Abstract: The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene switch construct that controls expression of one or more therapeutic products.

Abstract: The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene switch construct that controls expression of one or more therapeutic products.

Abstract: The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene switch construct that controls expression of one or more therapeutic products.

Abstract: The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene switch construct that controls expression of one or more therapeutic products.

Abstract: The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene switch construct that controls expression of one or more therapeutic products.

Abstract: The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis.

Abstract: The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis.

Abstract: The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis.

Abstract: A building panel for attachment to exterior and interior building surfaces, the panel including a casting layer having at least one imbedded reinforcing layer, at least one attachment means extending through the casting layer and imbedded reinforcing layer for attachment to a building frame, and a finishing layer adjacent to the casting layer, the finishing layer being positioned to cover a first end of the at least one attachment means.

Abstract: The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis.

Abstract: The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene switch construct that controls expression of one or more therapeutic products.

Abstract: A seal assembly adapted for use in creating a seal between an axially extending shaft and a support member. The seal assembly defines an axial passage through which the shaft extends, wherein a bearing assembly is mounted to the support member and includes a stationary outer race and an inner race which rotates along with the shaft. The seal assembly includes a rigid ring defining an axial passage through which the shaft extends and a resilient material carried by the ring. The resilient material defines an inner sealing section adapted to engage the shaft and an outer sealing section located radially outwardly of the inner sealing section and adapted to engage an outer sealing surface associated with the support member.

Abstract: Preparation, use, and structure of endogenous Ah receptor ligand is disclosed.

Abstract: A building panel for attachment to exterior and interior building surfaces, the panel including a casting layer having at least one imbedded reinforcing layer, at least one attachment means extending through the casting layer and imbedded reinforcing layer for attachment to a building frame, and a finishing layer adjacent to the casting layer, the finishing layer being positioned to cover a first end of the at least one attachment means.

Abstract: A computerized information retrieval system having consistency among a sensory network portrayed in a visual display, a semantic network that establishes the logic of data organization and retrieval and a mechanical storage network that locates data in a memory structure the networks having an architecture based on a life tree array that splits the search and storage paths into multiple paths for rapid access and retrieval in response to user queries.

Abstract: A bar code schema for identification of solid form drugs, such as pills, tablets, capsules and the like using a data matrix type symbology for compact coding that is easily deciphered in combination with a common visual symbol that is easily recognized, the schema incorporating a portable code reading pen.

Abstract: Preparation, use, and structure of endogenous Ah receptor ligand is disclosed.

Abstract: A method executed in a computer system for detecting and handling an invalid use of a data structure is described. The method includes the steps of providing a data structure associated with a first computing environment. The data structure includes a field having a value stored therein identifying an inaccessible address in a second computing environment. This field is used in detecting an invalid use of the data structure in the second computing environment by a computer program attempting to access memory using said inaccessible address indicated by said value contained in the first field. Additionally a preferred data structure is described as are alternative embodiments of detecting an invalid use of a data structure.

Abstract: A computerized information retrieval system having consistency among a sensory network portrayed in a visual display, a semantic network that establishes the logic of data organization and retrieval and a mechanical storage network that locates data in a memory structure the networks having an architecture based on a life tree array that splits the search and storage paths into multiple paths for rapid access and retrieval in response to user queries.