Patents by Inventor Richard Hung Chiu Yu

Richard Hung Chiu Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS
    Publication number: 20190359644
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Application
    Filed: December 20, 2018
    Publication date: November 28, 2019
    Inventors: Richard Hung Chiu Yu, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • Processes and intermediates for preparing anti-HIV agents
    Patent number: 10196419
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: February 5, 2019
    Assignee: Gilead Sciences, Inc.
    Inventors: Richard Hung Chiu Yu, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS
    Publication number: 20180079773
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Application
    Filed: September 6, 2017
    Publication date: March 22, 2018
    Inventors: Richard Hung Chiu Yu, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • Processes and intermediates for preparing anti-HIV agents
    Patent number: 9783567
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: October 10, 2017
    Assignee: Gilead Sciences, Inc.
    Inventors: Richard Hung Chiu Yu, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • CRYSTALLINE FORM
    Publication number: 20170217952
    Abstract: The invention provides a crystalline form of the compound of formula (Ia), methods for making the crystalline form of the compound of formula (Ia), and therapeutic methods for the use of the crystalline form of the compound of formula (Ia).
    Type: Application
    Filed: January 24, 2017
    Publication date: August 3, 2017
    Inventors: Chiajen Lai, Lok Him Lawrence Yu, Richard Hung Chiu Yu
  • Methods of preparing toll-like receptor modulators
    Patent number: 9573952
    Abstract: The present invention provides methods of preparing 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one and related compounds.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: February 21, 2017
    Assignee: Gilead Sciences, Inc.
    Inventors: Darin Allen, Brandon Heath Brown, Jessica Jade Chao, Randall L. Halcomb, Paul Hrvatin, Ryan McFadden, Paul Roethle, Erwina Rudio, Hong Yang, Richard Hung Chiu Yu
  • PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS
    Publication number: 20160340379
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Application
    Filed: February 17, 2016
    Publication date: November 24, 2016
    Inventors: RICHARD HUNG CHIU YU, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • Methods and intermediates for preparing pharmaceutical agents
    Patent number: 9346796
    Abstract: Methods and intermediates useful for preparing a compound of formula I: and salts thereof.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: May 24, 2016
    Assignee: Gilead Sciences, Inc.
    Inventors: Aaron J. Cullen, Richard Hung Chiu Yu
  • Tenofovir alafenamide hemifumarate
    Patent number: 9296769
    Abstract: A hemifumarate form of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine (tenofovir alafenamide), and antiviral therapy using tenofovir alafenamide hemifumarate (e.g., anti-HIV and anti-HBV therapies).
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: March 29, 2016
    Assignee: Gilead Sciences, Inc.
    Inventors: Dazhan Liu, Bing Shi, Fang Wang, Richard Hung Chiu Yu
  • Processes and intermediates for preparing anti-HIV agents
    Patent number: 9296779
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: March 29, 2016
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Richard Hung Chiu Yu, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Duc-Phi Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • METHODS OF PREPARING TOLL-LIKE RECEPTOR MODULATORS
    Publication number: 20160075707
    Abstract: The present invention provides methods of preparing 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one and related compounds.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 17, 2016
    Inventors: Darin Allen, Brandon Heath Brown, Jessica Jade Chao, Randall L. Halcomb, Paul Hrvatin, Ryan McFadden, Paul Roethle, Erwina Rudio, Hong Yang, Richard Hung Chiu Yu
  • PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS
    Publication number: 20150203525
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Application
    Filed: February 5, 2015
    Publication date: July 23, 2015
    Inventors: Richard Hung Chiu YU, Brandon Heath BROWN, Richard P. POLNIASZEK, Benjamin R. GRAETZ, Keiko SUJINO, Duong Duc-Phi TRAN, Alan Scott TRIMAN, Kenneth M. KENT, Steven PFEIFFER
  • Processes and intermediates for preparing anti-HIV Agents
    Patent number: 8987437
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: March 24, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Richard Hung Chiu Yu, Brandon Heath Brown, Richard P. Polniaszek, Benjamin R. Graetz, Keiko Sujino, Duong Duc-Phi Tran, Alan Scott Triman, Kenneth M. Kent, Steven Pfeiffer
  • PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR PREPARATION
    Publication number: 20150004239
    Abstract: The invention provides solid particles comprising: a) a solid core that comprises an active pharmaceutical agent and b) a coating of Compound 2: (2) or a pharmaceutically acceptable salt of thereof on the core, as well as compositions comprising such particles, and methods for treating diseases (e.g. HIV infection) with such particles.
    Type: Application
    Filed: January 11, 2013
    Publication date: January 1, 2015
    Inventors: Aaron J. Cullen, Richard Hung Chiu Yu
  • METHODS AND INTERMEDIATES FOR PREPARING PHARMACEUTICAL AGENTS
    Publication number: 20140364602
    Abstract: Methods and intermediates useful for preparing a compound of formula I: and salts thereof.
    Type: Application
    Filed: February 1, 2013
    Publication date: December 11, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Aaron J. Cullen, Richard Hung Chiu Yu
  • TENOFOVIR ALAFENAMIDE HEMIFUMARATE
    Publication number: 20140187773
    Abstract: A hemifumarate form of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine (tenofovir alafenamide), and antiviral therapy using tenofovir alafenamide hemifumarate (e.g., anti-HIV and anti-HBV therapies).
    Type: Application
    Filed: March 5, 2014
    Publication date: July 3, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Dazhan Liu, Bing Shi, Fang Wang, Richard Hung Chiu Yu
  • Tenofovir alafenamide hemifumarate
    Patent number: 8754065
    Abstract: A hemifumarate form of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine (tenofovir alafenamide), and antiviral therapy using tenofovir alafenamide hemifumarate (e.g., anti-HIV and anti-HBV therapies).
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: June 17, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Dazhan Liu, Bing Shi, Fang Wang, Richard Hung Chiu Yu
  • Tenofovir alafenamide hemifumarate
    Patent number: 8697675
    Abstract: A hemifumarate form of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine (tenofovir alafenamide), and antiviral therapy using tenofovir alafenamide hemifumarate (e.g., anti-HIV and anti-HBV therapies).
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: April 15, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Dazhan Liu, Bing Shi, Fang Wang, Richard Hung Chiu Yu
  • Process for preparation of HIV protease inhibitors
    Patent number: 8431745
    Abstract: A process for the synthesis of bisfuran intermediates useful for preparing antiviral HIV protease inhibitor compounds is hereby disclosed.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: April 30, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Kenneth R. Crawford, Eric D. Dowdy, Arnold Gutierrez, Richard P. Polniaszek, Richard Hung Chiu Yu
  • TENOFOVIR ALAFENAMIDE HEMIFUMARATE
    Publication number: 20130065856
    Abstract: A hemifumarate form of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine (tenofovir alafenamide), and antiviral therapy using tenofovir alafenamide hemifumarate (e.g., anti-HIV and anti-HBV therapies).
    Type: Application
    Filed: August 15, 2012
    Publication date: March 14, 2013
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Dazhan Liu, Bing Shi, Fang Wang, Richard Hung Chiu Yu