Patents by Inventor Richard E. Andrews
Richard E. Andrews has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11975274Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).Type: GrantFiled: September 15, 2022Date of Patent: May 7, 2024Assignee: Velico Medical, Inc.Inventors: Qiyong Peter Liu, Herman E. Snyder, Kyle D. Erickson, Evan P. Ordway, William J. Merritt, Richard Meehan, Robert R. Andrews, Clair Strohl, Jihae Sohn, Mark A. Popovsky, Lisa A. Buckley
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Publication number: 20240109000Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).Type: ApplicationFiled: September 15, 2022Publication date: April 4, 2024Applicant: Velico Medical, Inc.Inventors: Qiyong Peter Liu, Herman E. Snyder, Kyle D. Erickson, Evan P. Ordway, William J. Merritt, Richard Meehan, Robert R. Andrews, Clair Strohl, Jihae Sohn
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Patent number: 11939564Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: GrantFiled: December 19, 2022Date of Patent: March 26, 2024Assignee: DEKA Products Limited PartnershipInventors: Michael C. Tilley, Richard E. Andrews, Dane C. Fawkes
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Publication number: 20240091666Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).Type: ApplicationFiled: January 17, 2023Publication date: March 21, 2024Applicant: Velico Medical, Inc.Inventors: Richard Meehan, Robert R. Andrews, Herman E. Snyder, William J. Merritt, Evan P. Ordway, Clair Strohl, Qiyong Peter Liu, Jihae Sohn
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Patent number: 11713442Abstract: Manufacturing system and method for creating multiple tissue constructs from cells. System can include a thaw subsystem (if the cells are provided in a frozen state), an expansion subsystem, a concentration subsystem, and a tissue maturation subsystem. Each of these subsystems is modular and can be reconfigured, and the process can be repeated depending on the specific tissue process being implemented. Multiple tissue types can be combined in multiple bioreactors. The activities of multiple bioreactors can be coordinated and controlled in an automated manner by a supervisor controller. The supervisor controller can receive user input at the start of the process, and can manage the process henceforth, alerting the user if user actions are required.Type: GrantFiled: June 17, 2020Date of Patent: August 1, 2023Assignee: DEKA PRODUCTS LIMITED PARTNERSHIPInventors: Richard E. Andrews, Stephanie M. Miskell, Zachary T. Kops, Justin M. Ferrentino, Michael C. Tilley, Andrew K. Capulli, Keira L McGrath, Stuart A. Jacobson
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Publication number: 20230193183Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: ApplicationFiled: December 19, 2022Publication date: June 22, 2023Inventors: Michael C. Tilley, Richard E. Andrews, Dane C. Fawkes
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Publication number: 20230105287Abstract: A system and method to enable treatment through cell therapy. The system can enable cell injection such as, for example, injecting beta cells/islets, cartilage cells, fat cells, and others. The system and method ensure that the delivery rate and delivered volume of the material pumped through a tube and into the injection needle is consistent over the course of the start-operation-stop process from run to run. The system and method can automatically stop delivery and alarm if an occlusion is detected during delivery.Type: ApplicationFiled: October 6, 2022Publication date: April 6, 2023Inventors: Hans E. JOHNSON, Andrew G. REMEC, David D. B. CANNAN, Keith D. VIOLETTE, Matthew A. NORRIS, Timothy D. MOREAU, Travis G. BIBEAU, Margaret B. BRADLEY, Stuart A. JACOBSON, Robert G. GLOEB-MCDONALD, Scott R. BOWDEN, Richard E. ANDREWS, Dominic P. LOPRIORE, Alden S. NAEEM, Trevor M. NARO, David A. SIMM
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Patent number: 11530380Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: GrantFiled: January 4, 2021Date of Patent: December 20, 2022Assignee: DEKA Products Limited PartnershipInventors: Michael C. Tilley, Richard E. Andrews, Dane C. Fawkes
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Publication number: 20220333056Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: ApplicationFiled: April 8, 2022Publication date: October 20, 2022Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR., Richard E. Andrews, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20220228097Abstract: A configurable system for repeatably performing processes related to tissue growth in a controlled environment, possibly part of an industrial production line. The system can accommodate various sizes and shapes of culture vessels, and can maintain the cells at a desired temperature in the culture vessels, thus enabling a plug and play system that can produce consistent and repeatable results. The system includes gas management, fluid management, and control of multiple processes simultaneously, and can be automatically operably coupled with a variety of supporting technologies that can enable tissue-related processes. The system can communicate with supporting technologies upstream and downstream on a manufacturing line, enabling fully automated process control, centralized data historization, and centralized control.Type: ApplicationFiled: January 20, 2022Publication date: July 21, 2022Inventors: Matthew WHITE, Stephanie M. MISKELL, Justin M. FERRENTINO, Richard E. ANDREWS, Stuart A. JACOBSON, Zachary KOPS
