Patents by Inventor Richard J. Babaian

Richard J. Babaian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Unique protein marker for bladder cancer
    Patent number: 5359031
    Abstract: The present invention involves a method for detecting bladder cancer in a subject. The method preferably comprises first collecting a urine sample from the subject. The presence of a proteinaceous substance having a molecular weight of about 180 kDa according to its relative electrophoretic migration rate through detergent-containing polyacrylamide gel is then measured. This substance reversibly binds concanavalin A and is complexed with gamma globulin while in the urine. The gamma globulin complex binds to Staphlococcal protein A. Said proteinaceous substance, when present in detectable amount, is an indicator of bladder cancer.
    Type: Grant
    Filed: April 28, 1992
    Date of Patent: October 25, 1994
    Assignee: Board of Regents, The University of Texas System
    Inventors: Haiyen E. Zhau, Richard J. Babaian
  • Unique protein marker for bladder cancer
    Patent number: 5221612
    Abstract: The present invention involves a method for detecting bladder cancer in a subject. The method preferably comprises first collecting a urine sample from the subject. The presence of a proteinaceous substance having a molecular weight of about 180 kDa according to its relative electrophoretic migration rate through detergent-containing polyacrylamide gel is then measured. This substance reversibly binds concanavalin A and is complexed with gamma globulin while in the urine. The gamma globulin complex binds to Staphlococcal protein A. Said proteinaceous substance, when present in detectable amount, is an indicator of bladder cancer.The method of the present invention for diagnosing bladder cancer in a subject may also be described as comprising detection in a urine sample from said subject of a proteinaceous substance having a molecular weight of about 180 kDa and being unreactive with antibodies specifically binding to carcinoembryonic antigen or epidermal growth factor receptor.
    Type: Grant
    Filed: March 3, 1989
    Date of Patent: June 22, 1993
    Assignee: Board of Regents, The University of Texas System
    Inventors: Haiyen E. Zhau, Richard J. Babaian