Abstract: An automatic medication dispenser is disclosed herein. The automated prescription medication dispensing machine includes a container for housing multiple medication pills. The container has a programmable dispensing system, an audible reminder alert, a biometric sensor and a proximity alarm. Additionally, the dispenser can be programmed to dispense a prescribed dosage at a prescribed time or interval and can only be activated using a biometric fingerprint scanner. Furthermore, the system has an audible reminder alarm for a patient. If the machine is moved from a set location an audible alert is activated to prevent the dispenser from being stolen.

Abstract: The invention relates to O3/P2 mixed-phase sodium-containing doped layered oxide materials which comprise a mixture of a first phase with an O3-type structure and a second phase with a P2-type structure; wherein the O3:P2 mixed-phase sodium-containing doped layered oxide material has the general formula: NaaAbM1c M2 M3eM4f M5 O2±?. The invention also provides a process for making such O3/P2 mixed-phase sodium-containing doped layered oxide materials, and use applications therefor.

Abstract: The invention relates to doped nickelate-containing compounds comprising AaM1VM2WM3XM4yM5ZO2-c wherein A comprises either sodium or a mixed alkali metal in which sodium is the major constituent; M1 is nickel in oxidation state greater than 0 to less than or equal to 4+, M2 comprises a metal in oxidation state greater than 0 to less than or equal to 4+, M3 comprises a metal in oxidation state 2+, M4 comprises a metal in oxidation state greater than 0 to less than or equal to 4+, and M5 comprises a metal in oxidation state 3+ wherein 0?a<1, v>0, at least one of w and y is >0 x?0, z?0 wherein c is determined by a range selected from 0<c?0.1 and wherein (a, v, w, x, y, z and c) are chosen to maintain electroneutrality.

Abstract: The invention relates to electrodes that contain active materials of the formula: AaMbXxOy wherein A is one or more alkali metals selected from lithium, sodium and potassium; M is selected from one or more transition metals and/or one or more non-transition metals and/or one or more metalloids; X comprises one or more atoms selected from niobium, antimony, tellurium, tantalum, bismuth and selenium; and further wherein 0<a?6; b is in the range: 0<b?4; x is in the range 0<x?1 and y is in the range 2?y?10. Such electrodes are useful in, for example, sodium and/or lithium ion battery applications.

Abstract: The invention relates to electrodes comprising doped nickelate-containing compositions comprising a first component-type comprising one or more components with an O3 structure of the general formula: AaM1vM2wM3xM4yM5zO2 wherein A comprises one or more alkali metal selected from sodium, lithium and potassium M1 is nickel in oxidation state 2+, M2 comprises one or more metals in oxidation state 4+, M3 comprises one or more metals in oxidation state 2+, M4 comprises one or more metals in oxidation state 4+, and M5 comprises one or more metals in oxidation state 3+ wherein 0.85?a?1; 0<v<0.

Abstract: The invention relates to doped nickelate-containing material with the general formula: Aa M1v M2w M3x M4y M5z O2-? wherein A comprises one or more alkali metals selected from sodium, lithium and potassium; M1 is nickel in oxidation state 2+, M2 comprises one or more metals in oxidation state 4+, M3 comprises one or more metals in oxidation state 2+, M4 comprises one or more metals in oxidation state 4+, and M5 comprises one or more metals in oxidation state 3+ wherein 0.4?a<0.9, 0<v<0.5, at least one of w and y is >0, x>0, z?0, 0???0.1, and wherein a, v, w, x, y and z are chosen to maintain electroneutrality.

Abstract: The invention relates to electrodes comprising doped nickelate-containing compositions comprising a first component-type comprising one or more components with an 03 structure of the general formula: AaM1vM2wM3xM4yM5zO2 wherein A comprises one or more alkali metal selected from sodium, lithium and potassium M1 is nickel in oxidation state 2+, M2 comprises one or more metals in oxidation state 4+, M3 comprises one or more metals in oxidation state 2+, M4 comprises one or more metals in oxidation state 4+, and M5 comprises one or more metals in oxidation state 3+ wherein 0.855?a?1; 0<v<0.

