Patents by Inventor Richard Harland

Richard Harland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10261092
    Abstract: Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising cross-reactive antigenic determinants, in particular for determining proteins that are cross-reactive based on serological screens using sequential immunological challenges to an animal, including determining cross-reactive H. parasuis proteins. Also provided are compositions, vaccines, and kits using the molecules for diagnostics and methods for preventing or treating a disease, disorder, condition, or symptoms thereof associated with infectious agents, in particular infectious microorganisms, in particular for preventing or treating a disease, disorder, condition, or symptom thereof associated with H. parasuis infection.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: April 16, 2019
    Assignee: Elanco Tiergesundheit AG
    Inventors: Thomas Plocher, Manuel Campos, Richard Harland, Todd Johnson, Trent Harbison, Dan Keil
  • Publication number: 20150293118
    Abstract: Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising cross-reactive antigenic determinants, in particular for determining proteins that are cross-reactive based on serological screens using sequential immunological challenges to an animal, including determining cross-reactive H. parasuis proteins. Also provided are compositions, vaccines, and kits using the molecules for diagnostics and methods for preventing or treating a disease, disorder, condition, or symptoms thereof associated with infectious agents, in particular infectious microorganisms, in particular for preventing or treating a disease, disorder, condition, or symptom thereof associated with H. parasuis infection.
    Type: Application
    Filed: April 27, 2015
    Publication date: October 15, 2015
    Applicant: NOVARTIS TIERGESUNDHEIT AG
    Inventors: Thomas Plocher, Manuel Campos, Richard Harland, Todd Johnson, Trent Harbison, Dan Keil
  • Patent number: 9046528
    Abstract: Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising cross-reactive antigenic determinants, in particular for determining proteins that are cross-reactive based on serological screens using sequential immunological challenges to an animal, including determining cross-reactive H. parasuis proteins. Also provided are compositions, vaccines, and kits using the molecules for diagnostics and methods for preventing or treating a disease, disorder, condition, or symptoms thereof associated with infectious agents, in particular infectious microorganisms, in particular for preventing or treating a disease, disorder, condition, or symptom thereof associated with H. parasuis infection.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: June 2, 2015
    Assignee: Novartis Tiergesundheit AG
    Inventors: Thomas Plocher, Manuel Campos, Richard Harland, Todd Johnson, Trent Harbison, Dan Keil
  • Patent number: 8637046
    Abstract: The disclosure relates generally to the treatment or prevention of disease in cattle. More particularly, the invention is directed to the production and use of modified bovine herpesvirus 1 (BHV-1) and their use in compositions and vaccines that protect cattle from BHV-1 infection while not suppressing the immunological response in the host. In one example, the invention is directed to the use of modified BHV-1, administered with additional immunogens, either through co-administration and/or through administration in combination vaccines, and the use of these vaccines for the protection of cattle from disease. In one example, use of the modified BHV-1 in the administered compositions facilitates an immune response to or against the additional immunogens.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: January 28, 2014
    Assignees: Cornell University, Novartis AG
    Inventors: Nikolaus Osterrieder, Benedikt B. Kaufer, Gopinath Raju Seetharaman, Richard Harland, Lee David Albee, II, Mayur Navnitbhai Patel
  • Publication number: 20120318521
    Abstract: A method for controlling hydrocarbons flowing from a subsea structure comprises lowering an adapter from the surface to a subsea structure. The adapter has a through bore extending between an upper connector having a first connector profile and a lower connector having a second connector profile that is different than the first connector profile. In addition, the method comprises coupling the lower connector of the adapter to the subsea structure. Further, the method comprises lowering a containment cap from the surface to the adapter. Still further, the method comprises coupling the containment cap to the upper connector of the adapter.
    Type: Application
    Filed: May 10, 2012
    Publication date: December 20, 2012
    Applicant: BP CORPORATION NORTH AMERICA INC.
    Inventors: Robert Winfield Franklin, Richard Harland, Stuart Douglas Rettie, Roy Bryant Shilling, III
  • Publication number: 20120318522
    Abstract: A modular containment cap for containing a subsea wellbore discharging hydrocarbons comprises a lower assembly including a spool body having an upper end, a lower end opposite the upper end, and a first throughbore extending from the upper end to the lower end. In addition the containment cap comprises an upper assembly including a spool piece having an upper end, a lower end opposite the upper end, a throughbore extending from the upper end to the lower end, and a first spool piece valve disposed in the throughbore. The first spool piece valve is configured to control the flow of fluids through the throughbore of the spool piece. The upper end of the spool body is releasably connected to the lower end of the spool piece, and the first throughbore of the spool body is coaxially aligned with and in fluid communication with the throughbore of the spool piece.
    Type: Application
    Filed: May 10, 2012
    Publication date: December 20, 2012
    Applicant: BP Corporation North America Inc.
    Inventors: Robert Winfield Franklin, Richard Harland, Stuart Douglas Rettie, Roy Bryant Shilling, III
  • Publication number: 20120034262
    Abstract: The disclosure relates generally to the treatment or prevention of disease in cattle. More particularly, the invention is directed to the production and use of modified bovine herpesvirus 1 (BHV-1) and their use in compositions and vaccines that protect cattle from BHV-1 infection while not suppressing the immunological response in the host. In one example, the invention is directed to the use of modified BHV-1, administered with additional immunogens, either through co-administration and/or through administration in combination vaccines, and the use of these vaccines for the protection of cattle from disease. In one example, use of the modified BHV-1 in the administered compositions facilitates an immune response to or against the additional immunogens.
