Abstract: A method for storing object state on hash chains. A read request that includes a received field name is received by an object with a plurality of fields. A field value that corresponds to the received field name is retrieved from a hash chain of the object by traversing the hash chain. A block is found that includes the field value from the plurality of field values that corresponds to the received field name. A response to the read request that includes the field value is generated and transmitted.

Abstract: An invisible light sensing device senses invisible light from a plurality of invisible light emitting or reflecting objects in which each of the invisible light emitting or reflecting objects emits or reflects invisible light in an identification pattern that is distinct from other identification patterns. An identification pattern is based on a sequenced pulsing pattern of invisible light that is emitted by an invisible light emitting object to form the identification pattern. An identification pattern is also based on an invisible light reflective coating that is applied to an invisible light reflecting object.

Abstract: A method for message management is disclosed. The method includes: deriving, by a first subscriber node (SN), a secret value associated with a publisher node (PN); generating, by the first SN, a first expected sequence number using a one-way function and the secret value; receiving, by the first SN, a first publisher message generated by the PN and including a first sequence number; validating, by the first SN, the first publisher message by comparing the first sequence number with the first expected sequence number; processing, by the first SN, a payload of the first publisher message in response to the first sequence number and the first expected sequence number matching; and generating, by the first SN node, a second expected sequence number using the one-way function, the first sequence number, and the secret value.

Abstract: An invisible light sensing device senses invisible light from a plurality of invisible light emitting objects in which each of the invisible light emitting objects emits invisible light in an identification pattern that is distinct from other identification patterns. An identification pattern is based on one or more apertures through which invisible light is emitted to form the identification pattern. An identification pattern is also based on a plurality of invisible light emitters in which at least a portion of the invisible light emitters are positioned and activated to form the identification pattern.

Abstract: A method for message management is disclosed. The method includes: deriving, by a first subscriber node (SN), a secret value associated with a publisher node (PN); generating, by the first SN, a first expected sequence number using a one-way function and the secret value; receiving, by the first SN, a first publisher message generated by the PN and including a first sequence number; validating, by the first SN, the first publisher message by comparing the first sequence number with the first expected sequence number; processing, by the first SN, a payload of the first publisher message in response to the first sequence number and the first expected sequence number matching; and generating, by the first SN node, a second expected sequence number using the one-way function, the first sequence number, and the secret value.

Abstract: The present invention relates to a method for determining the in vivo localization of double-strand breaks in a host cell, comprising incubating a host cell suspected to comprise DNA double-strand breaks and a linear polynucleotide comprising a known sequence, detecting the in vivo insertion sites of said polynucleotide in the genome of said host cell, and assessing the in vivo localization of double-strand breaks. Further envisaged by the present invention is a method for obtaining an endonuclease with altered in vivo specificity. Finally, the present invention is directed to a kit for determining in vivo specificity of an endonuclease.

Abstract: The present invention relates to a method for determining the in vivo localization of double-strand breaks in a host cell, comprising incubating a host cell suspected to comprise DNA double-strand breaks and a linear polynucleotide comprising a known sequence, detecting the in vivo insertion sites of said polynucleotide in the genome of said host cell, and assessing the in vivo localization of double-strand breaks. Further envisaged by the present invention is a method for obtaining an endonuclease with altered in vivo specificity. Finally, the present invention is directed to a kit for determining in vivo specificity of an endonuclease.

Abstract: Systems and methods for identifying and tracking individuals and samples are disclosed. The system includes a sample container, an individual's identification sample portion coupled to the sample container and means for identifying the individual's identification sample portion. The individual's identification sample portion may be configured to accept fingerprints, human iris scan, human eye color, facial recognition photo and/or DNA. A method is disclosed for using the system for identifying and tracking a sample from an individual. The method includes placing the sample from the individual in a sample container, obtaining and placing an individual's identification sample on an individual's identification sample portion coupled to the sample container, and identifying the individual's identification sample using appropriate instruments to identify the sample.

Abstract: An animal isolation and caging system which maximizes cage density within a ventilated rack is provided. The rack includes at least one air exhaust plenum, and at least one canopy disposed within the rack for ventilation of the cages housed in a rack system. The rack is capable of supporting a first cage within the rack below a first canopy, and also positioning a second cage below a second canopy. The filter top of the first cage provided by the invention also provides a filter retainer having a filter top retainer wall designed to be in contact with a first canopy unit forming an enclosed space so configured as to create an enclosed space from which the animal isolation and caging system of the invention creates a zone of negative pressure so as to permit air to be drawn into an air exhaust plenum or duct from the interior of the first cage through the top of the first cage.

Abstract: An animal isolation and caging system which maximizes cage density within a ventilated rack is provided. The rack includes at least one air exhaust plenum, and at least one canopy disposed within the rack for ventilation of the cages housed in a rack system. The rack is capable of supporting a first cage within the rack below a first canopy, and also positioning a second cage below a second canopy. The filter top of the first cage provided by the invention also provides a filter retainer having a filter top retainer wall designed to be in contact with a first canopy unit forming an enclosed space so configured as to create an enclosed space from which the animal isolation and caging system of the invention creates a zone of negative pressure so as to permit air to be drawn into an air exhaust plenum or duct from the interior of the first cage through the top of the first cage.

Abstract: An animal isolation and caging system which maximizes cage density within a ventilated rack is provided. The rack includes at least one air exhaust plenum, and at least one canopy disposed within the rack for ventilation of the cages housed in a rack system. The rack is capable of supporting a first cage within the rack below a first canopy, and also positioning a second cage below a second canopy. The filter top of the first cage provided by the invention also provides a filter retainer having a filter top retainer wall designed to be in contact with a first canopy unit forming an enclosed space so configured as to create an enclosed space from which the animal isolation and caging system of the invention creates a zone of negative pressure so as to permit air to be drawn into an air exhaust plenum or duct from the interior of the first cage through the top of the first cage.

Abstract: The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized.The method includes contacting a nitromethyl amino acid compound with at least one reducing agent to form the 1,3-diamino-3-substituted-2-propanol chemical intermediate.

Abstract: The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized.This method includes contacting a nitromethyl amino acid compound with at least one reducing agent to form the 1,3-diamino-3-substituted-2-propanol chemical intermediate.