Abstract: In one aspect the present disclosure refers to a supplementary device for a manually operable injection device, the supplementary device comprising: a body attachable to an elongated housing of the injection device, at least one connector connected to the body and connectable to the housing, wherein the body is attachable to the housing via the at least one connector, a sensor arrangement coupled to at least one of the body and the at least one connector and configured to measure a longitudinal force component acting between the at least one connector and the body in a direction parallel to the elongation of the housing.

Abstract: Disclosed herein is an instrument that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface such as a patient having burn injuries. In handheld embodiments of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printer head and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. A soft deformable roller mitigates further damage to the injured area of skin as it rolls over it and a gimbal mechanism to which the printer head is attached is in contact with the injured tissue but is configured so that the printer head while in contact with tissue, does not exert undue pressure on the would area.

Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.

Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.

Abstract: The present disclosure relates in one aspect to a measuring arrangement for measuring a volume occupied by a liquid medium inside a liquid reservoir, the measuring arrangement including a container having an interior volume containing a gas reservoir filled with a gaseous medium and containing a liquid reservoir filled with a liquid medium, wherein the gas reservoir and the liquid reservoir are hermetically separated by an impenetrable separation wall, a volume modulator to induce a volume change of the gas reservoir, a pressure sensor arranged inside the gas reservoir to measure a pressure change of the gaseous medium in response to the volume change of the gas reservoir, and a controller connectable to the pressure sensor, wherein the controller is configured to calculate the volume of the liquid reservoir on the basis of the pressure change and the volume change.

Abstract: A first aspect of the invention is an agricultural composition comprising nanoparticles, an agrochemical active ingredient in the nanoparticles, and optionally (but in some embodiments preferably) a carrier for the nanoparticles. In some embodiments, the nanoparticles are viral particles or capsids, particularly plant viral particles or capsids. In some embodiments, the carrier comprises an inert or biodegradable carrier (e.g., a solid carrier) to which the nanoparticles are bound or in which the nanoparticles are suspended. In some embodiments, the carrier comprises inert or biodegradable polymer fibers.

Abstract: In one aspect the present disclosure refers to a measuring arrangement for measuring of a volume change of a liquid medium located inside a liquid reservoir, the measuring arrangement comprising: a gas tight enclosure having an interior volume containing a gas reservoir and containing the liquid reservoir, wherein the liquid reservoir is filled with a liquid medium, a gas inlet in flow connection with the gas reservoir and extending through a boundary of the gas tight enclosure to an exterior of the gas tight enclosure, an outlet connectable with the liquid reservoir and extending through the boundary of the gas tight enclosure, wherein the gas reservoir and the liquid reservoir are hermetically separated by an impenetrable separation wall, and a flow meter arranged in or across the gas inlet to measure an ingress of a gaseous medium through the inlet in response to a withdrawal of the liquid medium from the liquid reservoir through the outlet.

Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.

Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.

Abstract: In one aspect the present disclosure refers to a measuring arrangement for measuring of a volume change of a liquid medium located inside a liquid reservoir, the measuring arrangement comprising: a gas tight enclosure having an interior volume containing a gas reservoir and containing the liquid reservoir, wherein the liquid reservoir is filled with a liquid medium, a gas inlet in flow connection with the gas reservoir and extending through a boundary of the gas tight enclosure to an exterior of the gas tight enclosure, an outlet connectable with the liquid reservoir and extending through the boundary of the gas tight enclosure, wherein the gas reservoir and the liquid reservoir are hermetically separated by an impenetrable separation wall, and a flow meter arranged in or across the gas inlet to measure an ingress of a gaseous medium through the inlet in response to a withdrawal of the liquid medium from the liquid reservoir through the outlet.

Abstract: The present disclosure relates in one aspect to a measuring arrangement for measuring a volume occupied by a liquid medium inside a liquid reservoir, the measuring arrangement including a container having an interior volume containing a gas reservoir filled with a gaseous medium and containing a liquid reservoir filled with a liquid medium, wherein the gas reservoir and the liquid reservoir are hermetically separated by an impenetrable separation wall, a volume modulator to induce a volume change of the gas reservoir, a pressure sensor arranged inside the gas reservoir to measure a pressure change of the gaseous medium in response to the volume change of the gas reservoir, and a controller connectable to the pressure sensor, wherein the controller is configured to calculate the volume of the liquid reservoir on the basis of the pressure change and the volume change.

