Abstract: Compounds of the class including 4-methyl-5-(unsubstituted and substituted henoxy)-6-methoxy-8-(aminoalkylamino)quinolines as the free bases and pharmaceutically acceptable acid amine salts are described. The compounds are highly effective antimalarial agents which possess, surprisingly, both tissue schizonticidal (radical curative) and blood schizonticidal (suppressive) activity. In addition, these drugs have significantly better therapeutics indices than primaquine which is the current tissue schizonticidal drug of choice. Primaquine possesses no useful blood schizonticidal activity at tolerated dose levels.

Abstract: The motion detector described in this disclosure is an apparatus for monitoring the minute movements made by the body during the process of breathing. This is accomplished by converting the body movements into electrical signals with an adapted piezoelectric transducer. This electrical signal is used to restart a counting circuit which uses a variable free running Schmitt-trigger oscillator signal for counting. The output of the counting circuit is connected to an audio alarm through a switch. This switch also connects the Schmitt-trigger oscillator to the audio alarm when the low voltage detector circuit indicates that the supply voltage has dropped below a predetermined level.