Abstract: A load sensing assembly for a spinal implant is disclosed. The load sensing assembly may include: a set screw having a drive interface, a lower cavity for receiving a cover, the cover including a protrusion that may engage with an anchoring member. The load sensing assembly may further include an antenna, and at least one sensor having an integrated circuit in communication with the antenna. In some embodiments, the integrated circuit is positioned within a sealed cavity of the set screw. In some embodiments, the antenna comprises a ferrite core and a plurality of windings that are oriented laterally with respect to a longitudinal axis of the set screw. In some embodiments, the sealed cavity of the set screw is hermitically sealed, and the antenna may be mechanically isolated by a bellows or cylindrical can structure.

Abstract: One aspect of the invention provides a component 112, 165 for a fluid dispenser 110 which defines a dosing chamber 120 for a piston member 114 to stroke in and has an end 160 adapted for engaging a fluid outlet 152 of the fluid dispenser or a seal 154 which overlies the fluid outlet 152 to selectively close and open the fluid outlet 152 or seal 154. Other aspects are disclosed herein.

Abstract: One aspect of the invention provides a component 112, 165 for a fluid dispenser 110 which defines a dosing chamber 120 for a piston member 114 to stroke in and has an end 160 adapted for engaging a fluid outlet 152 of the fluid dispenser or a seal 154 which overlies the fluid outlet 152 to selectively close and open the fluid outlet 152 or seal 154. Other aspects are disclosed herein.

Abstract: One aspect of the invention provides a component for a fluid dispenser which defines a dosing chamber for a piston member to stroke in and has an end adapted for engaging a fluid outlet of the fluid dispenser or a seal which overlies the fluid outlet to selectively close and open the fluid outlet or seal. Other aspects are disclosed herein.

Abstract: A fluid dispenser that includes a dosing chamber, a piston member, a fluid outlet through which fluid will be dispensed, a fluid conduit configured to convey fluid from the dosing chamber towards the fluid outlet, and a seal for sealing the fluid outlet is described.

Abstract: An inhaler for delivering medicament by inhalation, comprising: a canister which comprises a body which defines a chamber containing medicament and a valve stem which extends from the body and from which medicament is in use delivered on actuation of the canister; and an actuator comprising a main body comprising a housing receiving the canister and actuating mechanism for actuating the canister, wherein the actuating mechanism comprises a loading member which engages or is comprised in the canister, and at least one actuating member which is depressible by a user to drive the loading member in an actuating direction from a first, rest position to a second, actuated position in which the canister is actuated to deliver medicament, wherein the at least one actuating member is a flexible element which has a first, flexed configuration when the loading member is in the first, rest position and, on depression, is extended in the actuating direction, such as to drive the loading member in the actuating direction f

Abstract: An actuator for an inhaler for delivering medicament by inhalation, comprising: a housing for receiving a canister comprising a body which defines a chamber containing medicament and a valve stem which extends from the body; and a priming mechanism for priming the actuator such as to be actuatable by a user, wherein the priming mechanism comprises a support member which includes a nozzle block for receiving the valve stem of the canister and which is movable relative to the housing between a first, inoperative position in which the canister is inactuatable and a second, primed position in which the canister is actuatable.

Abstract: An inhaler for delivering medicament by inhalation comprises a canister which comprises a body which includes a base and a head and defines a chamber containing medicament, and a valve stem which extends from the body and from which medicament is in use delivered on actuation of the canister. The inhaler also comprises an actuator comprising a main body comprising a housing receiving the canister, and an actuation mechanism for actuating the canister. The actuation mechanism comprises a loading member which is fitted to or comprised in the canister and includes a loading section which is located at a distance spaced from the base of the body of the canister and, in use, acted upon to drive the loading member in an actuating direction from a first, rest position to a second, actuated position in which the canister is actuated to deliver medicament.