Patents by Inventor Richard D. Beger

Richard D. Beger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150065853
    Abstract: A system and method for preprocessing magnetic resonance spectroscopy (MRS) data of brain tissue for pattern-based diagnostics is disclosed. The MRS preprocessing system includes an MRS preprocessing module that executes an operation that normalizes MRS spectrum data, recalibrates and scales the normalized MRS spectrum data, and then renormalizes the scaled MRS spectrum data. The resulting preprocessed MRS data is used to assist in identifying abnormalities in tissues shown in MRS scans.
    Type: Application
    Filed: September 5, 2014
    Publication date: March 5, 2015
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Jon G. Wilkes, Dan A. Buzatu, Pierre Alusta, Bruce Pearce, Ryan M. Kretzer, Inessa IM, Richard D. Beger
  • Patent number: 8880354
    Abstract: A system and method for preprocessing magnetic resonance spectroscopy (MRS) data of brain tissue for pattern-based diagnostics is disclosed. The MRS preprocessing system includes an MRS preprocessing module that executes an operation that normalizes MRS spectrum data, recalibrates and scales the normalized MRS spectrum data, and then renormalizes the scaled MRS spectrum data. The resulting preprocessed MRS data is used to assist in identifying abnormalities in tissues shown in MRS scans.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: November 4, 2014
    Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Jon G. Wilkes, Dan A. Buzatu, Pierre Alusta, Bruce Pearce, Ryan M. Kretzer, Inessa Im, Richard D. Beger
  • Publication number: 20130131992
    Abstract: A system and method for preprocessing magnetic resonance spectroscopy (MRS) data of brain tissue for pattern-based diagnostics is disclosed. The MRS preprocessing system includes an MRS preprocessing module that executes an operation that normalizes MRS spectrum data, recalibrates and scales the normalized MRS spectrum data, and then renormalizes the scaled MRS spectrum data. The resulting preprocessed MRS data is used to assist in identifying abnormalities in tissues shown in MRS scans.
    Type: Application
    Filed: November 12, 2010
    Publication date: May 23, 2013
    Applicant: The Government USA as Represented by the Secretary Dept. of Health and Human Services
    Inventors: Jon G. Wilkes, Dan A. Buzatu, Pierre Alusta, Bruce Pearce, Ryan M. Kretzer, Inessa Im, Richard D. Beger
  • Patent number: 7996156
    Abstract: Structure-activity methods based on molecular descriptors that are a combination of structural information about the through-space and through-bond relationships between components of a molecule's structure and spectral data attributable to those components are disclosed. In some embodiments, a molecule is described by multiple sets of such descriptors to account for flexibility in the structure of the molecule. In a particularly disclosed embodiment, predicted 13C—13C COSY data and 13C—13C distance data are used as descriptors. Models of molecular properties may be established using the disclosed spectral data-activity methods and used to predict the properties of molecules.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: August 9, 2011
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Richard D. Beger, Jon G. Wilkes
  • Publication number: 20030229456
    Abstract: Structure-activity methods based on molecular descriptors that are a combination of structural information about the through-space and through-bond relationships between components of a molecule's structure and spectral data attributable to those components are disclosed. In some embodiments, a molecule is described by multiple sets of such descriptors to account for flexibility in the structure of the molecule. In a particularly disclosed embodiment, predicted 13C—13C COSY data and 13C—13C distance data are used as descriptors. Models of molecular properties may be established using the disclosed spectral data-activity methods and used to predict the properties of molecules.
    Type: Application
    Filed: March 7, 2003
    Publication date: December 11, 2003
    Applicant: The Gov. of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
    Inventors: Richard D. Beger, Jon G. Wilkes