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Publication number: 20210340486Abstract: System and method for providing biocompatible, nutrient filled media to the Human Cells, Tissues, and cellular and tissue-based Products (HCT/P) while removing wastes. The present teachings provide for sensing the characteristics of the media, and modifying the characteristics when necessary. The present teachings can also provide components that can provide fluid pumping integrated with fluid gas exchange, and sensing of fluid characteristics at consistent times during the fluid flow cycle. System and method control multiple bioreactors from a centralized media reservoir, while fluidically isolating the bioreactors from cross-contamination.Type: ApplicationFiled: April 28, 2021Publication date: November 4, 2021Inventors: Richard E. Andrews, Dave D.B. Cannan, Alekhya Akkapeddi, Andrew G. Remec, Bryan A. Finseth, Kevin Kim
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Publication number: 20210147782Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: ApplicationFiled: January 4, 2021Publication date: May 20, 2021Inventors: Michael C. Tilley, Richard E. Andrews, Dane C. Fawkes
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Patent number: 10894942Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: GrantFiled: January 24, 2020Date of Patent: January 19, 2021Assignee: DEKA Products Limited PartnershipInventors: Michael C. Tilley, Jr., Richard E. Andrews, Dane C. Fawkes
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Publication number: 20200392450Abstract: Manufacturing system and method for creating multiple tissue constructs from cells. System can include a thaw subsystem (if the cells are provided in a frozen state), an expansion subsystem, a concentration subsystem, and a tissue maturation subsystem. Each of these subsystems is modular and can be reconfigured, and the process can be repeated depending on the specific tissue process being implemented. Multiple tissue types can be combined in multiple bioreactors. The activities of multiple bioreactors can be coordinated and controlled in an automated manner by a supervisor controller. The supervisor controller can receive user input at the start of the process, and can manage the process henceforth, alerting the user if user actions are required.Type: ApplicationFiled: June 17, 2020Publication date: December 17, 2020Inventors: Richard E. Andrews, Stephanie M. Miskell, Zachary T. Kops, Justin M. Ferrentino, Michael C. Tilley, Andrew K. Capulli, Keira L McGrath, Stuart A. Jacobson
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Publication number: 20200157486Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: ApplicationFiled: January 24, 2020Publication date: May 21, 2020Inventors: Michael C. Tilley, JR., Richard E. Andrews, Dane C. Fawkes
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Patent number: 10570362Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.Type: GrantFiled: August 30, 2018Date of Patent: February 25, 2020Assignee: DEKA Products Limited PartnershipInventors: Michael C. Tilley, Richard E. Andrews, Dane C. Fawkes
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Patent number: 6796381Abstract: A well pressure control assembly includes an annular pressure containment structure useful for manipulating pipe during drilling and other well operations performed with annular pressure at the wellhead. The annular pressure containment structure includes a sealing structure involving a sealing wall and a fluid port extending through the sealing wall through with a hydrodynamic bearing fluid is injectable adjacent pipe received in the annular pressure containment structure.Type: GrantFiled: June 25, 2002Date of Patent: September 28, 2004Assignee: Ormexla USA, Inc.Inventors: Maynard F. Ayler, Richard E. Andrews
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Publication number: 20030089506Abstract: A well pressure control assembly includes an annular pressure containment structure useful for manipulating pipe during drilling and other well operations performed with annular pressure at the wellhead. The annular pressure containment structure includes a sealing structure involving a sealing wall and a fluid port extending through the sealing wall through with a hydrodynamic bearing fluid is injectable adjacent pipe received in the annular pressure containment structure.Type: ApplicationFiled: June 25, 2002Publication date: May 15, 2003Inventors: Maynard F. Ayler, Richard E. Andrews
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Patent number: 5566521Abstract: A concrete form mold unit formed of a lightweight, insulative material defines at least two rows of vertical core spaces, offset from each other. Concrete and reinforcing rods fill the core spaces, defining post structures. The top of the form mold unit is troughed and is filled with horizontal reinforcing rods and concrete, defining beam structures. The form mold units are laid in courses and stacked as required to build walls, with vertical cores and horizontal troughs aligned, producing an efficient utilization of concrete in the posts and beams. Each course is filled with concrete before the next course is added. The form mold unit is retained as an insulative part of the building structure, with a low dead load. Vertical attaching plates are placed on the surface of the wall, with penetrating fasteners passing into an underlying concrete post or beam. Surface finish materials are joined to the attaching plates.Type: GrantFiled: August 10, 1994Date of Patent: October 22, 1996Inventors: Richard E. Andrews, Mark E. Wilsey
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Patent number: 5059757Abstract: An electrode for a plasma carburizing furnace is disclosed which is adapted to provide a dynamic gas shroud for inhibiting the buildup of carbon soot on the insulating elements of the electrode. The reduction of carbon soot buildup on the insulating components dramatically reduces the frequency of electrical short-circuits across the insulating component, thereby increasing the availability of the furnace for processing of workpieces.Type: GrantFiled: November 24, 1989Date of Patent: October 22, 1991Assignee: Abar Ipsen Industries, Inc.Inventors: Trevor J. Law, Richard E. Andrews, Christopher A. Gall