Abstract: Described herein are benzoxazepin oxazolidinone compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.

Abstract: Described herein are benzoxazepin oxazolidinone compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.

Abstract: Described herein are benzoxazepin oxazolidinone compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.

Abstract: Content filtering of data containers of multiple content types is performed using multiple filtering modules operating concurrently. An apparatus for content filtering has a set of content-specific filtering modules and a network interface for parsing a received data container into components and directing each component to a respective filtering module. A filtering module edits a component of a specific content type according to respective rules. A multiplexer combines edited components produced by the set of filtering modules to form an edited data container. A root module applies a set of basic rules to a data container and any attachments. In an alternative configuration, the apparatus employs multiple filtering modules each applying rules for all content types. Received data containers are distributed among the filtering modules and an output module arranges edited data containers of a data stream in proper sequential order.

Abstract: An insect swatter formed from a plurality of limp fibers into a handle portion and a striking portion is provided. The handle portion is formed by the portion of the limp fibers that are braided together, while the striking portion is formed from the remaining portion of the limp fibers that is left unbraided. The limp fibers are made from material that exhibits a limp, soft and resilient manner for delivering a soft impact while also exhibiting properties tolerant to shape changes, for instance, when for fitting into tight spaces.

Abstract: A dispensing system and associated method provides a turnkey solution for dispensing pharmaceutical products such as solid medications and nutritional supplements to be taken orally in health care settings, including but not limited to long term care (LTC) and assisted living settings.

Abstract: Content filtering of data containers of multiple content types is performed using multiple filtering modules operating concurrently. An apparatus for content filtering has a set of content-specific filtering modules and a network interface for parsing a received data container into components and directing each component to a respective filtering module. A filtering module edits a component of a specific content type according to respective rules. A multiplexer combines edited components produced by the set of filtering modules to form an edited data container. A root module applies a set of basic rules to a data container and any attachments. In an alternative configuration, the apparatus employs multiple filtering modules each applying rules for all content types. Received data containers are distributed among the filtering modules and an output module arranges edited data containers of a data stream in proper sequential order.

Abstract: An unmanned, autonomous, ocean-going vessel including a primary hull and a rigid wing rotationally coupled with the primary hull that freely rotates about a rotational axis. At least one of the primary hull and the rigid wing includes at least one selectively floodable compartment configured to selectively flood to submerge the primary hull and at least a portion of the rigid wing. The vessel further includes at least one controller configured to maintain a desired heading. The vessel further includes a control surface element configured to aerodynamically control a wing angle of the rigid wing based on a force exerted by wind on the control surface element. The vessel further includes a rudder. The at least one controller is further configured to determine a rudder position and generate a signal to position the rudder. The vessel further includes a keel coupled with the primary hull.

Abstract: A high-tailed wing sail is provided. A wing sail device includes a wing body including a wing tip and a wing base configured to rotationally couple with a vessel. The wing body is configured to freely rotate with respect to the vessel about a rotational axis. The wing sail device further includes a wing tail coupled to the wing body such that a top end of the wing tail is higher than the wing tip of the wing body.

Abstract: A high-tailed wing sail is provided. A wing sail device includes a wing body including a wing tip and a wing base configured to rotationally couple with a vessel. The wing body is configured to freely rotate with respect to the vessel about a rotational axis. The wing sail device further includes a wing tail coupled to the wing body such that a top end of the wing tail is higher than the wing tip of the wing body.

Abstract: A system for assembling and dispensing an order made up of one or more individually packaged items from a plurality of different individually packaged items includes a storage module containing one or more packages of each of the items, and a conveyor having selectively assignable spaces configured to receive the packaged items associated with a particular order and to transport the packaged items to a processing location. A pick device is movable relative to the storage module and is configured to retrieve a package from the storage module. A transfer station adjacent the conveyor receives one or more of the packaged items from the pick device and an actuator associated with the transfer station moves the packaged items from the transfer station to the conveyor when the assigned space associated with the order is in the registration with the transfer station.

Abstract: An electric vehicle service equipment (EVSE) system includes an EVSE case having a front plug face, a rear face, and left and right gripping sides that collectively define a trapezoidal prism cross section, the left and right gripping sides further having left and right convex gripping portions, respectively, a relay positioned within the EVSE case, and a controller positioned within the EVSE case and in communication with the relay, the controller responsive to a pilot duty signal, when a pilot duty signal is present.

