Patents by Inventor Richard H. Guy

Richard H. Guy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ultrasound-enhanced sampling of materials through the skin
    Patent number: 5636632
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultra sound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: March 9, 1994
    Date of Patent: June 10, 1997
    Assignees: Cygnus, Inc., The Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn
  • Ultrasound-enhanced delivery of materials into and through the skin
    Patent number: 5323769
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: June 28, 1994
    Assignees: Cygnus Therapeutic Systems, The Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn
  • Device for iontophoretic non-invasive sampling or delivery of substances
    Patent number: 5279543
    Abstract: The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises:(a) a positive electrode;(b) a negative electrode, and(c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample.The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal.
    Type: Grant
    Filed: April 30, 1992
    Date of Patent: January 18, 1994
    Assignee: The Regents of The University of California
    Inventors: Peretz Glikfeld, Christopher Cullander, Robert S. Hinz, Richard H. Guy
  • Ultrasound-enhanced delivery of materials into and through the skin
    Patent number: 5231975
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: March 2, 1992
    Date of Patent: August 3, 1993
    Assignees: Cygnus Therapeutic Systems, Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn
  • Ultrasound-enhanced delivery of materials into and through the skin
    Patent number: 5115805
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: May 26, 1992
    Assignees: Cygnus Therapeutic Systems, The Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn