Abstract: A system for diagnosing vestibular otolith function can comprise an ultrasonic generator that is configured to direct ultrasonic waves towards vestibular organs with a patient's ear. The system can also comprise a response capture device that is configured to capture patient response to the ultrasonic waves.

Abstract: An apparatus for examining membrane-bound proteins in a cell can include a chamber with an insulating partition dividing the chamber into an upper well and a lower well, and a pore penetrating the insulating partition. The pore can have a size and shape so as to snugly hold a cell in place therein. The apparatus can further include circuitry for delivering a radio frequency signal to the cell. A belt electrode for delivering electrical signals to the cell can be located within the insulation partition and substantially encircling the pore. A measuring circuit for measuring cell membrane impedance to the radio frequency signal is also provided, and changes in the impedance can signal a change in state of a protein in the cell membrane.

Abstract: An apparatus for examining membrane-bound proteins in a cell can include a chamber with an insulating partition dividing the chamber into an upper well and a lower well, and a pore penetrating the insulating partition. The pore can have a size and shape so as to snugly hold a cell in place therein. The apparatus can further include circuitry for delivering a radio frequency signal to the cell. A belt electrode for delivering electrical signals to the cell can be located within the insulation partition and substantially encircling the pore. A measuring circuit for measuring cell membrane impedance to the radio frequency signal is also provided, and changes in the impedance can signal a change in state of a protein in the cell membrane.

Abstract: A method of measuring the electrical properties of a microparticle is provided, which can include multiple steps. Steps can include situating the microparticle within an array of electrodes submerged in a conductive medium so that the microparticle and electrodes are in electrical communication when the electrodes are energized, and delivering an electrical signal into the medium from one electrode to an immediately adjacent electrode. High frequency signals can be used to penetrate the microparticle boundary and characterize the same, and low frequency signals can be used to characterize the shape and orientation of the microparticle. Characterization can be carried out by measuring the impedance affecting the current using at least one of a remaining electrode in the array.

Abstract: A method of measuring the electrical properties of a microparticle is provided, which can include multiple steps. Steps can include situating the microparticle within an array of electrodes submerged in a conductive medium so that the microparticle and electrodes are in electrical communication when the electrodes are energized, and delivering an electrical signal into the medium from one electrode to an immediately adjacent electrode. High frequency signals can be used to penetrate the microparticle boundary and characterize the same, and low frequency signals can be used to characterize the shape and orientation of the microparticle. Characterization can be carried out by measuring the impedance affecting the current using at least one of a remaining electrode in the array.

Abstract: A micro-electric detector provides conductivity or impedance based measurements of a test sample placed in a microchannel of a micro-analysis system. The detector includes a pair of electrodes disposed on opposing sidewalls of the microchannel to create a detection zone in the microchannel between and adjacent to the electrodes. A variety of test samples can be monitored by the detector, such as particulate-containing fluids and biological materials including living cells and subcellular structures. The detector can be integrated on-chip using micromachining techniques with a variety of micro-analysis systems.