Patents by Inventor Richard D. Ashby

Richard D. Ashby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240018095
    Abstract: Composition and methods for killing microorganisms using antimicrobial epoxy polymers and epoxy polymer curing agents are described. Compositions containing at least one compound of formula I where R1 is a phenolic group (e.g., simple phenol, creosote, thymol, or carvacrol), and where R2 is a polyamine (e.g., ethylenediamine (EDA), diethylenetriamine (DETA), triethylenetetramine (TETA), tetraethylenepentamine (TEPA), hexamethylenediamine (HDA)); and optionally a carrier; the compositions may additionally contain at least one epoxy resin. Methods for killing microorganisms involving contacting the microorganisms with an effective microorganism killing amount of the above composition.
    Type: Application
    Filed: September 28, 2023
    Publication date: January 18, 2024
    Inventors: HELEN N. LEW, KUN HUANG, RICHARD D. ASHBY, XUETONG FAN
  • Publication number: 20210094905
    Abstract: Compositions containing at least one compound of formula I where R1 is a phenolic compound (e.g., simple phenol, creosote, thymol, or carvacrol), and where R2 is a polyamine (e.g., ethylenediamine (EDA), diethylenetriamine (DETA), triethylenetetramine (TETA), tetraethylenepentamine (TEPA), hexamethylenediamine (HDA)); and optionally a carrier; the compositions may additionally contain at least one epoxy resin. Methods for killing microorganisms involving contacting the microorganisms with an effective microorganism killing amount of the above composition. Compositions containing at least one compound produced by a method involving reacting phenolic-branched chain fatty acid methyl ester with at least one polyamine.
    Type: Application
    Filed: August 21, 2020
    Publication date: April 1, 2021
    Inventors: Kun Huang, Richard D. Ashby, Xuetong Fan, Helen N. Lew, Robert A. Moreau
  • Patent number: 10799590
    Abstract: A composition comprising a bitter tastant and at least one sophorolipid and optionally a carrier; wherein the composition is edible and wherein the bitter taste of said bitter tastant is reduced. A method of reducing bitter taste attributed to a bitter tastant in an edible composition, said method comprising adding to said edible composition an effective amount of at least one sophorolipid and optionally a carrier; such that any bitter taste induced by the bitter tastant is reduced.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 13, 2020
    Assignees: The United States of America, as represented by the Secretary of Agriculture, Monell Chemical Senses Center
    Inventors: Daniel Solaiman, Richard D Ashby, Mehmet Hakan Ozdener, Alexander Bachmanov
  • Publication number: 20190060461
    Abstract: A composition comprising a bitter tastant and at least one sophorolipid and optionally a carrier; wherein the composition is edible and wherein the bitter taste of said bitter tastant is reduced. A method of reducing bitter taste attributed to a bitter tastant in an edible composition, said method comprising adding to said edible composition an effective amount of at least one sophorolipid and optionally a carrier; such that any bitter taste induced by the bitter tastant is reduced.
    Type: Application
    Filed: October 30, 2018
    Publication date: February 28, 2019
    Inventors: Daniel Solaiman, Richard D. Ashby, Mehmet Hakan Ozdener, Alexander Bachmanov
  • Patent number: 10190144
    Abstract: Pseudomonas chlororaphis NRRL B-30761 produces monorhamnolipids with predominantly 3-hydroxydodecenoyl-3-hydroxydecanoate (C12:1-C10) or 3-hydroxydodecanoyl-3-hydroxydecanoate (C12-C10) as the lipid moiety under static growth conditions. The cloning and sequencing of three genes and proteins involved in the biosynthesis of monorhamnose-lipid (R1L) is described. Expression of two of these genes, i.e., rhlA and rhlB, together in P. chlororaphis NRRL B-30761 increases R1L production by at least 10-fold. Also the generation of a recombinant P. chlororaphis NRRL B-30761 capable of synthesizing dirhamnose-lipid (R2L) is described. Characterization of R1L and R2L produced by the recombinant P. chlororaphis NRRL B-30761 is also described.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: January 29, 2019
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Daniel Solaiman, Richard D. Ashby, Jonathan A. Zerkowski, Nereus W. Gunther
  • Patent number: 10155043
    Abstract: A composition comprising a bitter tastant and at least one sophorolipid and optionally a carrier; wherein the composition is edible and wherein the bitter taste of said bitter tastant is reduced. A method of reducing bitter taste attributed to a bitter tastant in an edible composition, said method comprising adding to said edible composition an effective amount of at least one sophorolipid and optionally a carrier; such that any bitter taste induced by the bitter tastant is reduced.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: December 18, 2018
    Assignees: The United States of America, as Represented by the Secretary of Agriculture, Monell Chemical Senses Center
    Inventors: Daniel Solaiman, Richard D. Ashby, Mehmet Hakan Ozdener, Alexander Bachmanov
  • Publication number: 20170189533
    Abstract: A composition comprising a bitter tastant and at least one sophorolipid and optionally a carrier; wherein the composition is edible and wherein the bitter taste of said bitter tastant is reduced. A method of reducing bitter taste attributed to a bitter tastant in an edible composition, said method comprising adding to said edible composition an effective amount of at least one sophorolipid and optionally a carrier; such that any bitter taste induced by the bitter tastant is reduced.