Abstract: In one aspect the present disclosure refers to a supplementary device (10) for a manually operable injection device (1), the supplementary device comprising: —a body (11) attachable to an elongated housing (2) of the injection device (1), —at least one connector (12, 14) connected to the body (11) and connectable to the housing (2), wherein the body (11) is attachable to the housing (2) via the at least one connector (12, 14), —a sensor arrangement (20) coupled to at least one of the body (11) and the at least one connector (12, 14) and configured to measure a longitudinal force component (F) acting between the at least one connector (12, 14) and the body (11) in a direction parallel to the elongation of the housing (2).

Abstract: The invention relates to a linear actor arrangement, comprising a linear actor with two ends whose distance is variable depending on an energizing of the linear actor, wherein each end is attached to a respective first or second coupling element which engage a coupling surface, wherein the coupling surface and the coupling elements exhibit mating surface structures in such a manner that the coupling elements are prevented from moving in a direction while being allowed to move in an opposite direction.

Abstract: An arrangement for determining a position (x) of a stopper relative to a container in a drug delivery device includes an acoustic source configured to emit an acoustic signal and an acoustic sensor configured to detect an acoustic signal, a processing unit for controlling the acoustic source and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper. A method for determining a position (x) of a stopper relative to a container in a drug delivery device includes the steps of emitting an acoustic signal from an acoustic source, detecting an acoustic signal caused by the emitted acoustic signal by means of an acoustic sensor, and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper by means of a processing unit.

Abstract: The invention relates to a drug delivery device, comprising a control unit, a drive unit, a pressurizing medium container arranged to contain a pressurizing liquid, a drug container arranged to contain a drug and a discharge nozzle, wherein the drive unit when controlled and energized by the control unit is arranged to generate a pressure gradient in the pressurizing liquid thereby propagating the pressure to the drug container and at least partially displacing the drug from the drug container through the discharge nozzle, wherein the drive unit is arranged as an electro-osmotic actor.

Abstract: A first aspect of the invention is an agricultural composition comprising nanoparticles, an agrochemical active ingredient in the nanoparticles, and optionally (but in some embodiments preferably) a carrier for the nanoparticles. In some embodiments, the nanoparticles are viral particles or capsids, particularly plant viral particles or capsids. In some embodiments, the carrier comprises an inert or biodegradable carrier (e.g., a solid carrier) to which the nanoparticles are bound or in which the nanoparticles are suspended. In some embodiments, the carrier comprises inert or biodegradable polymer fibers.

Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.

Abstract: The invention relates to a stopper arrangement for a drug delivery device, comprising a stopper, a linear actor coupled with one end to the stopper and with an opposite end to a coupling arrangement, wherein the stopper arrangement is configured to be disposed within a container of a drug delivery device, wherein a shape and/or material of the stopper and the coupling arrangement are configured such that a first frictional force between the coupling arrangement and the container is lower than a frictional force between the stopper and the container when the linear actor is contracting and that second frictional force between the coupling arrangement and the container is greater than the frictional force between the stopper and the container when the linear actor is expanding.

Abstract: The invention relates to an arrangement for determining a position (x) of a stopper relative to a container in a drug delivery device, comprising an acoustic source configured to emit an acoustic signal and an acoustic sensor configured to detect an acoustic signal, a processing unit for controlling the acoustic source and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper. Furthermore, the invention relates to a method for determining a position (x) of a stopper relative to a container in a drug delivery device, the method comprising the steps of emitting an acoustic signal from an acoustic source, detecting an acoustic signal caused by the emitted acoustic signal by means of an acoustic sensor, and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper by means of a processing unit.

Abstract: The invention relates to an arrangement for determining a position (x) of a stopper relative to a container in a drug delivery device, comprising an acoustic source configured to emit an acoustic signal and an acoustic sensor configured to detect an acoustic signal, a processing unit for controlling the acoustic source and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper. Furthermore, the invention relates to a method for determining a position (x) of a stopper relative to a container in a drug delivery device, the method comprising the steps of emitting an acoustic signal from an acoustic source, detecting an acoustic signal caused by the emitted acoustic signal by means of an acoustic sensor, and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper by means of a processing unit.