Patents by Inventor Richard Gless

Richard Gless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conformationally restricted urea inhibitors of soluble epoxide hydrolase
    Patent number: 9029550
    Abstract: Inhibitors of the soluble epoxide exemplary hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: May 12, 2015
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Paul D. Jones, Christophe Morisseau, Huazhang Huang, Hsing-Ju Tsai, Richard Gless, Jr.
  • CONFORMATIONALLY RESTRICTED UREA INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE
    Publication number: 20130274476
    Abstract: Inhibitors of the soluble epoxide exemplary hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Application
    Filed: June 14, 2013
    Publication date: October 17, 2013
    Inventors: Bruce D. Hammock, Paul D. Jones, Christophe Morisseau, Huazhang Huang, Hsing-Ju Tsai, Richard Gless, JR.
  • Conformationally restricted urea inhibitors of soluble epoxide hydrolase
    Patent number: 8501783
    Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: August 6, 2013
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Paul D. Jones, Christophe Morisseau, Huazhang Huang, Hsing-Ju Tsai, Richard Gless, Jr.
  • CONFORMATIONALLY RESTRICTED UREA INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE
    Publication number: 20130137726
    Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Application
    Filed: April 25, 2012
    Publication date: May 30, 2013
    Applicant: The Regents of the University of California
    Inventors: Bruce D. Hammock, Paul D. Jones, Christophe Morisseau, Huazhang Huang, Hsing-Ju Tsai, Richard Gless, JR.
  • Conformationally restricted urea inhibitors of soluble epoxide hydrolase
    Patent number: 8188289
    Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: May 29, 2012
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Paul D. Jones, Christophe Morisseau, Huazhang Huang, Hsing-Ju Tsai, Richard Gless
  • Compositions and Their Use as Anti-Tumor Agents
    Publication number: 20120071513
    Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.
    Type: Application
    Filed: November 28, 2011
    Publication date: March 22, 2012
    Applicant: COMPASS PHARMACEUTICALS LLC
    Inventors: David Kanne, John Ward, Gary Look, X. Michael Wang, Diva Chan, Tina Lee, Donald R. James, Richard Gless, John Schullek, Charles Vacin
  • Compositions and Their Use as Anti-Tumor Agents
    Publication number: 20110178087
    Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.
    Type: Application
    Filed: March 30, 2011
    Publication date: July 21, 2011
    Applicant: Compass Pharmaceuticals LLC.
    Inventors: David Kanne, John Ward, Gary Look, X. Michael Wang, Diva Chan, Tina Lee, Donald R. James, Richard Gless, John Schullek, Charles Vacin
  • Compositions and their use as anti-tumor agents
    Publication number: 20090018145
    Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreating carcinomas) and mesotheliomas.
    Type: Application
    Filed: October 18, 2005
    Publication date: January 15, 2009
    Applicant: Compass Pharmaceuticals LLC
    Inventors: David Kanne, John Ward, Gary Look, X. Michael Wang, Diva Chan, Tina Lee, Donald R. James, Richard Gless, John Schullek, Charles Vacin
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20080076770
    Abstract: Disclosed are urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, and diabetes related diseases.
    Type: Application
    Filed: September 25, 2007
    Publication date: March 27, 2008
    Inventor: Richard Gless
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20080032978
    Abstract: Disclosed are urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, and diabetes-related diseases.
    Type: Application
    Filed: July 30, 2007
    Publication date: February 7, 2008
    Inventor: Richard Gless
  • CONFORMATIONALLY RESTRICTED UREA INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE
    Publication number: 20070225283
    Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
    Type: Application
    Filed: March 13, 2007
    Publication date: September 27, 2007
    Applicants: The Regents of the University of California, Arete Therapeutics
    Inventors: Bruce Hammock, Paul Jones, Christophe Morisseau, Huazhang Huang, Hsing-Ju Tsai, Richard Gless