Patents by Inventor Richard H. Kramer

Richard H. Kramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240009151
    Abstract: Disclosed herein are pharmaceutical compositions comprising an azobenzene photoswitch compound and an alkylated cyclodextrin. Such compositions may be administered to the eye to treat a variety of retina disorders.
    Type: Application
    Filed: October 22, 2021
    Publication date: January 11, 2024
    Inventors: Richard H. KRAMER, Kevin CAO, Hovhannes GUKASYAN, Brian M. STREM
  • Publication number: 20200390731
    Abstract: Disclosed herein, inter alia, are compositions and methods for modulating the retinoic acid receptor signaling pathway and treating vision degeneration.
    Type: Application
    Filed: November 16, 2018
    Publication date: December 17, 2020
    Inventors: Richard H. Kramer, Michel Telias, Bristol Layne Denlinger, Zachary John Helft
  • Patent number: 9688617
    Abstract: The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: June 27, 2017
    Assignee: The Regents of the University of California
    Inventors: Dirk Trauner, Ehud Y. Isacoff, Richard H. Kramer, Matthew R. Banghart, Doris L. Fortin, Alexandre Mourot
  • Patent number: 9629911
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: April 25, 2017
    Assignee: The Regents of the University of California
    Inventors: Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Patent number: 9428926
    Abstract: A prefabricated building includes a sheet folded to form a structural member defining an interior space. The structural member defines an upper guide hole that extends from the interior space of the structural member to the exterior of the structural member, and a lower guide hole that extends from the interior space of the structural member to the exterior of the structural member. The prefabricated building also includes a guide member that is fixed relative to a foundation. The structural member is aligned so that the guide member passes through the upper guide hole and the lower guide hole.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: August 30, 2016
    Inventor: Richard H. Kramer
  • Publication number: 20160229794
    Abstract: The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
    Type: Application
    Filed: April 19, 2016
    Publication date: August 11, 2016
    Inventors: Dirk Trauner, Ehud Y. Isacoff, Richard H. Kramer, Matthew R. Banghart, Doris L. Fortin, Alexandre Mourot
  • Patent number: 9334231
    Abstract: The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: May 10, 2016
    Assignee: The Regents of the University of California
    Inventors: Dirk Trauner, Ehud Y. Isacoff, Richard H. Kramer, Matthew R. Banghart, Doris L. Fortin, Alexandre Mourot
  • Publication number: 20150224193
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Application
    Filed: January 8, 2015
    Publication date: August 13, 2015
    Inventors: Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Patent number: 9097707
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: August 4, 2015
    Assignee: The Regents of the University of California
    Inventors: Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Publication number: 20150158811
    Abstract: The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 11, 2015
    Inventors: Dirk Trauner, Ehud Y. Isacoff, Richard H. Kramer, Matthew R. Banghart, Doris L. Fortin, Alexandre Mourot
  • Patent number: 8993736
    Abstract: The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: March 31, 2015
    Assignee: The Regents of the University of California
    Inventors: Dirk Trauner, Ehud Y. Isacoff, Richard H. Kramer, Matthew R. Banghart, Doris L. Fortin, Alexandre Mourot
  • Publication number: 20130118092
    Abstract: A prefabricated building includes a sheet folded to form a structural member defining an interior space. The structural member defines an upper guide hole that extends from the interior space of the structural member to the exterior of the structural member, and a lower guide hole that extends from the interior space of the structural member to the exterior of the structural member. The prefabricated building also includes a guide member that is fixed relative to a foundation. The structural member is aligned so that the guide member passes through the upper guide hole and the lower guide hole.
    Type: Application
    Filed: July 19, 2011
    Publication date: May 16, 2013
    Inventor: Richard H. Kramer
  • Patent number: 8309350
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Grant
    Filed: February 1, 2012
    Date of Patent: November 13, 2012
    Assignee: The Regents of the University of California
    Inventors: Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Publication number: 20120190094
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Application
    Filed: February 1, 2012
    Publication date: July 26, 2012
    Inventors: EHUD Y. ISACOFF, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Patent number: 8114843
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: February 14, 2012
    Assignee: The Regents of the University of California
    Inventors: Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Publication number: 20110207213
    Abstract: The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
    Type: Application
    Filed: October 29, 2009
    Publication date: August 25, 2011
    Inventors: Dirk Trauner, Ehud Y. Isacoff, Richard H. Kramer, Matthew R. Banghart, Doris L. Fortin, Alexandre Mourot
  • Patent number: 6837263
    Abstract: A liquid level control system including a tank; a source of liquid in communication with the tank; a pressure fluid actuated valve for controlling the flow of liquid to the tank from the source; a pressure sensor disposed in the tank to monitor the hydrostatic pressure determined by the quantity of liquid in the tank. A source of pressure fluid is provided which is normally vented to the atmosphere. A pressure fluid amplifier is coupled to the pressure fluid actuated valve and to the source of pressure fluid. When the pressure sensor sensed an increase of pressure caused by an increase in the liquid level in the tank, the pressure fluid amplifier is effective to actuate the valve to close and militate against flowing into the tank to maintain the liquid at a predetermined level.
    Type: Grant
    Filed: October 20, 2001
    Date of Patent: January 4, 2005
    Assignee: DistaView Corporation
    Inventor: Richard H. Kramer
  • Publication number: 20020078995
    Abstract: A liquid level control system including a tank; a source of liquid in communication with the tank; a pressure fluid actuated valve for controlling the flow of liquid to the tank from the source; a pressure sensor disposed in the tank to monitor the hydrostatic pressure determined by the quantity of liquid in the tank. A source of pressure fluid is provided which is normally vented to the atmosphere. A pressure fluid amplifier is coupled to the pressure fluid actuated valve and to the source of pressure fluid. When the pressure sensor sensed an increase of pressure caused by an increase in the liquid level in the tank, the pressure fluid amplifier is effective to actuate the valve to close and militate against flowing into the tank to maintain the liquid at a predetermined level.
    Type: Application
    Filed: October 20, 2001
    Publication date: June 27, 2002
    Inventor: Richard H. Kramer
  • Patent number: 5545958
    Abstract: A merchandising system for holding items, such as compact discs, is disclosed. The system includes a base on which several item holders are rotatably mounted. Each item holder is configured to receive at least one and preferably a plurality of items arranged vertically. A plurality of motors rotate the items while cooperating sensors provide an output corresponding to the rotational position of the item holder. A controller is coupled between the sensors and motors to maintain alignment of rotation based on the output signals received from the sensors.
    Type: Grant
    Filed: October 13, 1994
    Date of Patent: August 13, 1996
    Assignee: KCS Industries, Inc.
    Inventor: Richard H. Kramer