Abstract: The invention relates to electrodes comprising doped nickelate-containing compositions comprising a first component-type comprising one or more components with an 03 structure of the general formula: AaM1V M2W M3X M4y M5Z O2 wherein A comprises one or more alkali metal selected from sodium, lithium and potassium; M1 is nickel in oxidation state 2+, M2 comprises one or more metals in oxidation state 4+, M3 comprises one or more metals in oxidation state 2+, M4 comprises one or more metals in oxidation state 4+, and M5 comprises one or more metals in oxidation state 3+ wherein 0.85?a?1; 0<v<0.

Abstract: The invention relates to electrodes that contain active materials of the formula: AaMbXxOy wherein A is one or more alkali metals selected from lithium, sodium and potassium; M is selected from one or more transition metals and/or one or more non-transition metals and/or one or more metalloids; X comprises one or more atoms selected from niobium, antimony, tellurium, tantalum, bismuth and selenium; and further wherein 0<a?6; b is in the range: 0<b?4; x is in the range 0<x?1 and y is in the range 2?y?10. Such electrodes are useful in, for example, sodium and/or lithium ion battery applications.

Abstract: The invention relates to a novel solid state process for the preparation of metal-containing compounds comprising the steps i) forming a reaction mixture comprising one or more metal-containing precursor compounds and optionally one or more non-metal-containing reactants, and ii) using one or more hypophosphite-containing materials as a reducing agent; wherein one or more of the hypophosphite-containing materials is used as an agent to reduce one or more of the metal-containing precursor compounds; and further wherein the process is performed in the absence of an oxidizing atmosphere. Materials made by such a process are useful, for example, as electrode materials in alkali metal-ion battery applications.

Abstract: The invention relates to electrodes that contain active materials of the formula: AaMbXxOy wherein A is one or more alkali metals selected from lithium, sodium and potassium; M is selected from one or more transition metals and/or one or more non-transition metals and/or one or more metalloids; X comprises one or more atoms selected from niobium, antimony, tellurium, tantalum, bismuth and selenium; and further wherein 0<a?6; b is in the range: 0<b?4; x is in the range 0<x?1 and y is in the range 2?y?10. Such electrodes are useful in, for example, sodium and/or lithium ion battery applications.

Abstract: The invention relates to a novel process for the preparation of metal-containing compounds comprising the steps of a) forming a mixture comprising i) elemental phosphorus and ii) one or more metal-containing precursor compounds, and b) heating the mixture to a temperature of at least 150° C. Materials made by such a process are useful, for example, as electrode materials in alkali metal-ion battery applications.

Abstract: The invention relates to novel electrodes containing one or more active materials comprising: AaM1vM2wM3xM4YM5zO2?C(Formula 1) wherein A comprises either sodium or a mixed alkali metal in which sodium is the constituent; M1 is nickel in oxidation state less than or equal to 4+, M2 comprises a metal in oxidation state less than or equal to 4+, M3 comprises a metal in oxidation state 2+, M4 comprises a metal in oxidation state less than or equal to 4+, and M5 comprises a metal in oxidation state 3+ wherein 0?a?1 v>0 at least one of w and y is >0 x?0 z?0 c>0.1 where (a, v, w, x, y, z and c) are chosen to maintain electroneutrality. Such materials are useful, for example, as electrode materials in sodium-ion battery applications.

Abstract: The invention relates to novel materials of the formula: A1-?M1VM2WM3XM4YM5ZO2 wherein A is one or more alkali metals comprising sodium and/or potassium either alone or in a mixture with lithium as a minor constituent; M1 is nickel in oxidation state +2; M2 comprises a metal in oxidation state +4 selected from one or more of manganese, titanium and zirconium; M3 comprises a metal in oxidation state +2, selected from one or more of magnesium, calcium, copper, zinc and cobalt; M4 comprises a metal in oxidation state +4, selected from one or more of titanium, manganese and zirconium; M5 comprises a metal in oxidation state +3, selected from one or more of aluminum, iron, cobalt, molybdenum, chromium, vanadium, scandium and yttrium; wherein 0???0.1 V is in the range 0<V<0.5; W is in the range 0<W?0.5; X is in the range 0?X<0.5; Y is in the range 0?Y<0.5; Z is ?0; and further wherein V+W+X+Y+Z=1. Such materials are useful, for example, as electrode materials in sodium ion battery applications.

