Abstract: A blank forms a dispenser carton. The dispenser carton receives a rolled sheet to form a dispenser carton assembly. The dispenser carton has a top panel. A dispensing state of the dispenser carton the top panel includes a pair of locking tabs with notches received by a pair of flaps of side panels of the dispenser carton. The pair of flaps each have flap notches. The flap notches provide a gap between a top panel flange and a front panel of the dispenser carton. The pair of locking tabs are received into flap apertures of the pair of flaps. A pair of triangular gaps separate a portion of a back panel of the dispenser carton from left and right side panels to bias the pair of locking tabs against stops of the pair of flaps. A bottom panel of the dispenser carton includes a bottom aperture.

Abstract: A blank forms a dispenser carton. The dispenser carton receives a rolled sheet to form a dispenser carton assembly. The dispenser carton has a top panel. A dispensing state of the dispenser carton the top panel includes a pair of locking tabs with notches received by a pair of flaps of side panels of the dispenser carton. The pair of flaps each have flap notches. The flap notches provide a gap between a top panel flange and a front panel of the dispenser carton. The pair of locking tabs are received into flap apertures of the pair of flaps. A pair of triangular gaps separate a portion of a back panel of the dispenser carton from left and right side panels to bias the pair of locking tabs against stops of the pair of flaps. A bottom panel of the dispenser carton includes a bottom aperture.

Abstract: Only limited success has been previously achieved from cancer vaccines targeting unmodified tumor-associated self-antigens and new compositions and methods are needed. Immunogenic compositions and methods of use thereof are provided according to the present disclosure which include a protein effective to stimulate immune activity against a tumor-associated self-antigen, or a variant thereof which is a tumor-associated self-antigen.

Abstract: A multiple target electronic dart gaming machine having shared electronic components. According to certain embodiments, the multiple targets are mounted on opposite sides of a game board of a target assembly that is housed in a cabinet of the gaming machine. The gaming machine may be floor-standing or wall mountable. Either affixed above the top of the target assembly, below the bottom of the target assembly, or both, is a visual display video monitor for providing players and observers with game scores and the like. The game board may be axially rotated between at least first and second positions so as to allow game play on the different targets. Additionally, the position of the game board may be detected through the use of a detector on or in the board.

Abstract: The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.

Abstract: The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.

Abstract: A multiple target electronic dart gaming machine having shared electronic components. According to certain embodiments, the multiple targets are mounted on opposite sides of a game board of a target assembly that is housed in a cabinet of the gaming machine. The gaming machine may be floor-standing or wall mountable. Either affixed above the top of the target assembly, below the bottom of the target assembly, or both, is a visual display video monitor for providing players and observers with game scores and the like. The game board may be axially rotated between at least first and second positions so as to allow game play on the different targets. Additionally, the position of the game board may be detected through the use of a detector on or in the board.

Abstract: The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.

Abstract: A virtual shuffleboard table gaming apparatus including a housing having a playing field, a game acquisition circuit, and a display. As a puck is propelled towards a puck return at the distal end of the playing field, the puck temporarily obstructs at least two beams from transmitters. Sensors that receive the transmitted beams provide information to the game acquisition circuit indicative of the time when the beams were blocked and unblocked. The duration of time the beams are block are used by a game controller to calculate the angle of travel, location, and velocity of the puck. This information is then used by the game controller to determine the travel path and resting place of a virtual puck on a virtual playing field, as well as determine whether the virtual puck rests in a scoring zone and maintain a game score.

Abstract: A method for play of a parlor entertainment unit including a remote activation assembly and an activation-sensing unit. The activation-sensing unit, which may be battery operated and housed in the entertainment unit, may be in an energy-conserving sleep mode until the activation-sensing unit receives a wake-up signal. In one embodiment, the wake-up signal may be generated by the engagement of an activation mechanism, such as a coin slide. After being awoken, the activation-sensing unit may transmit an inquiry to the remote activation assembly as to whether the associated entertainment unit has been selected for play and/or whether there is a sufficient number of credits available for play. If that entertainment unit has not been selected for play, the activation-sensing unit may return to a sleep mode. However, if sufficient play credits are available for the entertainment unit, play may commence.

Abstract: A virtual shuffleboard table gaming apparatus including a housing having a playing field, a game acquisition circuit, and a display. As a puck is propelled towards a puck return at the distal end of the playing field, the puck temporarily obstructs at least two beams from transmitters. Sensors that receive the transmitted beams provide information to the game acquisition circuit indicative of the time when the beams were blocked and unblocked. The duration of time the beams are block are used by a game controller to calculate the angle of travel, location, and velocity of the puck. This information is then used by the game controller to determine the travel path and resting place of a virtual puck on a virtual playing field, as well as determine whether the virtual puck rests in a scoring zone and maintain a game score.

Abstract: A method for play of a parlor entertainment unit including a remote activation assembly and an activation-sensing unit. The activation-sensing unit, which may be battery operated and housed in the entertainment unit, may be in an energy-conserving sleep mode until the activation-sensing unit receives a wake-up signal. In one embodiment, the wake-up signal may be generated by the engagement of an activation mechanism, such as a coin slide. After being awoken, the activation-sensing unit may transmit an inquiry to the remote activation assembly as to whether the associated entertainment unit has been selected for play and/or whether there is a sufficient number of credits available for play. If that entertainment unit has not been selected for play, the activation-sensing unit may return to a sleep mode. However, if sufficient play credits are available for the entertainment unit, play may commence.

Abstract: A method is disclosed for initiating game play on a pay-for-play parlor game, such as a pool table having a playing surface, rails, pockets, a ball holding rack that retains pool balls, and an internal activation-sensing unit. The method includes depositing a game play fee into a remote activation assembly, remotely transmitting an activation signal once the game play fee is deposited, receiving the activation signal at the internal activation-sensing unit, and providing access to the pool balls upon said receiving step. A method is also disclosed for automatically scoring a pool-based game including detecting detectable devices embedded within the pool balls.

Abstract: A method is disclosed for initiating game play on a pay-for-play parlor game, such as a pool table having a playing surface, rails, pockets, a ball holding rack that retains pool balls, and an internal activation-sensing unit. The method includes depositing a game play fee into a remote activation assembly, remotely transmitting an activation signal once the game play fee is deposited, receiving the activation signal at the internal activation-sensing unit, and providing access to the pool balls upon said receiving step. A method is also disclosed for automatically scoring a pool-based game including detecting detectable devices embedded within the pool balls.

Abstract: An electrosurgical blade having an electrically insulating coating narrowly offset from the cutting edge and an optional porous polymeric coating on the cutting edge. The electrosurgical blade exhibits a bimodal temperature profile transversely across the blade, i.e., the blade is relatively hotter at the cutting edges as compared to the sides of the blade.

Abstract: A dielectric coating for electrosurgical instruments including a ceramic coating applied to the instrument and a parylene coating applied to the ceramic coating. The coating may be used on monopolar and bipolar electrosurgical instruments to provide insulation having good dielectric properties.

Abstract: A testing device for detecting defects in insulation of electrosurgical instruments that includes an implement or wand having a distal end, an electrode for generating a spark adapted to detect a defect in the insulation, and mounting means for removably mounting the electrode to the distal end of the implement. The removable mounting means includes a shank that is received in a socket or bore defined in the distal end of the wand and is engageable with the wand within the socket so the shank can easily be removed from the socket after use. The wand is releasably engageable with the housing by a flexible bracket that extends from the housing. The device may include a pad having a reflective top surface with ridges upon which the surgical instrument to be tested is placed.