Patents by Inventor Richard H. Peters

Richard H. Peters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NORPREGNANE DERIVATIVES FOR THE RISK REDUCTION OF BREAST CANCER
    Publication number: 20170157143
    Abstract: In one embodiment, the application discloses a method for the prophylaxis or the treatment of a pre-cancerous lesion, including atypical intraductal breast hyperplasia, in a subject, wherein the method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising compound of the formula I.
    Type: Application
    Filed: December 1, 2016
    Publication date: June 8, 2017
    Applicant: Helix Twelve Pharmaceuticals Corporation, Inc.
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Fred Schaufele
  • Polyamide/polyphenylene ether fibers and fiber-forming method
    Patent number: 9090999
    Abstract: A fiber is prepared by melt extruding a composition including specific amounts of a polyamide and a polyphenylene ether along with a compatabilizer. Particular combinations produce fibers having a desirable combination of good tenacity and low denier per fiber. Compared to a fiber prepared from polyamide alone, the present fiber exhibits improved heat resistance and flame resistance.
    Type: Grant
    Filed: September 28, 2011
    Date of Patent: July 28, 2015
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Sai-Pei Ting, Olivier Guise, Jung Ah Lee, Richard H. Peters, Hua Guo
  • POLYAMIDE/POLYPHENYLENE ETHER FIBERS AND FIBER-FORMING METHOD
    Publication number: 20130078465
    Abstract: A fiber is prepared by melt extruding a composition including specific amounts of a polyamide and a polyphenylene ether along with a compatabilizer. Particular combinations produce fibers having a desirable combination of good tenacity and low denier per fiber. Compared to a fiber prepared from polyamide alone, the present fiber exhibits improved heat resistance and flame resistance.
    Type: Application
    Filed: September 28, 2011
    Publication date: March 28, 2013
    Inventors: Sai-Pei Ting, Olivier Guise, Jung Ah Lee, Richard H. Peters, Hua Guo
  • Method and composition for inhibiting cell proliferation and angiogenesis
    Publication number: 20120252773
    Abstract: A method is provided for treating a patient with a medical condition that involves angiogenesis or HIF-1 overexpression with a compound having the structure of formula (I) wherein Z, x, y, and R1 through R11 are as defined herein.
    Type: Application
    Filed: April 26, 2012
    Publication date: October 4, 2012
    Inventors: Khalid Amin, Joy M. Calaoagan, Wan-Ru Chao, Peter D. Hobbs, Keith R. Laderoute, Richard H. Peters, Masato Tanabe
  • Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
    Patent number: 7772218
    Abstract: Syntheses of steroids such as 3-hydroxy-7?-methyl-21-[2?-methoxy-4?-(diethylaminomethyl)-phenoxy]-19-norpregna-1,3,5(10)triene citrate (“SR 16234”) and analogs thereof are provided, wherein 21-hydroxy-19-norpregna-4-en-3-one serves as a starting material or intermediate. The latter compound may be readily prepared from estrone-3-methyl ether. Certain intermediates in these syntheses also have value as therapeutic agents, for example in the treatment of prostate disorders such as prostatic cancer.
