Patents by Inventor Richard Dana Kopke

Richard Dana Kopke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating acute acoustic trauma
    Patent number: 10555915
    Abstract: The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition 2,4-disulfonyl ?-phenyl tertiary butyl nitrone and N-acetylcysteine (NAC). Preferably, the compositions for treating AAT will be administered orally. However, other methods which deliver the compositions for treating AAT systemically to the body should work equally well.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: February 11, 2020
    Assignees: Hough Ear Institute, Oklahoma Medical Research Foundation
    Inventors: Richard Dana Kopke, Robert A. Floyd
  • Methods for treating acute acoustic trauma
    Patent number: 8420595
    Abstract: The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: April 16, 2013
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Richard Dana Kopke, Robert A. Floyd
  • METHODS FOR TREATING ACUTE ACOUSTIC TRAUMA
    Publication number: 20120172435
    Abstract: The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition 2,4-disulfonyl ?-phenyl tertiary butyl nitrone and N-acetylcysteine (NAC). Preferably, the compositions for treating AAT will be administered orally. However, other methods which deliver the compositions for treating AAT systemically to the body should work equally well.
    Type: Application
    Filed: August 24, 2010
    Publication date: July 5, 2012
    Inventors: Richard Dana Kopke, Robert A. Floyd
  • METHODS FOR TREATING ACUTE ACOUSTIC TRAUMA
    Publication number: 20100022458
    Abstract: The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally.
    Type: Application
    Filed: July 25, 2007
    Publication date: January 28, 2010
    Inventors: Richard Dana Kopke, Robert A. Floyd