Patents by Inventor Richard D. G. Woolfenden

Richard D. G. Woolfenden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of pleuromutilin derivatives against oxidation by sodium hypochlorite in aqueous solution
    Patent number: 4422945
    Abstract: A composition and method which provides a compound of the formula I: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5 andeach of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms.Also provided is a hypochlorite scavenger in solution with the formula I compound which stabilizes the compound against oxidation by sodium hypochlorite.A preferred solution contains the compound of formula I wherein R.sub.1 is vinyl, R.sub.2 and R.sub.3 are ethyl as a salt of hydrogen fumarate i.e. tiamulin hydrogen fumarate. The solution is added to drinking water which is fed to farm animals as treatment for mycoplasma infection.
    Type: Grant
    Filed: September 27, 1982
    Date of Patent: December 27, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frank Ridgway, Richard D. G. Woolfenden
  • Stabilization of pleuromutilin derivatives against oxidation by sodium hypochlorite in aqueous solution
    Patent number: 4390558
    Abstract: A composition and method which provides a compound of the formula I: ##STR1## wherein either R.sub.1 is ethyl or vinyl. n is an integer from 2 to 5 and each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms.Also provided is a hypochlorite scavenger in solution with the formula I compound which stabilizes the compound against oxidation by sodium hypochlorite.A preferred solution contains the compound of formula I wherein R.sub.1 is vinyl, R.sub.2 and R.sub.3 are ethyl as a salt of hydrogen fumarate i.e. tiamulin hydrogen fumarate. The solution is added to drinking water which is fed to farm animals as treatment for mycoplasma infection.
    Type: Grant
    Filed: March 6, 1981
    Date of Patent: June 28, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frank Ridgway, Richard D. G. Woolfenden