    Type: Application
    Filed: December 22, 2016
    Publication date: July 6, 2017
    Inventors: Daniel Solaiman, Richard D. Ashby, Mehmet Hakan Ozdener, Alexander Bachmanov
  • Patent number: 9388444
    Abstract: The isolation and characterization of a glucosyltransferase gene from Candida bombicola is disclosed. Use of the glucosyltransferase enzyme for the production of glucosylated sterol and hydroxyl-fatty acid substrates is also disclosed. This enzyme has broad-specificity and is useful for the production of sophorolipids both in-vivo and in-vitro.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: July 12, 2016
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Daniel K Solaiman, Richard D Ashby, Jonathan A. Zerkowski, Robert A Moreau, Yanhong Liu
  • Publication number: 20160102330
    Abstract: Pseudomonas chlororaphis NRRL B-30761 produces monorhamnolipids with predominantly 3-hydroxydodecenoyl-3-hydroxydecanoate (C12:1-C10) or 3-hydroxydodecanoyl-3-hydroxydecanoate (C12-C10) as the lipid moiety under static growth conditions. The cloning and sequencing of three genes and proteins involved in the biosynthesis of monorhamnose-lipid (R1L) is described. Expression of two of these genes, i.e., rhlA and rhlB, together in P. chlororaphis NRRL B-30761 increases R1L production by at least 10-fold. Also the generation of a recombinant P. chlororaphis NRRL B-30761 capable of synthesizing dirhamnose-lipid (R2L) is described. Characterization of R1L and R2L produced by the recombinant P. chlororaphis NRRL B-30761 is also described.
    Type: Application
    Filed: June 3, 2014
    Publication date: April 14, 2016
    Inventors: Daniel Solaiman, Richard D. ASHBY, Jonathan A. ZERKOWSKI, Nereus W. GUNTHER
  • Publication number: 20150267236
    Abstract: The isolation and characterization of a glucosyltransferase gene from Candida bombicola is disclosed. Use of the glucosyltransferase enzyme for the production of glucosylated sterol and hydroxyl-fatty acid substrates is also disclosed. This enzyme has broad-specificity and is useful for the production of sophorolipids both in-vivo and in-vitro.
    Type: Application
    Filed: April 24, 2015
    Publication date: September 24, 2015
    Inventors: Daniel K Solaiman, Richard D Ashby, Jonathan A. Zerkowski, Robert A Moreau, Yanhong Liu
  • Patent number: 8980593
    Abstract: This invention relates to the production of short-chain polyhydroxyalkanoate biopolymers which include C3 to C5 3-hydroxyacyl monomers. The process includes culturing a native microorganism capable of synthesizing polyhydroxyalkanoate biopolymers using as a carbon source an amount of glycerol, levulinic acid and mixtures thereof that drives the microbial synthesis of polyhydroxyalkanoate biopolymers.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: March 17, 2015
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Richard D Ashby, Daniel K. Y. Solaiman, Gary D Strahan
  • Patent number: 7718782
    Abstract: A sophorolid produced by a method involving reacting a compound of formula I with a compound of formula II wherein R1 and R2 are H, C1-C18 alkyl, C3-C18 alkenyl, C3-C10 cycloalkyl, phenyl, or C1 through C18 acyl or alkoxycarbonyl, R1 and R2 are not both acyl, R3 is H, CH3, CH2-phenyl, CH2—C6H4—OH, CH2CO2H, CH2CH2CO2H, CH(CH3)2, CH2CH(CH3)2, CH(CH3)CH2CH3, CH2OH, CH(CH3)OH, CH2CH2CH2CH2NH2, CH2CH2CONH2, CH2CONH2, CH2—C3N2H3(histidine), CH2CH2CH2NHC(NH)NH2, CH2CH2SCH3, R2 and R3 may be joined in a ring, R4 is H, C1-C18 alkyl, C3-C18 alkenyl, C3-C10 cycloalkyl, or phenyl, n is 0-6, R5 and R6 are H, C1-C18 alkyl, C3-C18 alkenyl, C3-C10 cycloalkyl, or phenyl, and X is C1-C18 alkyl or C1-C18 alkenyl; optionally followed by acidolytic (treating with an acid) or hydrogenolytic deprotection (treating with a hydrogenolysis catalyst) which removes one of the groups R1 or R2 and replaces it with hydrogen.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: May 18, 2010
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Jonathan Zerkowski, Daniel Solaiman, Richard D. Ashby, Thomas A. Foglia
  • Patent number: 4166290
    Abstract: A computer monitoring system connects into the channel, serving as a link between a CPU and peripheral devices. Channel signals are extracted in a channel interface module, altered to be compatible with the logic in a data collection module and sent to a data collection module along with event codes generated within the channel interface module to indicate certain sequences and/or combinations of signals occurring on the channel. The data collection module is programmable to select those peripheral devices it wants to monitor and the type of information to be collected.
    Type: Grant
    Filed: May 10, 1978
    Date of Patent: August 28, 1979
    Assignee: Tesdata Systems Corporation
    Inventors: Eugene L. Furtman, Charles B. Ross, Richard D. Ashby, Steven D. Berliner
  • Patent number: RE31407
    Abstract: A computer monitoring system connects into the channel, serving as a link between a CPU and peripheral devices. Channel signals are extracted in a channel interface module, altered to be compatible with the logic in a data collection module and sent to a data collection module along with event codes generated within the channel interface module to indicate certain sequences and/or combinations of signals occurring on the channel. The data collection module is programmable to select those peripheral devices it wants to monitor and the type of information to be collected.
    Type: Grant
    Filed: August 13, 1980
    Date of Patent: October 4, 1983
    Assignee: Tesdata Systems Corporation
    Inventors: Eugene L. Furtman, Charles B. Ross, Richard D. Ashby, Steven D. Berliner