Abstract: An automated age detection system employing a patient monitoring lead assembly and a patent monitoring device. In operation, the patient monitoring lead assembly conducts electrical activity of a heart of a patient to the patient monitoring device. In response thereto, the patient monitoring device classifying the patient as an adult patient or a pediatric patient as a function of electrocardiogram feature(s) derived from electrocardiogram measurement(s) of the electrical heart activity. The patient monitoring device may further estimate the age as a function of electrocardiogram feature(s). The classification facilitates an appropriate application of an adult analysis or a pediatric analysis of the electrical heart activity.

Abstract: A medical imaging system employs a transesophageal probe (20) including an ultrasound transducer (21) for scanning a patient's heart and atrial electrode(s) (22) for generating atrial electrocardiogram signal(s) predominately indicative of electrical activity of atrium chambers of the patient's heart. The medical imaging system further employs ventricular electrode(s) (23) for generating ventricular electrocardiogram signal(s) predominately indicative of electrical activity of ventricle chambers of the patient's heart. The medical imaging system further employs an electrocardiogram machine (30) for generating an electrocardiogram waveform based on the indicated electrical activities of the patient's heart, and for generating a cardiac gating signal representative of a cyclical cardiac phase period of the electrocardiogram waveform.

Abstract: When detecting ischemia and/or myocardial infarction in a subject, electrocardiogram (ECG) segments are analyzed for elevated ST segments indicative of ischemia and/or infarction. To mitigate false positive alerts, an ECG segment comprising an elevated ST segment that triggers an alert is presented to a clinician for verification as being indicative of ischemia or infarction, or as being attributable to a confounding condition not indicative of ischemia or infarction. Clinician feedback is used to adjust an elevated ST segment detection algorithm to improve accuracy and mitigate false positive alerts.

Abstract: The present invention relates to a device, system and method for sensor position guidance to guide a user or the subject to place a wearable sensor to the optimum position at the subject's body. The device comprises an image data input (40) for obtaining image data of at least a subject's body area showing motion of said body area, an analyzer (41) for analyzing the obtained image data to determine one or more locations of the body area showing maximal movement caused by respiration and/or heart beat, and a guidance output (42) for selecting from the determined one or more locations an optimum location based on the strength of movement and for providing guidance information indicating the optimum location, at which a wearable sensor (6) for monitoring respiration and/or heart rate should be placed to said subject's body.

Abstract: A physical monitoring system for monitoring and measuring a patient's respiration is described. The system includes one or more resistive or inductive respiration belts (110a, 10b), an electronic monitoring device (102) with a processor programmed to compute respiration and a module retainer (104) for accommodating the electronic monitoring device and securing the electronic monitoring device to the one or more resistive or inductive respiration belts. The system further includes electrocardiogram (ECG) electrodes (108) attached to or embedded in theone or more resistive or inductive respiration belts. The ECG electrodes are connected with the electronic monitoring module (102) via wires passing through the belts. The system can further include an accelerometer (204) integrated with one or more of the ECG electrodes that are attached to or embedded in theone or more resistive or inductive respiration belts.

Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for acute coronary syndrome and related disorders.

Abstract: A system for electrocardiogram (ECG) interpretation includes a processor and memory coupled to the processor. A rendering module is stored in the memory and is configured to receive input from an ECG and correlate interpretation statements with ECG measurements responsible for the interpretation statements in the ECG. An interface is configured to permit user selection of at least one interpretation statement in a display, the display being configured to render visual indications of the ECG measurements on digitally rendered waveforms of the ECG.

Abstract: When detecting ischemia and/or myocardial infarction in a subject, electrocardiogram (ECG) segments are analyzed for elevated ST segments indicative of ischemia and/or infarction. To mitigate false positive alerts, an ECG segment comprising an elevated ST segment that triggers an alert is presented to a clinician for verification as being indicative of ischemia or infarction, or as being attributable to a confounding condition not indicative of ischemia or infarction. Clinician feedback is used to adjust an elevated ST segment detection algorithm to improve accuracy and mitigate false positive alerts.

