infrared films are stable in their optical properties against degradation by light and moisture. Also provided are solar control window films, security markings, and other optical articles comprising such infrared reflective films. Further provided are methods for making such infrared reflective films.

Abstract: A windmill installation (10) includes a windmill (12) supported on a tower (18) that includes three legs (20, 22, and 24). The connections of the legs (20, 22, and 24) to their respective bases (36, 37, and 38) are provided by compliance members (30, 32, and 34) that are compliant enough that the natural frequency of axial bending of the windmill installation is less than the frequency with which blades (14) of the windmill (12) pass behind the tower (18). Also, a windmill compliance assembly (28) provides the connection between the windmill (12) and the tower (18) and has enough compliance that the natural frequency of pivotal bending is also below that frequency. As a result, vibration at a resonant frequency of the structure is avoided during normal operation.