Patents by Inventor Richard E. Rolleston

Richard E. Rolleston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tc99m-Phenida, radioscintigraphic agent for diagnosis of hepatoniliary disease
    Patent number: 4454107
    Abstract: This invention relates to novel derivatives of imino diacetic acid of the formula: ##STR1## wherein R.sup.1 is selected from the group consisting of: ##STR2## wherein X is halo (chloro, bromo or iodo) and R.sup.2 is lower alkyl of from 1-5 carbon atoms. It also relates to a novel diagnostic kit for hepatobiliary imaging comprising ingredients employed in the intravenous injection of a complex of technetium 99m, and an imino diacetic acid of the above formula. It also relates to a process for preparing said compounds by reaction of nitrilotriacetic acid anhydride and an amine of the formula R.sup.1 NH.sub.2 wherein R.sup.1 is as defined hereinabove.
    Type: Grant
    Filed: August 30, 1982
    Date of Patent: June 12, 1984
    Assignee: Merck & Co., Inc.
    Inventor: Richard E. Rolleston
  • Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)
    Patent number: 4187284
    Abstract: This invention relates to a novel diagnostic kit for use in radiographic bone scanning. More particularly, it relates to a kit comprising ingredients employed in the preparation of an intravenous injection of a complex of Technetium-99m, stannous ion, and an organic phosphonate identified as triethylene tetramine hexa (methylene phosphonic acid).
    Type: Grant
    Filed: October 3, 1977
    Date of Patent: February 5, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Richard E. Rolleston, Jacques A. Nadeau