Abstract: A medical display system (16) and method display physiological signals. A physiological signal of a patient (14) is received, the physiological signal spanning a period of time. Signal quality of the physiological signal over the period of time is determined. An ECG signal (52) is displayed using a compressed time scale and the determined signal quality (54)n over time is displayed adjacent to the displayed physiological signal.

Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for acute coronary syndrome and related disorders.

Abstract: A medical imaging system employs a transesophageal probe (20) including an ultrasound transducer (21) for scanning a patient's heart and atrial electrode(s) (22) for generating atrial electrocardiogram signal(s) predominately indicative of electrical activity of atrium chambers of the patient's heart. The medical imaging system further employs ventricular electrode(s) (23) for generating ventricular electrocardiogram signal(s) predominately indicative of electrical activity of ventricle chambers of the patient's heart. The medical imaging system further employs an electrocardiogram machine (30) for generating an electrocardiogram waveform based on the indicated electrical activities of the patient's heart, and for generating a cardiac gating signal representative of a cyclical cardiac phase period of the electrocardiogram waveform.

Abstract: An ECG monitoring system continuously monitors a patient's ECG waveform and periodically identifies the patient's QT interval. QT interval values are averaged over time and a corrected interval value QTc and a change in QTc relative to a baseline, dQTc, are periodically produced. An alarm is responsive to updated QT interval values and issues an alarm whenever a selected QT value exceeds an alarm limit. The periodically produced QT interval values are stored and a trend display may be produced showing changes in the QT interval information over different periods of time. The trend display may selectively display the trend information either graphically or in tabular form.

Abstract: An automated age detection system employing a patient monitoring lead assembly and a patent monitoring device. In operation, the patient monitoring lead assembly conducts electrical activity of a heart of a patient to the patient monitoring device. In response thereto, the patient monitoring device classifying the patient as an adult patient or a pediatric patient as a function of electrocardiogram feature(s) derived from electrocardiogram measurement(s) of the electrical heart activity. The patient monitoring device may further estimate the age as a function of electrocardiogram feature(s). The classification facilitates an appropriate application of an adult analysis or a pediatric analysis of the electrical heart activity.

Abstract: A medical display system (16) and method display physiological signals. A physiological signal of a patient (14) is received, the physiological signal spanning a period of time. Signal quality of the physiological signal over the period of time is determined. An ECG signal (52) is displayed using a compressed time scale and the determined signal quality (54)n over time is displayed adjacent to the displayed physiological signal.

Abstract: An electrocardiogram (ECG) device includes a processor (114), a memory (116) coupled to the processor and an interface (120) configured to generate an edit window and configured to permit user input in the edit window. A type ahead module (124) is stored in the memory and is responsive to input entered in the edit window. The type ahead module is configured to predict a next word, phrase, interpretation code or category being input by a user based on a subset of alphanumeric key strokes and a context probability associated with a list of possible ECG entries. A report review and edit module (128) may also be stored in the memory. The report review and edit module is configured to update a severity of an ECG report based upon current ECG interpretation statements and rules in accordance with an access or edit operation by an operator.

Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for Rett syndrome.

Abstract: A system for electrocardiogram (ECG) interpretation includes a processor and memory coupled to the processor. A rendering module is stored in the memory and is configured to receive input from an ECG and correlate interpretation statements with ECG measurements responsible for the interpretation statements in the ECG. An interface is configured to permit user selection of at least one interpretation statement in a display, the display being configured to render visual indications of the ECG measurements on digitally rendered waveforms of the ECG.

Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for skin cancers.

Abstract: The segments of an anatomically corresponding bull's eye graph familiar to echocardiologists is annotated by coloring those segments for which ECG data indicates the presence of myocardial infarction injury. In an illustrated example, segments are colored with a second color when the ECG data corresponding to those segments are indicated as being the site of a coronary occlusion. The segments of the bull's eye graph may be colored in a third color with the results of a diagnostic imaging exam, such as by coloring segments exhibiting wall motion abnormalities with a third color.

Abstract: An atrial fibrillation (AF) monitor extracts two P wave features and an R-R interval feature from a sequence of ECG waveforms. The features are used by a classifier to classify a heart rhythm as AF or non-AF. The AF classification results may be further processed to reduce false alarm reporting. The AF classification results are used by an AF burden calculator to report AF burden in real time.