Abstract: Hydropyridine analogs, dihydropyridine analogs, trihydropyridine analogs, hydropurine analogs, dihydropurine analogs, trihydropurine analogs, N,N,N,'-trimethyl- N'-(2-hydroxy-3-methyl-1,3-propanediamone analogs, 1-methyl-3-[N-(4-iodophenyl)- carbamoyl]-1,4-dihydropyridine analogs, that are lipid-soluble with the specific electron charge density and therefore useful for the administration of several compounds that need to penetrate the blood-brain capillary barrier. Once inside the brain these compounds undergo NAD-NADH reduction thereby providing for a brain serum retention. These compounds having been modified herein to deliver various compounds, some of which are those that are progressively absent during the course of a disease called Alzheimer's Disease.

Abstract: Hydroypyridine analogs, Dihydropyridine analogs, Trihydropyridine analogs, Hydropurine analogs, Dihydropurine analogs, Trihydropurine analogs, N,N,N,'-trimethyl-N'-(2-hydroxy-3-methyl-1,3-propanediamine analogs, 1-methyl-3-[N-(4-iodophenyl)-carbamoyl]-1,4-dihydropyridine analogs, that are lipid-soluble with the specific electron charge density and therefore useful for the administration of several compounds that need to penetrate the blood-Brain capilliary barrier. Once inside the brain these compounds under go NAD-NADH reduction thereby providing for a brain serum retention. These compounds having been modified herein to deliver various compounds, some of which are those that are progressively absent during the course of a disease called Alzheimer's Disease.

Abstract: A rocker arm adapter for use in the timing mechanism of an internal combustion engine is disclosed. The adapter is a method for altering the cam profile of the exhaust valve of the engine with respect to the intake valve. It includes a fluidic delay device mounted in either the first end or the second end of the rocker arm. The delay device includes a piston which is allowed to move various distances in a cavity formed in the rocker arm, the distance being directly related to the speed of movement of a push rod member. As the speed of the engine, and the speed of movement of the push rod, increases, the piston will be allowed to move a greater distance into the cavity so that the delay in actuation of the rocker arm by the push rod is increased.