Patents by Inventor Richard Ferrero

Richard Ferrero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of interaction between Nod1 and Gram-negative bacteria by Nod1 response to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island (cagPAI)
    Publication number: 20060084090
    Abstract: A method for identifying a compound that modulates the interaction between Nod1 and a Gram-negative bacteria comprising contacting a Nod1 expressing cell with a cagPAI-positive H. pylori in the presence of a compound, contacting a Nod1 expressing cell with a cagPAI-positive H. pylori in the absence of said compound, and detecting the activation of a pro-inflammatory factor and/or the production of a pro-inflammatory cytokine or chemokine, wherein altered activation and/or production indicates that said compound modulates the interaction between Nod1 and the Gram-negative bacteria. The method is useful for identifying compounds for regulating the signaling cascade involving Nod1 against Gram-negative bacteria that cause mucosal inflammation in animal hosts.
    Type: Application
    Filed: August 3, 2005
    Publication date: April 20, 2006
    Inventors: Richard Ferrero, Dana Philpott, Jerome Viala, Ivo Boneca, Catherine Chaput, Stephen Girardin
  • Genes of Heliciobacter pylori necessary for the regulation and maturation of urease and their use
    Patent number: 6271017
    Abstract: Oligonucletodie sequences are disclosed specific to H. pylori urease and useful as DNA probes and primers in the detection of H. pylori infection in humans.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 7, 2001
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Agnès Labigne, Valérie Cussac, Richard Ferrero
  • Genes of Helicobacter pylori necessary for the regulation and maturation of urease and their use
    Patent number: 6027878
    Abstract: Oligonucleotide sequences are disclosed specific to H. pylori urease and useful as DNA probes and primers in the detection of H. pylori infection in humans. Also disclosed are methods of hybridization and amplification using these sequences.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 22, 2000
    Assignees: Institut Pasteur, Inistitut National de la Sante et de la Recherche Medicale
    Inventors: Agnes Labigne, Valerie Cussac, Richard Ferrero
  • Genes of Helicobacter pylori necessary for the regulation and maturation of urease and their use
    Patent number: 5986051
    Abstract: This invention relates to Helicobacter polypeptides, particularly UreE, UreF, UreG, UreH, and UreI, immunogenic fragments of those polypeptides, and compositions containing those polypeptides or fragments. This invention also relates to purified antibodies that bind to the polypeptides of this invention and to compositions comprising those antibodies.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: November 16, 1999
    Assignees: Institut Pasteur, Institut National de la Santa et de la Recherche Medicale
    Inventors: Agnes Labigne, Valerie Cussac, Richard Ferrero