Patents by Inventor Richard G. HIBBERT

Richard G. HIBBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION THERAPY
    Publication number: 20250002600
    Abstract: The present invention provides combination therapy using a binding agent that binds to human CD137 and to human PD-L1 in combination with a PD-1 inhibitor to reduce or prevent progression of a tumor or treating cancer.
    Type: Application
    Filed: October 5, 2022
    Publication date: January 2, 2025
    Inventors: Alexander MUIK, Kristina SCHÖDEL, Nora PENCHEVA, Maria N. JURE-KUNKEL, Ugur SAHIN, Sina FELLERMEIER-KOPF, Patricia GARRIDO CASTRO, Jordan BLUM, Friederike GIESEKE, Esther C. W. BREIJ, Lars GUELEN, Joost NEIJSSEN, Karsten BECKMANN, Claudia PAULMANN, Bart-Jan DE KREUK, Richard G. HIBBERT, Janine SCHUURMAN, Aran LABRIJN, Ivan KUZMANOV
  • HIGHLY PURIFIED EPCORITAMAB COMPOSITIONS
    Publication number: 20240400685
    Abstract: The present disclosure provides highly purified epcoritamab compositions, which comprise a bispecific antibody that binds CD3 and CD20. In the highly purified compositions, impurities, such as epcoritamab protein variants, process-related impurities and/or product-related impurities, have been minimized or removed. Methods of preparing the highly purified epcoritamab compositions are also provided.
    Type: Application
    Filed: May 15, 2024
    Publication date: December 5, 2024
    Inventors: Richard G. HIBBERT, Bolette BJERREGAARD, Søren S. JENSEN, César Filipe OLIVEIRA DA COSTA, Rohan O'DONNELL
  • METHODS FOR THE QUANTIFICATION OF GLYCOPROTEINS
    Publication number: 20230089196
    Abstract: The invention relates to methods for the quantification of glycoproteins in a sample, comprising quantifying said glycoproteins by comparison with an internal standard, wherein said internal standard comprises variant forms of said glycoproteins, wherein said variant forms contain only core Asn-linked GlcNAc moieties.
    Type: Application
    Filed: February 19, 2021
    Publication date: March 23, 2023
    Inventors: Ewald T.J. VAN DEN BREMER, Sipke SANGERS, Demelza WILLEMSZ, Richard G. HIBBERT, Rob N. DE JONG, Søren Skov JENSEN, Emil POULSEN
  • BISPECIFIC AND MULTISPECIFIC ANTIBODIES AND METHOD FOR ISOLATION OF SUCH
    Publication number: 20180201693
    Abstract: Bispecific and multispecific antibodies having differentially modified light chains, that allows for isolation of the bispecific or multispecific antibodies based on a differential affinity towards an affinity reagent.
    Type: Application
    Filed: July 1, 2016
    Publication date: July 19, 2018
    Inventors: Richard G. HIBBERT, Aran F. LABRIJN, Arnout F. GERRITSEN, Janine SCHUURMAN, Paul PARREN