Patents by Inventor Richard G. Wax

Richard G. Wax has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cultures for production of avermectin aglycones
    Patent number: 5583029
    Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: December 10, 1996
    Assignee: Pfizer Inc.
    Inventors: Lapyuen H. Lam, Hamish A. I. McArthur, Richard G. Wax
  • Process for production of avermectin aglycones and cultures therefor
    Patent number: 5576200
    Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: November 19, 1996
    Assignee: Pfizer Inc.
    Inventors: Lapyuen Lam, Hamish A. I. McArthur, Richard G. Wax
  • Cultures for production of avermectin aglycones
    Patent number: 5240850
    Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
    Type: Grant
    Filed: February 26, 1991
    Date of Patent: August 31, 1993
    Assignee: Pfizer Inc.
    Inventors: Lapyuen H. Lam, Hamish A. I. McArthur, Richard G. Wax
  • Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans
    Patent number: 4065356
    Abstract: An antibiotic, designated FR-02A or efrotomycin, is obtained by culturing Streptomyces lactamdurans in a fermentation broth and extracting the whole broth with a water immiscible polar organic solvent to obtain the antibiotic FR-02A.
    Type: Grant
    Filed: March 1, 1977
    Date of Patent: December 27, 1977
    Assignee: Merck & Co., Inc.
    Inventors: William M. Maiese, Richard G. Wax
  • Antibiotic FR-02A and therapeutic compositions thereof
    Patent number: 4024251
    Abstract: This invention relates to a new antibiotic agent which also possesses growth promoting activity. The antibiotic is isolated from the fermentation broth of Streptomyces lactamdurans by solvent extraction and designated Efrotomycin.
    Type: Grant
    Filed: February 12, 1976
    Date of Patent: May 17, 1977
    Assignee: Merck & Co., Inc.
    Inventors: William M. Maiese, Richard G. Wax