Patents by Inventor Richard Essner

Richard Essner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immune modulating genes for prognosis, diagnosis and treatment of metastatic disease, and drug identification methods thereof
    Patent number: 11603569
    Abstract: Immune-modulating genes are provided for prognosis and diagnosis of metastases or reoccurrence of cancer, as well as methods of prognosis, diagnosis, prophylaxis and treatment of cancer metastases.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: March 14, 2023
    Assignee: Cedars-Sinai Medical Center
    Inventor: Richard Essner
  • IMMUNE MODULATING GENES FOR PROGNOSIS, DIAGNOSIS AND TREATMENT OF METASTATIC DISEASE, AND DRUG IDENTIFICATION METHODS THEREOF
    Publication number: 20190292604
    Abstract: Immune-modulating genes are provided for prognosis and diagnosis of metastases or reoccurrence of cancer, as well as methods of prognosis, diagnosis, prophylaxis and treatment of cancer metastases.
    Type: Application
    Filed: March 20, 2019
    Publication date: September 26, 2019
    Applicant: Cedars-Sinai Medical Center
    Inventor: Richard Essner
  • Treatment of cancer and compositions
    Patent number: 9156898
    Abstract: The invention discloses a method of identifying a gene associated with stage III primary cancer or lymph node metastasis. The genes so identified include CAV1, CST3, LIMK1, MMP2, MMP15, VEGF, ETV4, MMP9, PIK3C2B, and SERPIN1. Also disclosed are methods for diagnosis, prognosis, and treatment of cancer. The invention further discloses compositions for preventing and treating diseases.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: October 13, 2015
    Assignee: John Wayne Cancer Institute
    Inventor: Richard Essner
  • TREATMENT OF CANCER AND COMPOSITIONS
    Publication number: 20120258056
    Abstract: The invention discloses a method of identifying a gene associated with stage III primary cancer or lymph node metastasis. The genes so identified include CAV1, CST3, LIMK1, MMP2, MMP15, VEGF, ETV4, MMP9, PIK3C2B, and SERPIN1. Also disclosed are methods for diagnosis, prognosis, and treatment of cancer. The invention further discloses compositions for preventing and treating diseases.
    Type: Application
    Filed: September 23, 2011
    Publication date: October 11, 2012
    Inventor: Richard Essner
  • Method and instrument for minimally invasive sentinel lymph node location and biopsy
    Patent number: 7653427
    Abstract: The present invention is directed to instruments and instrumental techniques for locating cancer cells in lymph nodes which utilize a radiation detector operatively connected to an ultrasound probe for locating the exact position of radiation tagged tissue, particularly in sentinel lymph nodes followed by placement of a biopsy device. Also described are unique new interoperative radiation detection probes for use in these techniques which include structure for placement of a biopsy device or biopsy needle into the located lymph node and procedures for removal of small portions of detected radiation emitting sentinel lymph nodes for evaluation in a pathology laboratory by measurement of expressed genes located in the removed tissue. The instruments and instrumental techniques also facilitate the subsequent delivery of materials to reverse the unfavorable immune response or environment conducive for metastasis in the sentinel lymph node once cancer cells are located therein.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: January 26, 2010
    Assignee: Intra-Medical Imaging LLC
    Inventors: Richard Essner, Farhad Daghighian, Henry Daghighian
  • Treatment of cancer and compositions
    Publication number: 20060134661
    Abstract: The invention discloses a method of identifying a gene associated with stage III primary cancer or lymph node metastasis. The genes so identified include CAV1, CST3, LIMK1, MMP2, MMP15, VEGF, ETV4, MMP9, PIK3C2B, and SERPIN1. Also disclosed are methods for diagnosis, prognosis, and treatment of cancer. The invention further discloses compositions for preventing and treating diseases.
    Type: Application
    Filed: October 12, 2005
    Publication date: June 22, 2006
    Inventor: Richard Essner
  • Method and instrument for minimally invasive sentinel lymph node location and biopsy
    Publication number: 20060106306
    Abstract: The present invention is directed to instruments and instrumental techniques for locating cancer cells in lymph nodes which utilize a radiation detector operatively connected to an ultrasound probe for locating the exact position of radiation tagged tissue, particularly in sentinel lymph nodes followed by placement of a biopsy device. Also described are unique new interoperative radiation detection probes for use in these techniques which include structure for placement of a biopsy device or biopsy needle into the located lymph node and procedures for removal of small portions of detected radiation emitting sentinel lymph nodes for evaluation in a pathology laboratory by measurement of expressed genes located in the removed tissue. The instruments and instrumental techniques also facilitate the subsequent delivery of materials to reverse the unfavorable immune response or environment conducive for metastasis in the sentinel lymph node once cancer cells are located therein.
    Type: Application
    Filed: November 10, 2005
    Publication date: May 18, 2006
    Inventors: Richard Essner, Farhad Daghighian, Henry Daghighian