Patents by Inventor Richard E. Kaufman
Richard E. Kaufman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200391013Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: ApplicationFiled: August 28, 2020Publication date: December 17, 2020Inventors: Richard E. KAUFMAN, John Joseph STANKUS, James SU
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Patent number: 10814108Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: GrantFiled: February 13, 2020Date of Patent: October 27, 2020Assignee: Intersect ENT, Inc.Inventors: Richard E. Kaufman, John Joseph Stankus, James Su
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Publication number: 20200179659Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: ApplicationFiled: February 13, 2020Publication date: June 11, 2020Inventors: Richard E. KAUFMAN, John Joseph STANKUS, James SU
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Patent number: 10603473Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: GrantFiled: July 26, 2019Date of Patent: March 31, 2020Assignee: Intersect ENT, Inc.Inventors: Richard E. Kaufman, John Joseph Stankus, James Su
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Publication number: 20200016377Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: ApplicationFiled: July 26, 2019Publication date: January 16, 2020Inventors: Richard E. KAUFMAN, John Joseph STANKUS, James SU
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Patent number: 10441757Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: GrantFiled: January 22, 2016Date of Patent: October 15, 2019Assignee: Intersect ENT, Inc.Inventors: Richard E. Kaufman, John Joseph Stankus, James Su
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Patent number: 9782283Abstract: Described here are devices and methods for crimping self-expanding devices. The crimping devices may be useful for crimping a variety of different self-expanding devices (whether such devices are biodegradable or bio-durable). The crimping devices may have crimping members to engage the self-expanding device to reduce the device from an expanding configuration to an unexpanded configuration. The crimping member may comprise or include a suture, wire, ribbon, guiding hoop, pusher, prong, holding bar, balloon, jaws, combinations thereof, or the like. The crimping devices may also include or comprise a holding structure to hold the self-expanding device in an unexpanded or expanded configuration.Type: GrantFiled: June 6, 2014Date of Patent: October 10, 2017Assignee: Intersect ENT, Inc.Inventors: Anthony J. Abbate, Bin Huang, Gail M. Zaler, David C. Gale, Richard E. Kaufman, Vijaykumar Rajasekhar
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Publication number: 20160354587Abstract: Described here are devices and methods for dilating tissues. In other variations, the dilatation device comprises a slotted or expandable tube that may expand to dilate tissue. In still other variations, the dilatation device comprises two or more hinged or movable plate members that separate to dilate tissue. In yet other variations, the dilation device may comprise one or more flexible members. One or more portions of the dilatation device may be detachable from the device in the body, and dilatation device may release one or more implants into the body. In some of these variations, the dilatation device may additionally be used to expand one or more implants or other devices within the body. In some variations the dilatation device may release one or more substances that may hold dilated tissue in a dilated configuration.Type: ApplicationFiled: August 18, 2016Publication date: December 8, 2016Inventors: Anthony J. ABBATE, Gail M. ZALER, Richard E. KAUFMAN, David C. GALE, Bin HUANG, Susan P. STIMSON
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Patent number: 9446225Abstract: Described here are devices and methods for dilating tissues. In other variations, the dilatation device comprises a slotted or expandable tube that may expand to dilate tissue. In still other variations, the dilatation device comprises two or more hinged or movable plate members that separate to dilate tissue. In yet other variations, the dilation device may comprise one or more flexible members. One or more portions of the dilatation device may be detachable from the device in the body, and dilatation device may release one or more implants into the body. In some of these variations, the dilatation device may additionally be used to expand one or more implants or other devices within the body. In some variations the dilatation device may release one or more substances that may hold dilated tissue in a dilated configuration.Type: GrantFiled: January 25, 2010Date of Patent: September 20, 2016Assignee: INTERSECT ENT, INC.Inventors: Anthony J. Abbate, Gail M. Zaler, Richard E. Kaufman, David C. Gale, Bin Huang, Susan P. Stimson
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Publication number: 20160213890Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.Type: ApplicationFiled: January 22, 2016Publication date: July 28, 2016Inventors: Richard E. KAUFMAN, John Joseph STANKUS, James SU
