Patents by Inventor Richard J. Douthart

Richard J. Douthart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5707506
    Abstract: This invention is a channel plate that facilitates data compaction in DNA sequencing. The channel plate has a length, a width and a thickness, and further has a plurality of channels that are parallel. Each channel has a depth partially through the thickness of the channel plate. Additionally an interface edge permits electrical communication across an interface through a buffer to a deposition membrane surface.
    Type: Grant
    Filed: May 6, 1996
    Date of Patent: January 13, 1998
    Assignee: Battelle Memorial Institute
    Inventors: Richard J. Douthart, Shannon L. Crowell
  • Patent number: 5514256
    Abstract: This invention is a means for the rapid sequencing of DNA samples. More specifically, it consists of a new design direct blotting electrophoresis unit. The DNA sequence is deposited on a membrane attached to a rotating drum. Initial data compaction is facilitated by the use of a machined multi-channeled plate called a ribbon channel plate. Each channel is an isolated mini gel system much like a gel filled capillary. The system as a whole, however, is in a slab gel like format with the advantages of uniformity and easy reusability. The system can be used in different embodiments. The drum system is unique in that after deposition the drum rotates the deposited DNA into a large non-buffer open space where processing and detection can occur. The drum can also be removed in toto to special workstations for downstream processing, multiplexing and detection.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: May 7, 1996
    Assignee: Battelle Memorial Institute
    Inventors: Richard J. Douthart, Shannon L. Crowell
  • Patent number: 4400375
    Abstract: A complex is described which is useful in inducing interferon production, in activating peritoneal macrophages, and in inhibiting the proliferation and migration of tumor cells, which complex comprises natural or synthetic double stranded RNA and tobramycin.
    Type: Grant
    Filed: November 23, 1981
    Date of Patent: August 23, 1983
    Assignee: Eli Lilly and Company
    Inventors: Richard J. Douthart, Walter J. Kleinschmidt, Richard M. Schultz