Abstract: Benzoxazepin Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Abstract: An unmanned ocean-going vessel including a primary hull, a rigid wing rotationally coupled with the primary hull where the rigid wing freely rotates about a rotational axis of the rigid wing, a controller configured to maintain a desired heading, a control surface element configured to aerodynamically control a wing angle of the rigid wing based on a position of the control surface element, where the controller is configured to determine a control surface angle and generate a signal to position the control surface element based on the control surface angle, a rudder, where the controller is further configured to determine a rudder position and generate a signal to position the rudder to the rudder position, and a keel including ballast sufficient to provide a positive righting moment sufficient to cause the primary hull to passively right from any position.

Abstract: A method for conditioning multimedia containers to be compatible with decoding facilities of receivers of diverse types is disclosed. Content of a multimedia container may include components of different encoding formats. Container conditioning also detects and, where feasible, removes undesirable insertions within each content component of a multimedia container. A content component of a container may be filtered, re-encoded, or deleted. Notifications indicating conditions of a container and any modifications performed are appended to the container. A notification may be presented in at least one form compatible with characteristics of a respective receiver. An editing engine implementing the method is associated with a network entity to which multimedia containers are directed. The editing engine accesses a receiver database storing information on several types of receivers and a repository of notification templates encoded in several forms.

Abstract: A method and system are disclosed for adapting the media contained in a multimedia messaging service (MMS) message, which may include a presentation, into a single media format such as an audio/video file or stream by creating a logical timeline from information found in the presentation, creating an adaptation pipeline from the logical timeline, and executing the adaptation pipeline.

Abstract: A method for conditioning multimedia containers to be compatible with decoding facilities of receivers of diverse types is disclosed. Content of a multimedia container may include components of different encoding formats. Container conditioning also detects and, where feasible, removes undesirable insertions within each content component of a multimedia container. A content component of a container may be filtered, re-encoded, or deleted. Notifications indicating conditions of a container and any modifications performed are appended to the container. A notification may be presented in at least one form compatible with characteristics of a respective receiver. An editing engine implementing the method is associated with a network entity to which multimedia containers are directed. The editing engine accesses a receiver database storing information on several types of receivers and a repository of notification templates encoded in several forms.

Abstract: A method for conditioning multimedia containers to be compatible with decoding facilities of receivers of diverse types is disclosed. Content of a multimedia container may include components of different encoding formats. Container conditioning also detects and, where feasible, removes undesirable insertions within each content component of a multimedia container. A content component of a container may be filtered, re-encoded, or deleted. Notifications indicating conditions of a container and any modifications performed are appended to the container. A notification may be presented in at least one form compatible with characteristics of a respective receiver. An editing engine implementing the method is associated with a network entity to which multimedia containers are directed. The editing engine accesses a receiver database storing information on several types of receivers and a repository of notification templates encoded in several forms.

Abstract: Content filtering of data containers of multiple content types is performed using multiple filtering modules operating concurrently. An apparatus for content filtering has a set of content-specific filtering modules and a network interface for parsing a received data container into components and directing each component to a respective filtering module. A filtering module edits a component of a specific content type according to respective rules. A multiplexer combines edited components produced by the set of filtering modules to form an edited data container. A root module applies a set of basic rules to a data container and any attachments. In an alternative configuration, the apparatus employs multiple filtering modules each applying rules for all content types. Received data containers are distributed among the filtering modules and an output module arranges edited data containers of a data stream in proper sequential order.

Abstract: Content filtering of data containers of multiple content types is performed using multiple filtering modules operating concurrently. An apparatus for content filtering has a set of content-specific filtering modules and a network interface for parsing a received data container into components and directing each component to a respective filtering module. A filtering module edits a component of a specific content type according to respective rules. A multiplexer combines edited components produced by the set of filtering modules to form an edited data container. A root module applies a set of basic rules to a data container and any attachments. In an alternative configuration, the apparatus employs multiple filtering modules each applying rules for all content types. Received data containers are distributed among the filtering modules and an output module arranges edited data containers of a data stream in proper sequential order.