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Patent number: 8986341Abstract: Described here are self-expanding devices and methods of using and making them. The devices may be useful in a variety of locations within the body, for a number of different uses. In some variations, the devices have a first compressed configuration enabling low profile delivery through a delivery device, a second expanded configuration for apposition against tissue, and comprise either a single continuous filament or at least two non-intersecting filaments. In some variations, the device is formed into a shape having a series of peaks and valleys. At least one of the peaks and valleys may have a loop at then end thereof. At least a portion of these devices may be capable of biodegrading over a predetermined period of time, and the devices may be configured for drug delivery. Methods of treating one or more sinus cavities are also described here.Type: GrantFiled: November 15, 2013Date of Patent: March 24, 2015Assignee: Intersect ENT, Inc.Inventors: Anthony J. Abbate, Bin Huang, Gail M. Zaler, David C. Gale, Richard E. Kaufman
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Publication number: 20150081017Abstract: Described here are self-expanding devices and methods of using and making them. The devices may be useful in a variety of locations within the body, for a number of different uses. In some variations, the devices have a first compressed configuration enabling low profile delivery through a delivery device, a second expanded configuration for apposition against tissue, and comprise either a single continuous filament or at least two non-intersecting filaments. In some variations, the device is formed into a shape having a series of peaks and valleys. At least one of the peaks and valleys may have a loop at then end thereof. At least a portion of these devices may be capable of biodegrading over a predetermined period of time, and the devices may be configured for drug delivery. Methods of treating one or more sinus cavities are also described here.Type: ApplicationFiled: November 21, 2014Publication date: March 19, 2015Inventors: Anthony J. ABBATE, Bin HUANG, Gail M. ZALER, David C. GALE, Richard E. KAUFMAN
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Publication number: 20140283349Abstract: Described here are devices and methods for crimping self-expanding devices. The crimping devices may be useful for crimping a variety of different self-expanding devices (whether such devices are biodegradable or bio-durable). The crimping devices may have crimping members to engage the self-expanding device to reduce the device from an expanding configuration to an unexpanded configuration. The crimping member may comprise or include a suture, wire, ribbon, guiding hoop, pusher, prong, holding bar, balloon, jaws, combinations thereof, or the like. The crimping devices may also include or comprise a holding structure to hold the self-expanding device in an unexpanded or expanded configuration.Type: ApplicationFiled: June 6, 2014Publication date: September 25, 2014Inventors: Anthony J. ABBATE, Bin HUANG, Gail M. ZALER, David C. GALE, Richard E. KAUFMAN, Vijaykumar RAJASEKHAR
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Patent number: 8763222Abstract: Described here are devices and methods for crimping self-expanding devices. The crimping devices may be useful for crimping a variety of different self-expanding devices (whether such devices are biodegradable or bio-durable). The crimping devices may have crimping members to engage the self-expanding device to reduce the device from an expanding configuration to an unexpanded configuration. The crimping member may comprise or include a suture, wire, ribbon, guiding hoop, pusher, prong, holding bar, balloon, jaws, combinations thereof, or the like. The crimping devices may also include or comprise a holding structure to hold the self-expanding device in an unexpanded or expanded configuration.Type: GrantFiled: July 30, 2009Date of Patent: July 1, 2014Assignee: Intersect ENT, Inc.Inventors: Anthony J. Abbate, Bin Huang, Gail M. Zaler, David C. Gale, Richard E. Kaufman, Vijaykumar Rajasekhar
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Publication number: 20140154236Abstract: Described here are devices and methods for treating one or more conditions or symptoms associated with a tonsil procedure. In some variations, a drug-releasing device may be at least partially delivered to one or more tonsillar tissues before, during, or after a tonsil procedure. In some variations, the drug-releasing device may be configured to be biodegradable. In other variations, the drug-releasing device may comprise one or more hemostatic materials or one or more adhesives. The drug-releasing device may be configured to release one or more drugs or agents, such as, for example, one or more analgesics, local anesthetics, vasoconstrictors, antibiotics, combinations thereof and the like.Type: ApplicationFiled: February 6, 2014Publication date: June 5, 2014Applicant: INTERSECT ENT, INC.Inventors: Jerome E. HESTER, Anthony J. ABBATE, Richard E. KAUFMAN, David C. GALE, Gail M. ZALER, Bin HUANG, Lisa EARNHARDT, Vijaykumar RAJASEKHAR