    Type: Grant
    Filed: August 9, 2004
    Date of Patent: August 10, 2010
    Assignee: SRI International
    Inventors: Richard H. Peters, Jyanwei Liu, John G. Johansson, Kenneth J. Ryan, Wan-Ru Chao, Masato Tanabe
  • Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
    Patent number: 6784170
    Abstract: Syntheses of steroids such as 3-hydroxy-7&agr;-methyl-21-[2′-methoxy-4′-(diethylaminomethyl)-phenoxy]-19-norpregna-1,3,5(10)triene citrate (“SR 16234”) and analogs thereof are provided, wherein 21-hydroxy-19-norpregna-4-en-3-one serves as a starting material or intermediate. The latter compound may be readily prepared from estrone-3-methyl ether. Certain intermediates in these syntheses also have value as therapeutic agents, for example in the treatment of prostate disorders such as prostatic cancer.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: August 31, 2004
    Assignee: SRI International
    Inventors: Richard H. Peters, Jyanwei Liu, John G. Johansson, Kenneth J. Ryan, Wan-Ru Chao, Masato Tanabe
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Patent number: 6747018
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: June 8, 2004
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Publication number: 20030153543
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Application
    Filed: December 19, 2002
    Publication date: August 14, 2003
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Patent number: 6548491
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5(10)-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5(10)-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: April 15, 2003
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Patent number: 6503896
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: January 7, 2003
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Patent number: 6455517
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: September 24, 2002
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Publication number: 20020032180
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Application
    Filed: May 31, 2001
    Publication date: March 14, 2002
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Publication number: 20020032181
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Application
    Filed: July 30, 2001
    Publication date: March 14, 2002
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
    Publication number: 20010039269
    Abstract: Syntheses of steroids such as 3-hydroxy-7&agr;-methyl-21-[2′-methoxy-4′-(diethylaminomethyl)-phenoxy]-19-norpregna-1,3,5(10)triene citrate (“SR 16234”) and analogs thereof are provided, wherein 21-hydroxy-19-norpregna-4-en-3-one serves as a starting material or intermediate. The latter compound may be readily prepared from estrone-3-methyl ether. Certain intermediates in these syntheses also have value as therapeutic agents, for example in the treatment of prostate disorders such as prostatic cancer.
    Type: Application
    Filed: February 9, 2001
    Publication date: November 8, 2001
    Inventors: Richard H. Peters, Jyanwei Liu, John G. Johansson, Kenneth J. Ryan, Wan-Ru Chao, Masato Tanabe
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Patent number: 6281205
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5(10)-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5(10)-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: August 28, 2001
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
    Patent number: 6054446
    Abstract: Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: April 25, 2000
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Ling Jong
  • Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use
    Patent number: 6046186
    Abstract: Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) wherein r1 is an optional double bond, R.sup.1 and R.sup.2 are selected from the group consisting of hydrogen and lower alky, or together form a cyclic substituent (II) ##STR1## wherein Q is NH, O or CH.sub.2, and the other various substituents are as defined herein. Pharmaceutical compositions and methods for using the compounds of formula (I) to treat estrogen-dependent disorders are provided as well.
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: April 4, 2000
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Kazuhiko Shigeno
  • Steroid inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
    Patent number: 5861388
    Abstract: Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) ##STR1## wherein X and Y, or Y and Z, form an oxathiazine dioxide ring or a dihydro-oxathiazine dioxide ring, and the other various substituents are as defined herein. Pharmaceutical compositions and methods for using the compounds of formula (I) to treat estrogen-dependent disorders are provided as well.
    Type: Grant
    Filed: December 31, 1997
    Date of Patent: January 19, 1999
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Kazuhiko Shigeno
  • Steriod inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
    Patent number: 5763432
    Abstract: Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) ##STR1## wherein X and Y, or Y and Z, form an oxathiazine dioxide ring or a dihydro-oxathiazine dioxide ring, and the other various substituents are as defined herein. Pharmaceutical compositions and methods for using the compounds of formula (I) to treat estrogen-dependent disorders are provided as well.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: June 9, 1998
    Assignee: SRI International
    Inventors: Masato Tanabe, Richard H. Peters, Wan-Ru Chao, Kazuhiko Shigeno
  • 15,16-seco-19-nor progestins
    Patent number: 5478862
    Abstract: The invention is drawn to 17-oxo-15,16-seco-19-nor steroids which are useful as intermediates in the production of various 15,16-seco-19-nor progestins. These progestins display elevated progestational activity with a minimum of ancillary hormonal activity and are thus useful in the suppression of ovulation in the human female.
    Type: Grant
    Filed: May 13, 1994
    Date of Patent: December 26, 1995
    Assignee: SRI International
    Inventors: Richard H. Peters, Masato Tanabe