Patents by Inventor Richard E. L. Henderson

Richard E. L. Henderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N.sup.6 -[(2-Hydroxypropyl)aryl]adenosines
    Patent number: 4388308
    Abstract: N.sup.6 -2-hydroxypropylaryl-substituted adenosines and adenines represented by the formula ##STR1## wherein R.sub.1 is selected from the group consisting of naphthyl, phenyl, substituted phenyl or biphenyl; and R.sub.2 is hydrogen or 1-.beta.-ribosyl; and the pharmaceutically acceptable salts thereof. The compounds are anti-hypertensive agents.
    Type: Grant
    Filed: June 9, 1980
    Date of Patent: June 14, 1983
    Assignee: G.D. Searle & Co.
    Inventors: Robert W. Hamilton, Richard E. L. Henderson, Barnett S. Pitzele
  • Anti-ulcer urea compounds
    Patent number: 4386211
    Abstract: The invention relates to certain urea derivatives of the formula R.sub.1 CH.sub.2 S(CH.sub.2).sub.2 NHCONHR.sub.2 where R.sub.1 are certain furanyls, imidazoles and thiazolyls and R.sub.2 are certain imidazoles and thiazolyls. These compounds are H-2 histamine receptor inhibitors and therefore useful in the treatment of ulcers.
    Type: Grant
    Filed: August 25, 1981
    Date of Patent: May 31, 1983
    Assignee: G. D. Searle & Co.
    Inventors: Richard E. L. Henderson, Barnett S. Pitzele
  • N.sup.6 -Substituted adenosines
    Patent number: 4340730
    Abstract: Novel N.sup.6 -adenosines according to formula I are disclosed. These novel compounds are useful as antihypertensive agents.
    Type: Grant
    Filed: January 30, 1981
    Date of Patent: July 20, 1982
    Assignee: G. D. Searle & Co.
    Inventors: Richard E. L. Henderson, Nancy J. Malek, Alan E. Moormann, Barnett S. Pitzele