Abstract: The invention relates to novel materials of the formula: AuM1vM2wM3XM4yM5ZO2 wherein A comprises one or more alkali metals selected from lithium, sodium and potassium; M1 is nickel in oxidation state +2 M2 comprises a metal in oxidation state +4 selected from one or more of manganese, titanium and zirconium; M3 comprises a metal in oxidation state +2, selected from one or more of magnesium, calcium, copper, zinc and cobalt; M4 comprises a metal in oxidation state +4, selected from one or more of titanium, manganese and zirconium; M5 comprises a metal in oxidation state +3, selected from one or more of aluminum, iron, cobalt, molybdenum, chromium, vanadium, scandium and yttrium; further wherein U is in the range 1<U<2; V is in the range 0.25<V<1; W is in the range 0<W<0.75; X is in the range 0?X<0.5; Y is in the range 0?Y<0.5; Z is in the range 0?Z<0.5; and further wherein (U+V+W+X+Y+Z)?3.

Abstract: The invention relates to electrodes comprising doped nickelate-containing compositions comprising a first component-type comprising one or more components with an 03 structure of the general formula: AaM1VM2WM3XM4yM5ZO2 wherein A comprises one or more alkali metal selected from sodium, lithium and potassium; M1 is nickel in oxidation state 2+, M2 comprises one or more metals in oxidation state 4+, M3 comprises one or more metals in oxidation state 2+, M4 comprises one or more metals in oxidation state 4+, and M5 comprises one or more metals in oxidation state 3+ wherein 0.85?a?1; 0<v<0.

Abstract: The invention relates to doped nickelate-containing material with the general formula: AaMv1Mw2Mx3My4Mz5O2-? wherein A comprises one or more alkali metals selected from sodium, lithium and potassium; M1 is nickel in oxidation state 2+, M2 comprises one or more metals in oxidation state 4+, M3 comprises one or more metals in oxidation state 2+, M4 comprises one or more metals in oxidation state 4+, and M5 comprises one or more metals in oxidation state 3+ wherein 0.4?a<0.9, 0<v<0.5, at least one of w and y is >0, x>0, z?0, 0???0.1, and wherein a, v, w, x, y and z are chosen to maintain electroneutrality.

Abstract: The invention relates to doped nickelate-containing compounds comprising AaM1VM2WM3XM4yM5ZO2-c wherein A comprises either sodium or a mixed alkali metal in which sodium is the major constituent; M1 is nickel in oxidation state greater than 0 to less than or equal to 4+, M2 comprises a metal in oxidation state greater than 0 to less than or equal to 4+, M3 comprises a metal in oxidation state 2+, M4 comprises a metal in oxidation state greater than 0 to less than or equal to 4+, and M5 comprises a metal in oxidation state 3+ wherein 0?a<1, v>0, at least one of w and y is >0 x?0, z?0 wherein c is determined by a range selected from 0<c?0.1 and wherein (a, v, w, x, y, z and c) are chosen to maintain electroneutrality.

Abstract: The invention relates to a novel solid state process for the preparation of metal-containing compounds comprising the steps i) forming a reaction mixture comprising one or more metal-containing precursor compounds and optionally one or more non-metal-containing reactants, and ii) using one or more hypophosphite-containing materials as a reducing agent; wherein one or more of the hypophosphite-containing materials is used as an agent to reduce one or more of the metal-containing precursor compounds; and further wherein the process is performed in the absence of an oxidizing atmosphere. Materials made by such a process are useful, for example, as electrode materials in alkali metal-ion battery applications.

Abstract: The present invention provides a method for predicting the risk of a patient for developing adverse drug reactions, particularly thiopurine induced pancreatitis (TIP). The invention also provides a method of identifying a subject afflicted with, or at risk of, developing TIP. In some aspects, the methods comprise analyzing at least one genetic marker, wherein the presence of the at least one genetic marker indicates that the subject is afflicted with, or at risk of, developing TIP.