Patents by Inventor Richard Gelberman

Richard Gelberman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer nanofiber scaffold for a heparin/fibrin based growth factor delivery system
    Patent number: 9375516
    Abstract: A growth factor delivery scaffold combines a heparin/fibrin-based delivery system (HBDS) with a backbone based on polymer nanofibers for tissue (e.g., tendon and ligament) repair. The scaffold has improved surgical handling properties compared to the gelatinous consistency of the prior art HBDS system and retains the capability for delivering mesenchymal cells and controlling the release of growth factors. One application for the scaffold is mesenchymal stem cell (MSC) therapy for flexor tendon repair. The scaffold can deliver growth factors in a sustained manner, can be implanted for flexor tendon repair, is biocompatible, and is not cytotoxic. The growth factor delivery scaffold may also be used in the surgical repair of an injury to bone, muscle, cartilage, or other tissues.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: June 28, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Stavros Thomopoulos, Shelly Sakiyama-Elbert, Matthew Silva, Richard Gelberman, Younan Xia, Andrea Schwartz, Jingwei Xie
  • POLYMER NANOFIBER SCAFFOLD FOR A HEPARIN / FIBRIN BASED GROWTH FACTOR DELIVERY SYSTEM
    Publication number: 20140135945
    Abstract: A growth factor delivery scaffold combines a heparin/fibrin-based delivery system (HBDS) with a backbone based on polymer nanofibers for tissue (e.g., tendon and ligament) repair. The scaffold has improved surgical handling properties compared to the gelatinous consistency of the prior art HBDS system and retains the capability for delivering mesenchymal cells and controlling the release of growth factors. One application for the scaffold is mesenchymal stem cell (MSC) therapy for flexor tendon repair. The scaffold can deliver growth factors in a sustained manner, can be implanted for flexor tendon repair, is biocompatible, and is not cytotoxic. The growth factor delivery scaffold may also be used in the surgical repair of an injury to bone, muscle, cartilage, or other tissues.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Inventors: Stavros Thomopoulos, Shelly Sakiyama-Elbert, Matthew Silva, Richard Gelberman, Younan Xia, Andrea Schwartz, Jingwei Xie
  • Polymer nanofiber scaffold for a heparin / fibrin based growth factor delivery system
    Patent number: 8673323
    Abstract: A growth factor delivery scaffold combines a heparin/fibrin-based delivery system (HBDS) with a backbone based on polymer nanofibers for tissue (e.g., tendon and ligament) repair. The scaffold has improved surgical handling properties compared to the gelatinous consistency of the prior art HBDS system and retains the capability for delivering mesenchymal cells and controlling the release of growth factors. One application for the scaffold is mesenchymal stem cell (MSC) therapy for flexor tendon repair. The scaffold can deliver growth factors in a sustained manner, can be implanted for flexor tendon repair, is biocompatible, and is not cytotoxic. The growth factor delivery scaffold may also be used in the surgical repair of an injury to bone, muscle, cartilage, or other tissues.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: March 18, 2014
    Assignee: Washington University
    Inventors: Stavros Thomopoulos, Shelly Sakiyama-Elbert, Matthew Silva, Richard Gelberman, Younan Xia, Andrea Schwartz, Jingwei Xie
  • POLYMER NANOFIBER SCAFFOLD FOR A HEPARIN / FIBRIN BASED GROWTH FACTOR DELIVERY SYSTEM
    Publication number: 20130004541
    Abstract: A growth factor delivery scaffold combines a heparin/fibrin-based delivery system (HBDS) with a backbone based on polymer nanofibers for tissue (e.g., tendon and ligament) repair. The scaffold has improved surgical handling properties compared to the gelatinous consistency of the prior art HBDS system and retains the capability for delivering mesenchymal cells and controlling the release of growth factors. One application for the scaffold is mesenchymal stem cell (MSC) therapy for flexor tendon repair. The scaffold can deliver growth factors in a sustained manner, can be implanted for flexor tendon repair, is biocompatible, and is not cytotoxic. The growth factor delivery scaffold may also be used in the surgical repair of an injury to bone, muscle, cartilage, or other tissues.
    Type: Application
    Filed: January 5, 2012
    Publication date: January 3, 2013
    Applicant: WASHINGTON UNIVERSITY IN ST. LOUIS
    Inventors: Stavros Thomopoulos, Shelly Sakiyama-Elbert, Matthew Silva, Richard Gelberman, Younan Xia, Andrea Schwartz, Jingwei Xie