Patents by Inventor Richard E. H. Wettenhall

Richard E. H. Wettenhall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody having binding specificity to parathyroid hormone related protein (PTHrP) and kit comprising the same
    Patent number: 5872221
    Abstract: Antibody reagents capable of binding epitopes of PTHrP and a kit for the detection of PTHrP or fragments thereof comprising one or more antibody reagents capable of binding to epitopes of PTHrP.
    Type: Grant
    Filed: January 25, 1993
    Date of Patent: February 16, 1999
    Assignee: The University of Melbourne
    Inventors: Thomas J. Martin, Jane M. Moseley, Bruce E. Kemp, Richard E. H. Wettenhall
  • Protein active in humoral hypercalcemia of malignancy-PTHrP
    Patent number: 5703207
    Abstract: A sub-unit or fragment of parathyroid hormone related protein having the following characteristics:(a) an N-terminal amino acid sequence A V S E H Q L L H D K G K S I Q D L R R R F F L H H L I A E I H T A E I R A T S E V S P N;(b) a molecular weight between 15 to 25 kilodaltons, as determined by sodium dodecyl polyacrylamide gel electrophoresis under reducing and non-reducing conditions; and(c) a specific biological activity of at least about 6 mg equivalents of a peptide composed of amino acids 1-34 a parathyroid hormone related protein per mg protein as measured in an adenylate cyclase response assay.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: December 30, 1997
    Assignee: The University of Melbourne
    Inventors: Thomas J. Martin, Jane M. Moseley, Bruce E. Kemp, Richard E. H. Wettenhall
  • Single chain proteins with FHS suppressing activity isolated from follicular fluid and uses thereof
    Patent number: 5470826
    Abstract: Polypeptides exhibiting an inhibitory action over follitropin are disclosed. These polypeptides are designated follitropin suppressing proteins, or "FSP's," and range in size from 30 to 60 kD as determined by SDS-PAGE. Uses for FSP's, including regulation of fertility and as immunogens, are disclosed.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: November 28, 1995
    Assignees: Biotechnology Australia Pty Ltd., Monash University, Monash Medical Centre, St. Vincents Institute of Medical Research
    Inventors: David M. De Kretser, Henry G. Burger, Milton T. W. Hearn, David M. Milne-Robertson, Richard E. H. Wettenhall, Robert I. McLachlan, Fiona De Vos
  • Protein active in humoral hypercalcemia of malignancy-PthrP
    Patent number: 5460978
    Abstract: Substantially pure parathyroid hormone related protein (PTHrP) active in humoral hypercalcemia of malignancy and sub-units and fragments thereof. Antibody reagents capable of binding to epitopes of PTHrP. Methods and kits for the detection of PTHrP.
    Type: Grant
    Filed: June 14, 1991
    Date of Patent: October 24, 1995
    Assignee: The University of Melbourne
    Inventors: Thomas J. Martin, Jane M. Moseley, Bruce E. Kemp, Richard E. H. Wettenhall
  • Protein active in humoral hypercalcemia of malignancy-PTHRP
    Patent number: 5116952
    Abstract: Substantially pure proteins active in humoral hypercalcemia of malignancy (PTHrP) and sub-units and fragments thereof. Antibody reagents capable of binding to epitopes of PTHrP. Methods and kits for the detection of PTHrP.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: May 26, 1992
    Assignee: The University of Melbourne
    Inventors: Thomas J. Martin, Jane M. Moseley, Bruce E. Kemp, Richard E. H. Wettenhall