    Type: Application
    Filed: October 1, 2009
    Publication date: February 9, 2012
    Applicants: NOVARTIS AG, CORNELL UNIVERSITY
    Inventors: Nikolaus Osterrieder, Benedikt B. Kaufer, Gopinath Raju Seetharaman, Richard Harland, Lee David Albee, II, Mayur Navnitbhai Patel
  • Publication number: 20110014225
    Abstract: Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising cross-reactive antigenic determinants, in particular for determining proteins that are cross-reactive based on serological screens using sequential immunological challenges to an animal, including determining cross-reactive H. parasuis proteins. Also provided are compositions, vaccines, and kits using the molecules for diagnostics and methods for preventing or treating a disease, disorder, condition, or symptoms thereof associated with infectious agents, in particular infectious microorganisms, in particular for preventing or treating a disease, disorder, condition, or symptom thereof associated with H. parasuis infection.
    Type: Application
    Filed: March 20, 2009
    Publication date: January 20, 2011
    Applicant: NOVARTIS AG
    Inventors: Thomas Plocher, Manuel Campos, Richard Harland, Todd Johnson, Trent Harbison, Dan Kiel
  • Patent number: 6571667
    Abstract: A latch device for a manual tong apparatus that incorporates a secondary catch mechanism is presented. Such a secondary catch would assist in maintaining the tong assembly in it's closed position during a reversing operation or at a time when load applied to the manual tong device in the gripping direction is very low. Additionally the secondary catch would also provide some additional protection by holding the tong assembly together in the event of a failure of certain tong components. The mechanism of the secondary catch is spring loaded and operates through two secondary up-down catch arms that are deactivated by swinging a handle in the direction that corresponds to the operator's natural motion to open the lug jaw.
    Type: Grant
    Filed: December 6, 2000
    Date of Patent: June 3, 2003
    Assignee: National-Oilwell, L.P.
    Inventors: Herman Paul Price, Richard Harland Miller, William Harold Macon
  • Publication number: 20030091579
    Abstract: Methods for raising uncastrated male animals for meat production are disclosed. The methods use compositions which include GnRH immunogens. The methods are useful for producing cuts of meat with enhanced organoleptic qualities.
    Type: Application
    Filed: May 5, 1999
    Publication date: May 15, 2003
    Inventors: JACK G. MANNS, STEPHEN D. ACRES, RICHARD HARLAND
  • Publication number: 20020192219
    Abstract: DAN (Differential-screening-selected gene Aberrative in Neuroblastoma) and gremlin proteins and related nucleic acids are provided. Included are natural DAN and gremlin homologs from several species and proteins comprising a DAN or gremlin domain having specific activity, particularly the ability to antagonize a bone morphogenic protein. The proteins may be produced recombinantly from transformed host cells with the subject nucleic acids. Also provided are isolated hybridization probes and primers capable of specifically hybridizing with the disclosed genes, specific binding agents and methods of making and using the subject compositions.
    Type: Application
    Filed: May 29, 2002
    Publication date: December 19, 2002
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Richard Harland, David Hsu
  • Patent number: 6432410
    Abstract: DAN (Differential-screening-selected gene Aberrative in Neuroblastoma) and gremlin proteins and related nucleic acids are provided. Included are natural DAN and gremlin homologs from several species and proteins comprising a DAN or gremlin domain having specific activity, particularly the ability to antagonize a bone morphogenic protein. The proteins may be produced recombinantly from transformed host cells with the subject nucleic acids. Also provided are isolated hybridization probes and primers capable of specifically hybridizing with the disclosed genes, specific binding agents and methods of making and using the subject compositions.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: August 13, 2002
    Assignee: The Regents of the University of California
    Inventors: Richard Harland, David Hsu
  • Publication number: 20020066339
    Abstract: A latch device for a manual tong apparatus that incorporates a secondary catch mechanism is presented. Such a secondary catch would assist in maintaining the tong assembly in it's closed position during a reversing operation or at a time when load applied to the manual tong device in the gripping direction is very low. Additionally the secondary catch would also provide some additional protection by holding the tong assembly together in the event of a failure of certain tong components. The mechanism of the secondary catch is spring loaded and operates through two secondary up-down catch arms that are deactivated by swinging a handle in the direction that corresponds to the operator's natural motion to open the lug jaw.
    Type: Application
    Filed: December 6, 2000
    Publication date: June 6, 2002
    Inventors: Herman Paul Price, Richard Harland Miller, William Harold Macon
  • Publication number: 20010014330
    Abstract: A method is described for immunoneutralization of endogenous molecules in mammalian subjects, wherein an immunogen is administered via injection to the ear. The method is used to elicit an efficient and uniform immune response sufficient to block or suppress the activity of an endogenous hormone in a vaccinated subject, or to target a diseased cell for an immune response.
    Type: Application
    Filed: February 5, 1998
    Publication date: August 16, 2001
    Inventors: RICHARD HARLAND, JOHN G. MANNS, STEPHEN D. ACRES