Patents by Inventor Richard J. Auchus

Richard J. Auchus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligands for nematode nuclear receptors and uses thereof
    Patent number: 10117878
    Abstract: An effective anti-nematode methodology entails contacting nematodes with a biologically effective amount of at least one compound according to formula I: where Q, Q?, R1, R2, and n are defined herein, or with a stereoisomer, solvate, or pharmaceutically acceptable salt of such compound.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: November 6, 2018
    Assignee: Board of Regents, University of Texas System
    Inventors: David J. Mangelsdorf, Richard J. Auchus, Daniel L. Motola, Carolyn L. Cummins, Kamalesh K. Sharma
  • DETECTION OF MINERALOCORTICOID RECEPTOR ACTIVATION AND PERSONALIZED ANTIHYPERTENSIVE THERAPY BASED THEREON
    Publication number: 20170335399
    Abstract: Provided herein are compositions and methods for the assessment of mineralocorticoid receptor activation or repression, and methods of customizing antihypertensive therapies based thereon. In particular, assays are provided for the detection of targets of mineralocorticoid receptor activation.
    Type: Application
    Filed: June 1, 2017
    Publication date: November 23, 2017
    Inventors: James Brian Byrd, Richard J. Auchus, William Rainey
  • DETECTION OF MINERALOCORTICOID RECEPTOR ACTIVATION AND PERSONALIZED ANTIHYPERTENSIVE THERAPY BASED THEREON
    Publication number: 20160090628
    Abstract: Provided herein are compositions and methods for the assessment of mineralocorticoid receptor activation or repression, and methods of customizing antihypertensive therapies based thereon. In particular, assays are provided for the detection of targets of mineralocorticoid receptor activation.
    Type: Application
    Filed: September 25, 2015
    Publication date: March 31, 2016
    Inventors: James Brian Byrd, Richard J. Auchus, William Rainey
  • LIGANDS FOR NEMATODE NUCLEAR RECEPTORS AND USES THEREOF
    Publication number: 20110028443
    Abstract: An effective anti-nematode methodology entails contacting nematodes with a biologically effective amount of at least one compound according to formula I: where Q, Q?, R1, R2, and n are defined herein, or with a stereoisomer, solvate, or pharmaceutically acceptable salt of such compound.
    Type: Application
    Filed: October 15, 2010
    Publication date: February 3, 2011
    Inventors: David J. MANGELSDORF, Richard J. AUCHUS, Daniel L. MOTOLA, Carolyn L. CUMMINS, Kamalesh K. SHARMA
  • Ligands for nematode nuclear receptors and uses thereof
    Patent number: 7825269
    Abstract: Anti-nematode compounds, compositions, and methods for identifying such compounds are disclosed, where the compounds have the formula I: where Q, Q?, R1, R2, and n are defined herein.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: November 2, 2010
    Assignee: Board of Regents, University of Texas System
    Inventors: David J. Mangelsdorf, Richard J. Auchus, Daniel L. Motola, Carolyn L. Cummins, Kamalesh K. Sharma