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Publication number: 20140074238Abstract: Described here are self-expanding devices and methods of using and making them. The devices may be useful in a variety of locations within the body, for a number of different uses. In some variations, the devices have a first compressed configuration enabling low profile delivery through a delivery device, a second expanded configuration for apposition against tissue, and comprise either a single continuous filament or at least two non-intersecting filaments. In some variations, the device is formed into a shape having a series of peaks and valleys. At least one of the peaks and valleys may have a loop at then end thereof. At least a portion of these devices may be capable of biodegrading over a predetermined period of time, and the devices may be configured for drug delivery. Methods of treating one or more sinus cavities are also described here.Type: ApplicationFiled: November 15, 2013Publication date: March 13, 2014Applicant: Intersect ENT, Inc.Inventors: Anthony J. ABBATE, Bin HUANG, Gail M. ZALER, David C. GALE, Richard E. KAUFMAN
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Patent number: 8663192Abstract: Described here are devices and methods for treating one or more conditions or symptoms associated with a tonsil procedure. In some variations, a drug-releasing device may be at least partially delivered to one or more tonsillar tissues before, during, or after a tonsil procedure. In some variations, the drug-releasing device may be configured to be biodegradable. In other variations, the drug-releasing device may comprise one or more hemostatic materials or one or more adhesives. The drug-releasing device may be configured to release one or more drugs or agents, such as, for example, one or more analgesics, local anesthetics, vasoconstrictors, antibiotics, combinations thereof and the like.Type: GrantFiled: April 27, 2010Date of Patent: March 4, 2014Assignee: Intersect ENT, Inc.Inventors: Jerome E. Hester, Anthony J. Abbate, Richard E. Kaufman, David C. Gale, Gail M. Zaler, Bin Huang, Lisa Earnhardt, Vijaykumar Rajasekhar
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Patent number: 8585731Abstract: Described here are self-expanding devices and methods of using and making them. The devices may be useful in a variety of locations within the body, for a number of different uses. In some variations, the devices have a first compressed configuration enabling low profile delivery through a delivery device, a second expanded configuration for apposition against tissue, and comprise either a single continuous filament or at least two non-intersecting filaments. In some variations, the device is formed into a shape having a series of peaks and valleys. At least one of the peaks and valleys may have a loop at then end thereof. At least a portion of these devices may be capable of biodegrading over a predetermined period of time, and the devices may be configured for drug delivery. Methods of treating one or more sinus cavities are also described here.Type: GrantFiled: December 12, 2008Date of Patent: November 19, 2013Assignee: Intersect ENT, Inc.Inventors: Anthony J. Abbate, Bin Huang, Gail M. Zaler, David C. Gale, Richard E. Kaufman
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Publication number: 20110112513Abstract: Described here are devices and methods for treating one or more conditions or symptoms associated with a tonsil procedure. In some variations, a drug-releasing device may be at least partially delivered to one or more tonsillar tissues before, during, or after a tonsil procedure. In some variations, the drug-releasing device may be configured to be biodegradable. In other variations, the drug-releasing device may comprise one or more hemostatic materials or one or more adhesives. The drug-releasing device may be configured to release one or more drugs or agents, such as, for example, one or more analgesics, local anesthetics, vasoconstrictors, antibiotics, combinations thereof and the like.Type: ApplicationFiled: April 27, 2010Publication date: May 12, 2011Inventors: Jerome E. Hester, Anthony J. ABBATE, Richard E. KAUFMAN, David C. GALE, Gail M. ZALER, Bin HUANG, Lisa EARNHARDT, Vijaykumar RAJASEKHAR
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Publication number: 20100211093Abstract: Described here are devices and methods for dilating tissues. In other variations, the dilatation device comprises a slotted or expandable tube that may expand to dilate tissue. In still other variations, the dilatation device comprises two or more hinged or movable plate members that separate to dilate tissue. In yet other variations, the dilation device may comprise one or more flexible members. One or more portions of the dilatation device may be detachable from the device in the body, and dilatation device may release one or more implants into the body. In some of these variations, the dilatation device may additionally be used to expand one or more implants or other devices within the body. In some variations the dilatation device may release one or more substances that may hold dilated tissue in a dilated configuration.Type: ApplicationFiled: January 25, 2010Publication date: August 19, 2010Inventors: Anthony J. Abbate, Gail M. Zaler, Richard E. Kaufman, David C. Gale, Bin Huang, Susan P. Stimson